Results 71 to 80 of about 16,721 (247)
ProceedingsRheumatic heart disease (RHD) is a devastating consequence of group A streptococcus (StrepA) infections, being associated with 15 [...]
Victoria Ozberk +11 more
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Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
Mass Spectrometry Reviews, EarlyView.ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source
Sample preparation methods for N-glycomics
Advances in Sample Preparation, 2022 Aberrant glycosylation has been associated with the human disease since it involves crucial mechanisms such as tumor onset, development, and progression.
H. Mehmet Kayili +3 more
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The FASEB Journal, 2021 Eukaryotic Vertebrate host glycosylation machinery has been subject to immense evolutionary pressure. Besides, being crucial for host sustenance, glyco‐epitopes are also key‐regulators of inter‐species pathogen transmission. Significant evolutionary events such as loss of N‐glycolyl neuraminic acid (Neu5Gc) or alpha Galactose (α‐Gal) epitopes in ...
Abarna V. M. Murugan +13 more
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Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Sialic acid and platelet count regulation: Implications in immune thrombocytopenia
Research and Practice in Thrombosis and Haemostasis, 2022 Platelets are blood components that survive in circulation for 7 to 10 days in humans. Thus, platelet production by bone marrow (BM) megakaryocytes (MKs), and their removal from the blood circulation is precisely orchestrated to maintain an average ...
Melissa M. Lee‐Sundlov +3 more
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Analytical and Bioanalytical Chemistry / Determination of true ratios of different N-glycan structures in electrospray ionization mass spectrometry [PDF]
, 2017 Nicht verf\ufcgbarAn ideal method for the analysis of N-glycans would both identify the isomeric structure and deliver a true picture of the relative, if not absolute, amounts of the various structures in one sample.
Altmann, Friedrich +4 more
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Glycomics and disease markers [PDF]
Current Opinion in Chemical Biology, 2009 Glycomics is the comprehensive study of all glycans expressed in biological systems. The biosynthesis of glycan relies on a number of highly competitive processes involving glycosyl transferases. Glycosylation is therefore highly sensitive to the biochemical environment and has been implicated in many diseases including cancer.
Hyun Joo, An +3 more
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Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Glyco-biomarkers: Potential determinants of cellular physiology and pathology [PDF]
, 2008 Once dismissed as just the icing on the cake, sugar molecules are emerging as vital components in life’s intricate machinery. Our understanding of their function within the context of the proteins and lipids to which they are attached has matured rapidly,
Alavi, A, Axford, JS
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