Results 21 to 30 of about 23,942 (220)
Scientific Reports, 2023 Glycopeptide antibiotics are regularly used in ophthalmology to treat infections of Gram-positive bacteria. Aggregative interactions of antibiotics with mucins however can lead to long exposure and increases the risk of resistant species.
Taewoo Chun +6 more
doaj +1 more source
Glycopeptide Antibiotic Resistance Genes in Glycopeptide-Producing Organisms [PDF]
Antimicrobial Agents and Chemotherapy, 1998 ABSTRACT The mechanism of high-level resistance to vancomycin in enterococci consists of the synthesis of peptidoglycan terminating in d -alanyl- d -lactate instead of the usual d -alanyl- d -alanine.
C G, Marshall +3 more
openaire +2 more sources
GPAHex-A synthetic biology platform for Type IV–V glycopeptide antibiotic production and discovery
Nature Communications, 2020 Expansion of the chemical diversity of glycopeptide antibiotics (GPAs) to deal with the emergence and spread of GPA resistance is challenging. Here, the authors report a GPA synthetic biology platform in Streptomyces coelicolor for Type IV–V glycopeptide
Min Xu +5 more
doaj +1 more source
A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics. [PDF]
Medchemcomm, 2017 Sarkar P +3 more
europepmc +2 more sources
Molecules, 2021 Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and food additives are being commercialized as racemic mixtures, although in most cases only one of the isomers possesses the desirable properties. As our understanding
Róbert Berkecz +3 more
doaj +1 more source
Genome sequencing analysis of Streptomyces coelicolor mutants that overcome the phosphate-depending vancomycin lethal effect [PDF]
, 2018 Background Glycopeptide antibiotics inhibit bacterial cell-wall synthesis, and are important for the treatment of infections caused by multi drug-resistant strains of enterococci, streptococci and staphylococci.
Santos Beneit, Fernando
core +1 more source
Frontiers in Microbiology, 2023 Staphylococcus aureus is part of normal human flora and is widely associated with hospital-acquired bacteremia. S. aureus has shown a diverse array of resistance to environmental stresses and antibiotics. Methicillin-resistant S.
Gul Habib +7 more
doaj +1 more source
Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]
, 2015 This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC +6 more
core +1 more source
Pharmaceuticals, 2023 Glycopeptide antibiotics are still in demand in clinical practice for treating infections caused by resistant gram-positive pathogens; however, their use is limited due to severe adverse reactions.
Michael I. Treshchalin +6 more
doaj +1 more source
Antibiotic resistance mechanisms inform discovery: identification and characterization of a novel amycolatopsis strain producing ristocetin. [PDF]
, 2014 Discovering new antibiotics is a major scientific challenge, made increasingly urgent by the continued development of resistance in bacterial pathogens.
Cheng, Jinhua +5 more
core +2 more sources