Results 11 to 20 of about 87,090 (247)
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]
International Journal of Molecular Sciences, 2019 Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Shravan Morla
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Glycosaminoglycans and Proteoglycans [PDF]
Pharmaceuticals, 2018 In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan, serglycin, cell-surface proteoglycans, like syndecans and glypicans, and the extracellular matrix ...
Vitor Pomin, Barbara Mulloy
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Axonal Regeneration by Glycosaminoglycan [PDF]
Frontiers in Cell and Developmental Biology, 2021 Like other biomolecules including nucleic acid and protein, glycan plays pivotal roles in various cellular processes. For instance, it modulates protein folding and stability, organizes extracellular matrix and tissue elasticity, and regulates membrane trafficking.
Kazuma Sakamoto +4 more
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Glycosaminoglycans in biomedicine [PDF]
WIREs Nanomedicine and Nanobiotechnology, 2013 AbstractGlycosaminoglycans (GAGs) compose one of four classes of mammalian biopolymers, and are arguably the most complex. The research areas of glycobiology, glycopolymers, and the use of GAGs within tissue engineering and regenerative medicine have grown exponentially during the past decade.
Alyssa Panitch, Rebecca A. Scott
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Glycosaminoglycans and infection [PDF]
Frontiers in Bioscience, 2016 Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular compartments, at the cell surface, and in the extracellular environment where they interact with various molecules to regulate many cellular processes implicated in health and disease. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial
Rafael S. Aquino, Pyong Woo Park
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Glycosaminoglycans and the peritoneaum [PDF]
Nephrology, 2002 SUMMARY: The introduction of peritoneal dialysis (PD) over two decades ago has allowed us to manipulate the peritoneal membrane to perform as a continuous dialysing organ. to maximize the efficacy of solute transport and waste removal, conventional PD fluids require unphysiological concentrations of glucose to provide the osmotic drive, lactate to ...
Yung, S, Chan, TM
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A method for characterising human intervertebral disc glycosaminoglycan disaccharides using liquid chromatography-mass spectrometry with multiple reaction monitoring [PDF]
European Cells & Materials, 2018 Intervertebral disc (IVD) degeneration results in the depletion of proteoglycans and glycosaminoglycans (GAGs), which can lead to structural and mechanical loss of IVD function, ingrowth of nociceptive nerve fibres and eventually discogenic pain ...
X Liu +7 more
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Frontiers in Molecular Biosciences, 2020 Self-propagating form of the prion protein (PrPSc) causes many neurodegenerative diseases, such as Creutzfeldt-Jakob disease (CJD) and Gerstmann-Straussler-Scheinker syndrome (GSS).
So Young Kim +5 more
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Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease β Secretase, BACE1
Marine Drugs, 2021 Only palliative therapeutic options exist for the treatment of Alzheimer’s Disease; no new successful drug candidates have been developed in over 15 years.
Courtney J. Mycroft-West +10 more
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Molecules, 2022 Glycosaminoglycans (GAGs) are a class of periodic anionic linear polysaccharides involved in a number of biologically relevant processes in the extracellular matrix via interactions with various types of molecules including proteins, peptides and small ...
Martyna Maszota-Zieleniak +2 more
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