Results 71 to 80 of about 16,712 (156)

Features of low-temperature storage of streptomyces strains - producers of glycosidaz inhibitors

Пищевые системы, 2019
The aim of the work is to study the inhibitory activity of the Streptomyces lucensis VKPM Ac-1743 and Streptomyces violaceus VKPM Ac-1734 strains stored at –18 °C in a 15 % glycerol solution and in a 0.9 % sodium chloride solution.The object of the study
A. A. Printseva, N. Yu. Sharova, T. V. Vybornova, B. S. Manzhieva   +3 more
doaj   +1 more source

Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents [PDF]

, 2016
To develop targeted methods for treating bacterial infections, the feasibility of using glycoside derivatives of the antibacterial compound L-R-aminoethylphosphonic acid (L-AEP) has been investigated.
Bovill, Richard, Evans, P. G., Howse, G. L., Osborn, Helen M. I.   +3 more
core   +1 more source

Design and synthesis of biologically active carbaglycosylamines: From glycosidase inhibitors to pharmacological chaperones. [PDF]

Proc Jpn Acad Ser B Phys Biol Sci, 2022
Ogawa S, Kuno S, Toyokuni T.
europepmc   +1 more source

Structure based virtual screening of natural product molecules as glycosidase inhibitors. [PDF]

In Silico Pharmacol, 2021
Moorthy NSHN, Brás NF, Ramos MJ, Fernandes PA.   +3 more
europepmc   +1 more source

Design and synthesis of phenoxymethybenzoimidazole incorporating different aryl thiazole-triazole acetamide derivatives as α-glycosidase inhibitors. [PDF]

Mol Divers, 2022
Nasli Esfahani A, Iraji A, Alamir A, Moradi S, Asgari MS, Hosseini S, Mojtabavi S, Nasli-Esfahani E, Faramarzi MA, Bandarian F, Larijani B, Hamedifar H, Hajimiri MH, Mahdavi M.   +13 more
europepmc   +1 more source

Regioselective fluorination in synthesis of deoxyfluoro quercitols from d-(−)-quinic acid [PDF]

[[abstract]]A facile synthesis of six new deoxyfluoro querciotls from d-(−)-quinic acid is described. The key steps involve the regioselective fluorination as well as highly stereoselective dihydroxylation.
[[corresponding]]Shih, Tzenge-Lien, Shih, Tzenge-Lien   +1 more
core   +1 more source

Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]

, 2016
Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith, Andriotis, Andriotis, Aoki, Asano, Asano, Bak-Jensen, Banik, Birte Svensson, Blackwell, Boisson, Burn, Burton, Burton, Chandrasekar, Chavez Montes, Comparot-Moss, Daussant, Dinges, Fincher, Finnie, Frandsen, Gibbons, Hatzfeld, Hickes, Holdsworth, Ichinose, Kihara, Kim, Kolodziejek, Lagaert, Lee, Lee, MacGregor, Martin Rejzek, Mega, Michael D. Rugen, Moreno-Risueno, Møller, Nash, O'Brien, Rejzek, Ritchie, Robert A. Field, Ruzanski, Sissons, Slade, Smith, Smith, Sonnewald, Soussillane, Stanley, Tanaka, Vasilios M. E. Andriotis, Vriet, Wheeler, Winchester, Zeeman   +57 more
core   +2 more sources

Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues

Molecules, 2019
Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14 ...
Qing-Kun Wu, Kyoko Kinami, Atsushi Kato, Yi-Xian Li, Yue-Mei Jia, George W. J. Fleet, Chu-Yi Yu   +6 more
doaj   +1 more source

Acarbose versus trans-chalcone: comparing the effect of two glycosidase inhibitors on obese mice

Archives of Endocrinology and Metabolism
Objective Acarbose and trans-chalcone are glucosidase inhibitors whose beneficial effects have been demonstrated in diabetes. The present study aimed at investigating their potential effects in obesity.Materials and methods NMRI male mice (n = 48) were ...
Fatemeh Jalalvand, Mahsa M. Amoli, Parichehreh Yaghmaei, Masoud Kimiagar, Azadeh Ebrahim-Habibi   +4 more
doaj   +1 more source

Biochemical Characterization of Diamide Inhibitors with N-acetylglucosaminidases LytG from Bacillus subtilis [PDF]

, 2016
In recent years the frequency of antibiotic resistance has been on the rise creating a need for antibiotic development with specific and lethal targets.
Phelan, Drew
core   +1 more source