Results 81 to 90 of about 41,434 (212)

Alternaria alternata Effector Aa593 Promotes Virulence by Hijacking the CmNAC29‐Mediated Abscisic Acid Biosynthesis Pathway in Chrysanthemum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The interaction between plants and pathogens has long been an actively researched field of plant immunity. In this study, we found an Aa593/CmNAC29‐CmNCED3 module associated with the interaction between chrysanthemum and the fungal pathogen Alternaria alternata.
Boxiao Dong   +10 more
wiley   +1 more source

TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han   +14 more
wiley   +1 more source

Data for identification of GPI-anchored peptides and ω-sites in cancer cell lines

open access: yesData in Brief, 2016
We present data obtained using a focused proteomics approach to identify the glycosylphosphatidylinositol (GPI)-anchored peptides in 19 human cancer cell lines.
Yusuke Masuishi   +3 more
doaj   +1 more source

Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation

open access: yesNature Communications, 2020
Glycosylphosphatidylinositol (GPI) anchors are found on many cell surface proteins but their biosynthesis is not fully understood. Here, the authors identify genes involved in GPI galactosylation and reveal functional connections between GPI processing ...
Yicheng Wang   +8 more
doaj   +1 more source

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain. [PDF]

open access: yes, 2016
GPIHBP1 is a glycolipid-anchored membrane protein of capillary endothelial cells that binds lipoprotein lipase (LPL) within the interstitial space and shuttles it to the capillary lumen.
Beigneux, Anne P   +9 more
core   +4 more sources

Compound Heterozygosity in PGAP3 Causing Mabry Syndrome in a South African Patient

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Carli Loubser, Shahida Moosa
wiley   +1 more source

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk   +15 more
wiley   +1 more source

Biallelic mutations in PIGP cause developmental and epileptic encephalopathy

open access: yesAnnals of Clinical and Translational Neurology, 2019
Developmental and epileptic encephalopathies are characterized by infantile seizures and psychomotor delay. Glycosylphosphatidylinositol biosynthesis defects, resulting in impaired tethering of various proteins to the cell surface, represent the ...
Martin Krenn   +10 more
doaj   +1 more source

Biomedical applications of glycosylphosphatidylinositol-anchored proteins

open access: yesJournal of Lipid Research, 2016
Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) use a unique posttranslational modification to link proteins to lipid bilayer membranes. The anchoring structure consists of both a lipid and carbohydrate portion and is highly conserved in ...
Susanne Heider   +2 more
doaj   +1 more source

Targeting of the prion protein to the cytosol: mechanisms and consequences

open access: yes, 2010
Prion diseases are characterized by the conformational transition of the cellular prion protein (PrPC) into an aberrant protein conformer, designated scrapie-prion protein (PrPSc).
Miesbauer, M.   +3 more
core  

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