Results 101 to 110 of about 18,580 (229)

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

The Crosstalk Between Glycosphingolipids And Neural Stem Cells [PDF]

open access: yes, 2019
Until a few years ago, the majority of cell functions were envisioned as the result of protein and DNA activity. The cell membranes were considered as a mere structure of support and/or separation.
Adami Raffaella   +2 more
core   +1 more source

Structure and biological functions of fungal cerebrosides

open access: yesAnais da Academia Brasileira de Ciências, 2004
Ceramide monohexosides (CMHs, cerebrosides) are glycosphingolipids composed of a hydrophobic ceramide linked to one sugar unit. In fungal cells, CMHs are very conserved molecules consisting of a ceramide moiety containing 9-methyl-4,8-sphingadienine in ...
Barreto-Bergter Eliana   +2 more
doaj  

Sphingolipid and ceramide associations with tau pathology vary across diverse ethnoracial groups in postmortem brain tissue

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Metabolic dysregulation is a hallmark of Alzheimer's disease (AD), with numerous studies characterizing metabolic pathways associated with AD onset and progression. A limitation of these studies has been a focus on non‐Hispanic white participants.
Annalise Schweickart   +19 more
wiley   +1 more source

Structures of glycosphingolipids cited in this study.

open access: yes, 2013
Symbols used for gangliosides and other glycosphingolipids are based on the system of Svennerholm and the nomenclature recommended by IUPAC.
Masaru Kubota (586022)   +5 more
core   +1 more source

Acetylation‐like H2BK109Q attenuates acute brain injury and preserves axon‐myelin integrity after intracerebral hemorrhage

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
After intracerebral hemorrhage, reduced pan‐H2B acetylation is linked to acute brain injury and axon–myelin damage. The acetylation‐mimetic H2BK109Q substitution attenuates injury and preserves axon–myelin integrity. Regional Galc knockdown diminishes this protection, identifying GALC as a primary contributing effector. ABSTRACT Aims Axon–myelin damage
Sinan Jin   +8 more
wiley   +1 more source

Graph attention network‐driven single‐cell omics analysis reveals how B4GALNT1‐mediated glycosylation remodelling of the ferroptosis–pyroptosis network promotes drug resistance in hepatocellular carcinoma

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Summary: B4GALNT1‐driven ganglioside/raft remodelling links ferroptosis suppression with restricted caspase‐1/GSDMD signalling during sorafenib resistance. Note: Schematic summary of the proposed B4GALNT1–ganglioside–lipid‐raft axis linking ferroptosis protection, restricted caspase‐1/GSDMD‐associated membrane permeabilisation, and sorafenib resistance.
Lihan Bie   +6 more
wiley   +1 more source

Discovery of Avian TCRVβ2+ T Cells Recognizing the Endogenous Ganglioside via a chCD1.1‐Dependent Pathway

open access: yesEuropean Journal of Immunology, Volume 56, Issue 10, October 2026.
We present the first report of chicken lipid‐reactive, NKT‐like TCRVβ2+ T cells that recognize the endogenous ganglioside GM3 presented by chCD1.1 on live antigen‐presenting cells. This activation induces a rapid cytokine response from avian lipid‐reactive T cells, offering a universal target for lipid‐adjuvanted poultry vaccines.
Nitin Kamble   +2 more
wiley   +1 more source

Helicobacter pylori SabA binding gangliosides of human stomach

open access: yesVirulence, 2018
Adhesion of Helicobacter pylori to the gastric mucosa is a prerequisite for the pathogenesis of H. pylori related diseases. In this study, we investigated the ganglioside composition of human stomach as the target for attachment mediated by H.
John Benktander   +3 more
doaj   +1 more source

Maturation‐Dependent Constraints in the Ability of Human Monocytes to Initiate Trained Immunity

open access: yesMedComm, Volume 7, Issue 10, October 2026.
In premature infants, innate immune memory may serve as an important compensatory mechanism for the underdeveloped adaptive immune system. However, monocytes derived from prematurely born individuals display abnormal metabolic and insufficient transcriptomic responses to β‐glucan‐induced training.
Michael Eigenschink   +10 more
wiley   +1 more source

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