Results 81 to 90 of about 829,091 (166)

Kisspeptin Resets the Hypothalamic GnRH Clock in Men

, 2011
Context: Reproduction in all mammals is controlled by a hypothalamic clock that produces periodic secretory pulses of GnRH, but how the timing of these pulses is determined is poorly understood.
Yee-Ming Chan, François P. Pralong, Stephanie B. Seminara, Chen Ren, James P. Butler, Kenneth K. Chan, William F. Crowley, Nancy E. Pinnell   +7 more
core   +1 more source

The Effects of gonadotropin-releasing hormone analog and a combination of gonadotropin-releasing hormone analog and recombinant human growth hormone on adult height in girls with early puberty

Advanced Biomedical Research, 2019
Background: Early puberty (EP) is due to the activation of gonadotropin-releasing hormone (GnRH) pulse generator in lower ages; EP may be a potential cause for impairment of adult height, leading to short stature.
Ghodsieh Hajzadeh, Norsrat Ghaemi, Mousa-Al-Reza Hadjzadeh, Samaneh Noroozi, Negar Morovatdar   +4 more
doaj   +1 more source

Periestropause enhances hypoxia‐induced panic and microglial remodelling without altering respiratory control

Journal of Neuroendocrinology, Volume 38, Issue 9, September 2026.
Abstract Perimenopause is characterised by irregular reproductive cycles and hormonal fluctuations, notably decreased estradiol (E2), which are linked to increased susceptibility to panic disorder and neuroinflammation. We examined whether panic‐related respiratory and behavioural responses to respiratory challenges vary across reproductive stages ...
Angela Cristina Nicola, Luana Tenório‐Lopes, Luis Gustavo A. Patrone, Mariana Bernardes‐Ribeiro, Heloisa H. Vilela‐Costa, Daniele Gandra, Ana Clara Campideli‐Santana, Raphael E. Szawka, Kênia C. Bícego, Rita Cássia M. Dornelles, Luciane H. Gargaglioni   +10 more
wiley   +1 more source

The control of the gonadotrophin releasing hormone pulse generator in relation to opioid and nutritional cues.

, 2016
Human fertility is ultimately dependent upon the regular pulsatile release of gonadotrophin releasing hormone (GnRH) from hypothalamic neurons. The GnRH pulse generator is subject to modulation by a variety of substances, some of which reflect the ...

core   +1 more source

Melatonin effects on luteinizing hormone in postmenopausal women: a pilot clinical trial NCT00288262

BMC Women's Health, 2006
Background In many mammals, the duration of the nocturnal melatonin elevation regulates seasonal changes in reproductive hormones such as luteinizing hormone (LH). Melatonin's effects on human reproductive endocrinology are uncertain.
Kline Lawrence E, Kripke Daniel F, Shadan Farhad F, Dawson Arthur, Poceta J Steven, Elliott Jeffrey A   +5 more
doaj   +1 more source

Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat

, 2001
Phytoestrogens can produce inhibitory effects on gonadotropin secretion in both animals and humans. The aims of this study were 2-fold: 1) to determine in vivo whether genistein and coumestrol act on the GnRH pulse generator to suppress hypothalamic ...
McGarvey, C, Cates, P S, Coen, C W; id_orcid, O'Byrne, K T, Swanson, I A, Milligan, S R, Brooks, A N, C. McGarvey   +7 more
core   +1 more source

Genetics of Idiopathic Hypogonadotropic Hypogonadism

JCRPE
Idiopathic hypogonadotropic hypogonadism (IHH) comprises a group of disorders characterized by deficient secretion or action of gonadotropin-releasing hormone (GnRH), leading to impaired pubertal development and infertility.
A. Kemal Topaloğlu, Leman Damla Kotan
doaj   +1 more source

Review of the Literature on Current Changes in the Timing of Pubertal Development and the Incomplete Forms of Early Puberty

Frontiers in Pediatrics, 2019
Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys.
Giovanni Farello, Carla Altieri, Maristella Cutini, Gabriella Pozzobon, Alberto Verrotti   +4 more
doaj   +1 more source

Puberty and type 1 diabetes

Indian Journal of Endocrinology and Metabolism, 2015
Various data on type 1 diabetes mellitus (T1DM) have showed that the incidence of T1DM peaks at puberty. However, diabetes control and complications could be adversely affected by the physiological changes of puberty.
Subhankar Chowdhury
doaj   +1 more source

Gonadotropin-Releasing Hormone (GnRH) Pulse Pattern Regulates GnRH Receptor Gene Expression: Augmentation by Estradiol

, 1995
GnRH acts via a single cell surface receptor (GnRH-R), and the number of pituitary GnRH-R increases on proestrus, after gonadectomy, or in response to pulsatile GnRH in the rat.
Haisenleder, D. J., Kerrigan, J. R., Marshall, J. C., Yasin, M., Dalkin, A. C.   +4 more
core   +1 more source