Results 81 to 90 of about 18,580 (229)

Role of glycosphingolipids in formation and function of membrane microdomains

open access: yes, 2001
Recent years have been characterized by a huge interest in the structure and function of mammalian cell membrane lipid domains. The interest in this subject grew further, when their participation in important membrane-associated events such as signal ...
D. Ravasi   +5 more
core   +1 more source

Glycosphingolipids as Receptors for Non-Enveloped Viruses

open access: yes, 2010
Glycosphingolipids are ubiquitous molecules composed of a lipid and a carbohydrate moiety. Their main functions are as antigen/toxin receptors, in cell adhesion/recognition processes, or initiation/modulation of signal transduction pathways.
Christiane E. Wobus   +2 more
core   +2 more sources

Nephropathy in Fabry disease: possibilities for the radical improvement of prognosis for orphan diseases

open access: yesТерапевтический архив, 2013
The paper discusses the specific features of the diagnosis and treatment of kidney involvement in patients with Fabry disease.
V V Fomin, A A Pulin, N A Mukhin
doaj  

Atrial cardiomyopathy

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala   +1 more
wiley   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno   +3 more
wiley   +1 more source

Regulation of organelle pH by glycosphingolipids [PDF]

open access: yes, 2010
Even though only about 5 mol% glycosphingolipids are found in cellular membranes, glycosphingolipids are essential during development, as a lack of these lipids was embryonically lethal in mice.
Chemistry Research: Bijvoet Centre for Biomolecular Research   +3 more
core   +1 more source

Differences in the domain forming properties of N-palmitoylated neutral glycosphingolipids in bilayer membranes [PDF]

open access: yes, 2007
We have compared the domain forming properties of three neutral acyl chain defined glycosphingolipids differing in their head group structures. The aim of the study was to explore if glycosphingolipids and sterols exist in the same lateral domains in ...
Slotte, J. Peter   +3 more
core   +1 more source

Lysosomal storage diseases and the heat shock response: convergences and therapeutic opportunities

open access: yesJournal of Lipid Research, 2014
Lysosomes play a vital role in the maintenance of cellular homeostasis through the recycling of cell constituents, a key metabolic function which is highly dependent on the correct function of the lysosomal hydrolases and membrane proteins, as well as ...
Linda Ingemann, Thomas Kirkegaard
doaj   +1 more source

glycosphingolipid

open access: yes, 2014
Citation: 'glycosphingolipid' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02662 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Metabolic Profiling of Circulating and Tumour‐Infiltrating T Cells Uncovers Bioenergetic Checkpoints Linked With Immune and Clinical Skewing in Melanoma Patients

open access: yesImmunology, Volume 179, Issue 3, Page 486-515, November 2026.
In this study, we revealed the disturbed metabolic status of circulating and tumour‐infiltrating CD4+ and CD8+ T cells in melanoma patients through targeted metabolomic and lipidomic (on sorted subsets) and at single cell level using the SCENITH method.
Hugo Brouque   +11 more
wiley   +1 more source

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