Results 81 to 90 of about 87,090 (247)

Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds

Cell Adhesion & Migration, 2010
Mean pore size is an essential aspect of scaffolds for tissue-engineering. If pores are too small cells cannot migrate in towards the center of the construct limiting the diffusion of nutrients and removal of waste products.
C. Murphy, F. O'Brien
semanticscholar   +1 more source

Home treatment of type VI mucopolysaccharidosis (Maroteaux‐Lamy syndrome) an alternative at this time of COVID‐19 pandemic: A case in Peru

Clinical Case Reports, 2020
We report a patient with mucopolysaccharidosis type VI, on long‐term enzyme replacement home therapy. Results support the efficacy and safety benefits, with additional advantage of home therapy to minimize the risk of community‐transmitted infections.
Jenny Lucy Cortez Miranda, Lincoln Blacido Trujillo, María Elena Liendo Chocano   +2 more
doaj   +1 more source

EXTL2, a Member of the EXT Family of Tumor Suppressors, Controls Glycosaminoglycan Biosynthesis in a Xylose Kinase-dependent Manner*

Journal of Biological Chemistry, 2013
Background: EXTL2 is one of three EXT-like genes homologous to the tumor suppressor EXT gene family members and encodes an N-acetylhexosaminyltransferase.
S. Nadanaka, Shaobo Zhou, Shoji Kagiyama, Naoko Shoji, K. Sugahara, Kazushi Sugihara, M. Asano, H. Kitagawa   +7 more
semanticscholar   +1 more source

Pathogens that infect mammalian cells via sulfonated glycosaminoglycans

Frontiers in Cellular and Infection Microbiology
Sulfonated glycosaminoglycans, such as heparan sulfate and dermatan sulfate, form major components of the cell surface and extracellular matrix, and display vital roles in mammalian physiology, including growth and development.
Jessica S. Morris, Paul A. Dawson
doaj   +1 more source

Could Biglycan be a biomarker of coronary artery disease? A pilot human study

Research in Cardiovascular Medicine, 2018
Background: Coronary artery calcification (CAC) is utilized as an important tool for the global risk assessment of cardiovascular events in individuals with intermediate risk.
Atefeh Rezapour, Maryam Moradian, Saeed Nazemi, Seyyed Adel Moallem, Sobhan Issazadeh, Sepideh Elyasi, Mohammad Afshar, Zahra Baghshani, Azadeh Zaerzadeh, Amir Hooshang Mohammadpour   +9 more
doaj   +1 more source

The Structural Elucidation of Glycosaminoglycans [PDF]

, 2008
There is accumulating evidence of the importance of linear polysaccharides in modulating biological phenomena in both the normal and the diseased states. This layer of regulation results from interactions between polysaccharides and other biomolecules, such as proteins, at the cell-extracellular matrix interface.
Vikas Prabhakar, Ishan Capila, Ram Sasisekharan   +2 more
openaire   +3 more sources

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

Frontiers in Immunology, 2018
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3).
Mieke Metzemaekers, Vincent Vanheule, Rik Janssens, Sofie Struyf, Paul Proost   +4 more
doaj   +1 more source

Heparan Sulfate: A Ubiquitous Glycosaminoglycan with Multiple Roles in Immunity

Frontiers in Immunology, 2013
Heparan sulfate (HS) is a highly acidic linear polysaccharide with a very variable structure. It is ubiquitously expressed on cell surfaces and in the extracellular matrix and basement membrane of mammalian tissues.
David Simon Davis, C. Parish
semanticscholar   +1 more source

Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds.

Tissue Engineering. Part A, 2011
Crosslinking and the resultant changes in mechanical properties have been shown to influence cellular activity within collagen biomaterials. With this in mind, we sought to determine the effects of crosslinking on both the compressive modulus of collagen-
M. Haugh, C. Murphy, R. C. McKiernan, Cornelia Altenbuchner, F. O'Brien   +4 more
semanticscholar   +1 more source

Some properties of testicular hyaluronidases

Mongolian Journal of Chemistry, 2014
The properties (pHopt, Topt, Km, temperature, acid and base stability of the enzyme activity) of hyaluronidase prepared from testes of bovine, horse, pig and antelope were determined.DOI: http://dx.doi.org/10.5564/mjc.v12i0.169 Mongolian Journal of ...
Ts Enkhmaa, D Purev, J Bayarmaa
doaj   +1 more source