Results 101 to 110 of about 17,138 (226)
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
Regulation of organelle pH by glycosphingolipids
Even though only about 5 mol% glycosphingolipids are found in cellular membranes, glycosphingolipids are essential during development, as a lack of these lipids was embryonically lethal in mice.
Chemistry Research: Bijvoet Centre for Biomolecular Research +3 more
core
ABSTRACT Natural antisense transcripts (NATs) correspond to nearly 60% of annotated rice loci, however their functions are largely unknown. In this study, we characterise a rice cis‐NAT (NAT1850) that completely overlaps with a rice‐specific primary miRNA, pri‐miR1850.
Yang Shen +11 more
wiley +1 more source
Glycosphingolipids Associated Metabolic Disorders
Lipids play diverse roles in sustaining life, including energy storage, hormonal balance, and cellular communication. Alterations in lipid metabolism can lead to various disorders, including diabetes, atherosclerosis, cancer, and neurodegenerative ...
Shakappa, Devindra, Jyoti, Prerna
core +1 more source
We have compared the domain forming properties of three neutral acyl chain defined glycosphingolipids differing in their head group structures. The aim of the study was to explore if glycosphingolipids and sterols exist in the same lateral domains in ...
Slotte, J. Peter +3 more
core +1 more source
Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA
Many bacterial toxins utilize cell surface glycoconjugate receptors for attachment to target cells. In the present study the potential carbohydrate binding of Helicobacter pylori vacuolating cytotoxin VacA was investigated by binding to human gastric ...
Barone, Silvia +5 more
core +1 more source
Helicobacter pylori SabA binding gangliosides of human stomach
Adhesion of Helicobacter pylori to the gastric mucosa is a prerequisite for the pathogenesis of H. pylori related diseases. In this study, we investigated the ganglioside composition of human stomach as the target for attachment mediated by H.
John Benktander +3 more
doaj +1 more source
Exploration into Galectin-3 Driven Endocytosis and Lattices
Essentially all plasma membrane proteins are glycosylated, and their activity is regulated by tuning their cell surface dynamics. This is achieved by glycan-binding proteins of the galectin family that either retain glycoproteins within lattices or drive
Massiullah Shafaq-Zadah +7 more
doaj +1 more source
Glycosphingolipids (GSLs) synthesized in Golgi apparatus by sequential transfer of sugar residues to a ceramide lipid anchor are ubiquitously distributing on vertebrate plasma membranes.
Midori Abe +2 more
core
This review explores the crucial role of glycosphingolipids (GSLs) in the context of cardiovascular diseases (CVDs), focusing on their biosynthesis, metabolic pathways, and implications for clinical outcomes.
Sarah Huang +2 more
doaj +1 more source

