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Chemoenzymatic Synthesis of Glycosaminoglycans.

Accounts of Chemical Research, 2019
Glycosaminoglycans (GAGs) are a family of structurally complex heteropolysaccharides composed of alternating hexosamine and uronic acid or galatose residue that include hyaluronan, chondroitin sulfate and dermatan sulfate, heparin and heparan sulfate ...
Xing Zhang   +3 more
semanticscholar   +1 more source

Sulfation of Glycosaminoglycans and Its Implications in Human Health and Disorders.

Annual Review of Biomedical Engineering, 2017
Sulfation is a dynamic and complex posttranslational modification process. It can occur at various positions within the glycosaminoglycan (GAG) backbone and modulates extracellular signals such as cell-cell and cell-matrix interactions; different ...
D. Soares da Costa   +2 more
semanticscholar   +1 more source

Glycosaminoglycans in Tendon Physiology, Pathophysiology, and Therapy.

Bioconjugate chemistry, 2015
Although glycosaminoglycans constitute a minor portion of native tissues, they play a crucial role in various physiological processes, while their abnormal expression is associated with numerous pathophysiologies.
Christina N. M. Ryan   +5 more
semanticscholar   +1 more source

A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures.

Connective Tissue Research, 1982
A rapid spectrophotometric procedure is described for the estimation of sulfated glycosaminoglycans in cartilage cultures. Papain digestion of tissue or culture medium provides glycosaminoglycans in solution for assay; an aliquot of the digest is mixed ...
R. Farndale, C. A. Sayers, A. J. Barrett
semanticscholar   +1 more source

Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes.

Physiological Reviews, 1991
Article de synthese sur les glycosaminoglycanes chez les mammiferes: proprietes et structure des proteoglycanes et des proteines de liaison des glycosaminoglycanes; roles dans la regulation des processus cellulaires et la regulation de l'expression des ...
R. Jackson, S. Busch, A. Cardin
semanticscholar   +1 more source

The GAGOme: a cell-based library of displayed glycosaminoglycans

Nature Methods, 2018
Yen-Hsi Chen   +16 more
semanticscholar   +1 more source

Glycosaminoglycans from marine sources as therapeutic agents.

Biotechnology Advances, 2017
J. Valcárcel   +4 more
semanticscholar   +1 more source

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