Results 31 to 40 of about 52,375 (251)

Locomotor hyperactivity in 14-3-3Zeta KO mice is associated with dopamine transporter dysfunction [PDF]

, 2013
Dopamine (DA) neurotransmission requires a complex series of enzymatic reactions that are tightly linked to catecholamine exocytosis and receptor interactions on pre- and postsynaptic neurons.
A Abi-Dargham, A Aitken, A Breier, A Vina-Vilaseca, AA Williams, AH Wong, B Giros, B Giros, BL Summers, BT Baune, C Itagaki, CA Tamminga, D Berg, D Sulzer, DL Levy, FA Middleton, H Fu, H Jaaro-Peled, H Khoshbouei, H Koike, HC Baxter, J Sun, J Wang, JA English, JA English, JA Lieberman, JA Lieberman, JH Son, JM van Rossum, K Toska, K Toyo-oka, K Toyo-Oka, KL Holton, M Laruelle, M Laruelle, M Miranda, M Rosner, M van den Buuse, M van den Buuse, MS Samuel, O Halskau Jr., P Coyle, PC Hart, PS Cheah, S Leucht, S Sivagnanasundaram, S Sivagnanasundaram, SG Amara, SR Jones, T Ichimura, T Ichimura, WC Drevets, WT Carpenter, Y Jia   +53 more
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Quantification of serum C-mannosyl tryptophan by novel assay to evaluate renal function and vascular complications in patients with type 2 diabetes

Scientific Reports, 2021
C-Mannosyl tryptophan (CMW) is a unique glycosylated amino acid, and a candidate novel biomarker of renal function. In type 2 diabetes (T2D), a combination of metabolites including CMW has recently been the focus of novel biomarkers for the evaluation of
Shuhei Morita, Yoko Inai, Shiho Minakata, Shohei Kishimoto, Shino Manabe, Naoyuki Iwahashi, Kazuhiko Ino, Yukishige Ito, Takashi Akamizu, Yoshito Ihara   +9 more
doaj   +1 more source

The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma [PDF]

, 2007
Aims: To clarify MUC1 patterns in invasive ductal breast carcinoma and to relate them to clinicopathological parameters, coexpression of other biological markers and prognosis.
Arnerlov C, Berry N, Camp RL, Croce MV, Gendler S, Gendler SJ, Hayes DF, Hilkens J, Kohlgraf KG, Ligtenberg MJ, Wesseling J   +10 more
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Vascular risk factors and diabetic neuropathy [PDF]

, 2005
Background: Other than glycemic control, there are no treatments for diabetic neuropathy. Thus, identifying potentially modifiable risk factors for neuropathy is crucial.
Chaturvedi, N., Eaton, S.E.M., Fuller, J.H., Ionescu-Tirgoviste, C., Manes, C., Tesfaye, S., Ward, J.D., Witte, D.R.   +7 more
core   +1 more source

Dysglycemia but not lipids is associated with abnormal urinary albumin excretion in diabetic kidney disease: a report from the Kidney Early Evaluation Program (KEEP) [PDF]

, 2012
BACKGROUND: The relationship between glycemic control and lipid abnormalities with urinary albumin-creatinine ratio (ACR) in chronic kidney disease (CKD) patients with diabetes mellitus (DM) is unknown.
Adam Whaley-Connell, Andrew S Bomback, Joseph Benjamin, Nehal N Mehta, null null, Peter A McCullough, Shu-Cheng Chen, Subhasish Bose, Suying Li   +8 more
core   +1 more source

Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum [PDF]

, 2015
The neuronal serpin neuroserpin undergoes polymerisation as a consequence of point mutations that alter its conformational stability, leading to a neurodegenerative dementia called familial encephalopathy with neuroserpin inclusion bodies (FENIB ...
Dalton, Lucy, Gooptu, Bibek, GUADAGNO, NOEMI ANTONELLA, Irving, James A, Lomas, David A, LUPO, GIUSEPPE, Manno, Mauro, Marciniak, Stefan J, Martorana, Vincenzo, MIRANDA BANOS, MARIA ELENA, MORICONI, CLAUDIA, Noto, Rosina, Ordoñez, Adriana, Timpano, Valentina   +13 more
core   +3 more sources

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival [PDF]

, 2014
Biomechanical strain imposed by age-related thickening of the basal lamina and augmented tissue stiffness in the prostate gland coincides with increased cancer risk. Here we hypothesized that the structural alterations in the basal lamina associated with
Breit, Claudia, Caley, Matthew P., Cox, Thomas R, Darby, Steven, Erler, Janine T, Gaughan, Luke, Gronau, Julian H., Mauri, Francesco, McCarthy, Afshan, Minamidate, Ai, Robson, Craig, Rodriguez-Teja, Mercedes, Sturge, Justin, Waxman, Jonathan, Zhang, Yu Zhi   +14 more
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Antidiabetic and antihyperlipidaemic activity of ethanol extract of Melastoma malabathricum Linn. leaf in alloxan induced diabetic rats

Asian Pacific Journal of Tropical Biomedicine, 2014
Objective: To evaluate the antidiabetic and antihyperlipidaemic effect of ethanol extract of Melastoma malabathricum (M. malabathricum) Linn. leaf in alloxan induced diabetic rats. Methods: Diabetes was induced in albino rats by administration of alloxan
Karuppasamy Balamurugan, Antony Nishanthini, Veerabahu Ramasamy Mohan   +2 more
doaj   +1 more source

Serum C-reactive protein and nutritional parameters in hemodialysis patients [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Inflammation is the most important factor in the genesis of vascular complication in the endstage renal disease. The serum C-reactive protein (CRP) level is a sensitive marker of systemic inflammation as well as a predisposing factor for ...
Dragović Tamara, Mijušković Mirjana, Terzić Brankica, Ristić-Medić Danijela, Hajduković Zoran, Rađen Slavica   +5 more
doaj   +1 more source

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates [PDF]

, 2014
Since its discovery and isolation, exogenous insulin has dramatically changed the outlook for patients with diabetes. However, even when patients strictly follow an insulin regimen, serious complications can result as patients experience both ...
Anderson, Daniel Griffith, Chou, Danny Hung-Chieh, Cortinas, Abel Bryan, Deng, David, Langer, Robert S, Lin, Amy B., Tang, Benjamin C., Thapa, Lavanya S., Truong, Jonathan V., Webber, Matthew   +9 more
core   +1 more source