Results 41 to 50 of about 124,462 (290)

Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]

open access: yes, 2003
Indexación: ScieloWe report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
Fernández, Jorge   +9 more
core   +2 more sources

Antiplatelet Activity of Tussilagone via Inhibition of the GPVI Downstream Signaling Pathway in Platelets

open access: yesFrontiers in Medicine, 2020
Tussilagone is a sesquiterpenoid extracted from Tussilago farfara and is used as an oriental medicine for asthma and bronchitis. Although previous studies have shown that tussilagone has an inhibitory effect on platelet aggregation, no studies have been ...
Jing Zhou   +4 more
doaj   +1 more source

Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core.

open access: yesPLoS Pathogens, 2023
The spike (S) glycoprotein of SARS CoV-2 is the target of neutralizing antibodies (NAbs) that are crucial for vaccine effectiveness. The S1 subunit binds ACE2 while the S2 subunit mediates virus-cell membrane fusion.
Pantelis Poumbourios   +12 more
doaj   +1 more source

Integrated dataset on acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin [PDF]

open access: yes, 2018
Data herein describe the quantitative changes in the plasma proteome in chickens challenged with lipopolysaccharide (LPS), a bacterial endotoxin known to stimulate the host innate immune system obtained by shotgun quantitative proteomic tandem mass tags ...
Bain, Maureen   +7 more
core   +3 more sources

Collagen can selectively trigger a platelet secretory phenotype via glycoprotein VI. [PDF]

open access: yesPLoS ONE, 2014
Platelets are not only central actors of hemostasis and thrombosis but also of other processes including inflammation, angiogenesis, and tissue regeneration.
Véronique Ollivier   +6 more
doaj   +1 more source

Drug absorption through a cell monolayer: a theoretical work on a non-linear three-compartment model [PDF]

open access: yes, 2009
The subject of analysis is a non-linear three-compartment model, widely used in pharmacological absorption studies. It has been transformed into a general form, thus leading automatically to an appropriate approximation.
Acharya   +31 more
core   +2 more sources

Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study [PDF]

open access: yes, 2012
The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional
Bausek N.   +37 more
core   +1 more source

An optimized herbal medicine containing Scutellaria baicalensis Georgi, Alisma orientale Juzepzuk, and Atractylodes japonica Koidzumi has potent antiplatelet and antithrombotic activities

open access: yesJournal of Traditional and Complementary Medicine, 2023
Background and aim: Platelet-derived thrombosis is important in the pathogenesis of cardiovascular diseases. HTB is an optimized herbal medicine including Scutellaria baicalensis Georgi, Alisma orientale Juzepzuk, and Atractylodes japonica Koidzumi.
Yeon-Ji Kim, Tae In Kim, Kyungho Kim
doaj   +1 more source

Biomechanical thrombosis: the dark side of force and dawn of mechano-medicine

open access: yesStroke and Vascular Neurology, 2020
Arterial thrombosis is in part contributed by excessive platelet aggregation, which can lead to blood clotting and subsequent heart attack and stroke. Platelets are sensitive to the haemodynamic environment.
Yunfeng Chen, Lining Arnold Ju
doaj   +1 more source

Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity [PDF]

open access: yes, 1978
INFECTION of mice with viruses can generate cytotoxic T lymphocytes (CTL) which show restricted specificity for target cell lysis. Specific lysis requires that the virus used to prime the target cells must be of the same type as that used to sensitise ...
A Munro   +12 more
core   +1 more source

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