Results 11 to 20 of about 23,942 (220)

Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues. [PDF]

Chem Rev, 2017
Okano A, Isley NA, Boger DL.
europepmc   +2 more sources

Two Novel Semisynthetic Lipoglycopeptides Active against Staphylococcus aureus Biofilms and Cells in Late Stationary Growth Phase

Pharmaceuticals, 2021
The increase in antibiotic resistance among Gram-positive bacteria underscores the urgent need to develop new antibiotics. New antibiotics should target actively growing susceptible bacteria that are resistant to clinically accepted antibiotics including
Vladimir Vimberg, Leona Zieglerova, Aninda Mazumdar, Zsolt Szűcs, Aniko Borbás, Pál Herczegh, Gabriela Balikova Novotna   +6 more
doaj   +1 more source

Antibacterial Conjugates of Kanamycin A with Vancomycin and Eremomycin: Biological Activity and a New MS-Fragmentation Pattern of Cbz-Protected Amines

Antibiotics, 2023
A significant increase of microbial resistance to glycopeptides (especially vancomycin-resistant enterococci and Staphylococcus aureus) prompted researchers to design new semisynthetic glycopeptide derivatives, such as dual-action antibiotics that ...
Pavel N. Solyev, Elena B. Isakova, Evgenia N. Olsufyeva   +2 more
doaj   +1 more source

Nanoparticle‐Based Formulations of Glycopeptide Antibiotics: A Means for Overcoming Vancomycin Resistance in Bacterial Pathogens?

Advanced NanoBiomed Research, 2023
The occurrence and spreading of multidrug resistance in bacterial pathogens represent one of the greatest challenges of the 21st century. With fewer and fewer new antibiotics in development, novel and unconventional concepts in drug development and ...
Bhanu Kiran Pothineni, Adrian Keller
doaj   +1 more source

Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics. [PDF]

J Biol Chem, 2019
Marschall E, Cryle MJ, Tailhades J.
europepmc   +2 more sources

Glycopeptide antibiotic biosynthesis [PDF]

The Journal of Antibiotics, 2013
Glycopeptides such as vancomycin, teicoplanin and telavancin are essential for treating infections caused by Gram-positive bacteria. Unfortunately, the dwindled pipeline of new antibiotics into the market and the emergence of glycopeptide-resistant enterococci and other resistant bacteria are increasingly making effective antibiotic treatment difficult.
Grace, Yim, Maulik N, Thaker, Kalinka, Koteva, Gerard, Wright   +3 more
openaire   +2 more sources

What Is the Most Effective Empirical Antibiotic Treatment for Early, Delayed, and Late Fracture-Related Infections?

Antibiotics, 2022
Antibiotic treatment strategies for fracture-related infections (FRI) are often extrapolated from periprosthetic joint infections (PJI), although, in contrast to PJI, detailed analysis of pathogens and their antibiotic resistance is missing.
Susanne Baertl, Nike Walter, Ulrike Engelstaedter, Martin Ehrenschwender, Florian Hitzenbichler, Volker Alt, Markus Rupp   +6 more
doaj   +1 more source

Evaluation of errors during susceptibility reporting of glycopeptide antibiotics for enterococcal isolates on sole basis of widely used disk diffusion test

Healthcare in Low-resource Settings, 2022
In resource limited settings, very often susceptibility reports glycopeptide antibiotics are released only on the basis of disk diffusion test. Determination of MIC by either E-strips or microbroth dilution tests can be of paramount importance in ...
Vikas Saini, Nisha Goyal, Narendra Pal Singh, Meenakshi Goswami   +3 more
doaj   +1 more source

Overview of the analytical methods for vancomycin and/or teicoplanin determination in biological matrices [PDF]

Veterinarski Glasnik, 2017
Background. Teicoplanin and vancomycin are glycopeptide antibiotics currently in use for treatment of multidrug-resistant bacterial infections. Scope and Approach.
Stajić Ana, Jančić-Stojanović Biljana   +1 more
doaj   +1 more source

Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]

, 2020
Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen, Bedernjak, Alexandre F., Cummings, Stephen P., Day, Kathryn M., Gray, Mark, Jones, Amanda L., Marrs, Emma C.L., Perry, John D., Varadi, Linda   +8 more
core   +2 more sources