Results 241 to 250 of about 52,449 (293)

Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten   +4 more
wiley   +1 more source

Cellular and Matrix Organisation of the Human Aortic Valve Interleaflet Triangles. [PDF]

open access: yesBiology (Basel)
Latif N   +5 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro. [PDF]

open access: yesFEBS J
McEwan TB   +8 more
europepmc   +1 more source

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland   +9 more
wiley   +1 more source

Exploring relationships between tumor mutation burden with immunity and prognosis in lung adenocarcinoma based on weighted gene co‐expression network analysis

open access: yesPrecision Medical Sciences, EarlyView.
This study reveals that high TMB in lung adenocarcinoma correlates with better survival prognosis and lower immune/stromal scores. Through WGCNA and consensus clustering, we identify two LUAD subtypes with distinct prognoses and mutation frequencies, offering novel insights for immunotherapy response prediction and prognosis stratification.
Haiyong Wu   +7 more
wiley   +1 more source

Iterative Modeling via Structural Diffusion (IMSD): Exploring Fold‐Switching Pathways in Metamorphic Proteins Using AlphaFold2‐Based Generative Diffusion Model UFConf

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Metamorphic proteins (MPs) can fold into two or more distinct spatial structures. Increasing interest in MPs has spurred the search for computational tools to predict proteins fold‐switching potential and model their refolding pathways. Here we address this problem by using the recently reported generative diffusion predictor UFConf, based on ...
Dmitrii A. Luzik, Nikolai R. Skrynnikov
wiley   +1 more source

Home - About - Disclaimer - Privacy