Results 31 to 40 of about 36,633 (265)
New era of research on cancer‐associated glycosphingolipids
Cancer Science, 2019 Cancer‐associated glycosphingolipids have been used as markers for diagnosis and targets for immunotherapy of malignant tumors. Recent progress in the analysis of their implications in the malignant properties of cancer cells revealed that cancer ...
Kazuro Furukawa +8 more
semanticscholar +1 more source
Glycosphingolipids and lysosomal storage disorders as illustrated by gaucher disease.
Current Opinion in Chemical Biology, 2019 Glycosphingolipids are important building blocks of the outer leaflet of the cell membrane. They are continuously recycled, involving fragmentation inside lysosomes by glycosidases.
J. Aerts +6 more
semanticscholar +1 more source
A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation [PDF]
, 2016 Glycosylation greatly influences the safety and efficacy of many of the highest-selling recombinant therapeutic proteins (rTPs). In order to define optimal cell culture feeding strategies that control rTP glycosylation, it is necessary to know how ...
Jimenez del Val, I +2 more
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Glycosphingolipids and Infection. Potential New Therapeutic Avenues
Front. Cell Dev. Biol., 2019 Glycosphingolipids (GSLs), the main topic of this review, are a subclass of sphingolipids. With their glycans exposed to the extracellular space, glycosphingolipids are ubiquitous components of the plasma membrane of cells.
J. Aerts +4 more
semanticscholar +1 more source
eLife, 2018 Transport of biologically active molecules across tight epithelial barriers is a major challenge preventing therapeutic peptides from oral drug delivery.
M. Garcia-Castillo +11 more
semanticscholar +1 more source
Separation of neutral glycosphingolipids and sulfatides by thin-layer chromatography
Journal of Lipid Research, 1967 Two one-dimensional systems for separation of glycolipids from total lipid extracts of tissues by thin-layer chromatography are described. System I used, as adsorbent, an alkaline mixture of silica gel without CaSO4 binder (75%) and magnesium silicate ...
Vladimir P. Skipski +2 more
doaj +1 more source
Frontiers in Microbiology, 2021 Filamentous fungi are a group of economically important fungi used in the production of fermented foods, industrial enzymes, and secondary metabolites. Glycosphingolipids (GSLs) as constituents of lipid rafts are involved in growth, differentiation, and ...
Chunmiao Jiang +4 more
doaj +1 more source
Recent developments in the rapid analysis of plants and tracking their bioactive constituents [PDF]
, 2009 Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and LC/SPE/cryo-NMR, UHPLC, TLC/MS, MS-based preparative HPLC, comprehensive chromatography (GC × GC, LC
Beek, T.A., van +7 more
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Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer
Protein & Cell, 2020 Glycosylation is a common posttranslational modification on membrane-associated and secreted proteins that is of pivotal importance for regulating cell functions.
Jing Zhang +3 more
doaj +1 more source
Guillain-Barré syndrome: a century of progress [PDF]
, 2016 In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell +91 more
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