Results 51 to 60 of about 87,090 (247)

Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix [PDF]

Open Biology, 2016
The range of biological outcomes generated by many signalling proteins in development and homeostasis is increased by their interactions with glycosaminoglycans, particularly heparan sulfate (HS).
Changye Sun, Marco Marcello, Yong Li, David Mason, Raphaël Lévy, David G. Fernig   +5 more
doaj   +1 more source

Marine Non-Glycosaminoglycan Sulfated Glycans as Potential Pharmaceuticals

Pharmaceuticals, 2015
Sulfated fucans (SFs) and sulfated galactans (SGs) are currently the marine non-glycosaminoglycan (GAG) sulfated glycans most studied in glycomics.
V. Pomin
semanticscholar   +1 more source

The dependence of chemokine-glycosaminoglycan interactions on chemokine oligomerization.

Glycobiology, 2015
Both chemokine oligomerization and binding to glycosaminoglycans (GAGs) are required for their function in cell recruitment. Interactions with GAGs facilitate the formation of chemokine gradients, which provide directional cues for migrating cells.
D. Dyer, Catherina L. Salanga, B. Volkman, T. Kawamura, T. Handel   +4 more
semanticscholar   +1 more source

Structural Elucidation of Glycosaminoglycans in the Tissue of Flounder and Isolation of Chondroitin Sulfate C

Marine Drugs
Glycosaminoglycans (GAGs) are valuable bioactive polysaccharides with promising biomedical and pharmaceutical applications. In this study, we analyzed GAGs using HPLC-MS/MS from the bone (B), muscle (M), skin (S), and viscera (V) of Scophthalmus maximus (
Zhe Wang, Weiwen Wang, Hao Gong, Yudi Jiang, Renjie Liu, Guangli Yu, Guoyun Li, Chao Cai   +7 more
doaj   +1 more source

Glycosaminoglycans in horses with osteoarthritis [PDF]

Equine Veterinary Journal, 1991
SummaryHorse articular cartilage glycosaminoglycans (GAGs) were measured in synovial fluids from 48 joints affected with osteoarthritis (OA), 22 normal joints, four joints with osteochondritis, three joints with traumatic arthritis and seven joints infected with bacteria.
W.H. Alwan, G. B. Edwards, D. Bennett, Stuart D. Carter   +3 more
openaire   +3 more sources

Cant1 Affects Cartilage Proteoglycan Properties: Aggrecan and Decorin Characterization in a Mouse Model of Desbuquois Dysplasia Type 1

Biomolecules
Desbuquois dysplasia type 1 (DBQD1) is a recessive chondrodysplasia caused by mutations in the CANT1 gene, encoding for the Golgi Calcium-Activated Nucleotidase 1 (CANT1). The enzyme hydrolyzes UDP, the by-product of glycosyltransferase reactions, but it
Chiara Gramegna Tota, Alessandra Leone, Asifa Khan, Antonella Forlino, Antonio Rossi, Chiara Paganini   +5 more
doaj   +1 more source

Molecular Modeling of Protein‐Glycosaminoglycan Interactions

Arteriosclerosis, 1989
Forty-nine regions In 21 proteins were Identified as potential heparln-blnding sites based on the sequence organizations of their basic and nonbaslc residues.
A. Cardin, H. Weintraub, Merrell Dow
semanticscholar   +1 more source

Glycosaminoglycans in Scleroderma and Scleredema

Journal of Investigative Dermatology, 1972
Skin from 6 patients with scleroderma, 3 with scleredema and 5 normal controls were subjected to qualitative and quantitative analysis of glycosaminoglycans. Glycosaminoglycans were identified by cetylpyridinium chloride-salt fractionation and by cellulose acetate electrophoresis.
Jerome S. Perlish, Raul Fleischmajer
openaire   +3 more sources

Advances in glycosaminoglycan detection

Molecular Genetics and Metabolism, 2020
Glycosaminoglycans (GAGs) are negatively charged long linear (highly sulfated) polysaccharides consisting of repeating disaccharide units that are expressed on the surfaces of all nucleated cells. The expression of GAGs is required for embryogenesis, regulation of cell growth and proliferation, maintenance of tissue hydration, and interactions of the ...
Hironori Kobayashi, Shunji Tomatsu, Robert W. Mason, Shaukat Khan, Seiji Yamaguchi   +4 more
openaire   +4 more sources

A Toxoplasma gondii thioredoxin with cell adhesion and antioxidant function

Frontiers in Cellular and Infection Microbiology
BackgroundToxoplasma gondii (T. gondii) is a widespread, zoonotic protozoan intracellular parasite with a complex life cycle, which can cause toxoplasmosis, a potentially serious disease. During the invasion process, T.
Dawei Wang, Dawei Wang, Yuyi Shi, Yuyi Shi, Ziwen Cheng, Ziwen Cheng, Like Luo, Like Luo, Kuo Cheng, Kuo Cheng, Shengqi Gan, Shengqi Gan, Che Liu, Che Liu, Zeliang Chen, Baoling Yang, Baoling Yang   +16 more
doaj   +1 more source