Results 41 to 50 of about 328,019 (196)

Use of hamster as a model to study diet-induced atherosclerosis

open access: yesNutrition & Metabolism, 2010
Golden-Syrian hamsters have been used as an animal model to assess diet-induced atherosclerosis since the early 1980s. Advantages appeared to include a low rate of endogenous cholesterol synthesis, receptor-mediated uptake of LDL cholesterol, cholesteryl
Lichtenstein Alice H   +2 more
doaj   +1 more source

Dibutylnitrosamine Carcinogenesis in Syrian Golden and Chinese Hamsters

open access: yesExperimental Biology and Medicine, 1971
SummaryComparative studies with Syrian Golden and Chinese hamsters after intragastric and subcutaneous treatment with dibutylnitrosamine are reported. In both species morphologically similar tumors of the urinary bladder, forestomach, oral, and nasal cavities occurred.
J, Althoff   +3 more
openaire   +2 more sources

Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal

open access: yesFrontiers in Behavioral Neuroscience, 2021
The endocannabinoid system modulates epileptic seizures by regulating neuronal excitability. It has become clear that agonist activation of central type I cannabinoid receptors (CB1R) reduces epileptogenesis in pre-clinical animal models of epilepsy. The
Alejando Fuerte-Hortigón   +14 more
doaj   +1 more source

Diet-induced obesity and hypercholesterolemia in the Golden Syrian hamster.

open access: yes, 2015
Whole-body fat mass (g), free-fed blood lipid and insulin levels of hamsters fed high fat-high carbohydrate (HPFS) palatable diet with 0.5% cholesterol supplementation for 12 weeks.
Louise S. Dalbøge (420563)   +6 more
core   +1 more source

Bio F1B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism

open access: yesNutrition & Metabolism, 2007
Background Bio F1B hamster is an inbred hybrid strain that is highly susceptible to diet-induced atherosclerosis. We previously reported that feeding a high fat fish oil diet to Bio F1B hamster caused severe hyperlipidaemia. In this study we compared the
Cornish Marion L, Cheema Sukhinder
doaj   +1 more source

Social context modulates food hoarding in Syrian hamsters

open access: yesInternational Journal of Psychological Research, 2016
The effect of the presence of a con-specific in the temporal organization of food hoarding was studied in two varieties of Syrian hamster (Mesocricetus auratus): golden and long-haired. Four male hamsters of each variety were used.
Bibiana Montoya, Germán Gutiérrez
doaj   +3 more sources

Evaluation of Immunogenicity and Clinical Protection of SARS-CoV-2 S1 and N Antigens in Syrian Golden Hamster

open access: yesVaccines, 2022
The novel coronavirus (SARS-CoV-2) epidemic continues to be a global public crisis affecting human health. Many research groups are developing different types of vaccines to suppress the spread of SARS-CoV-2, and some vaccines have entered phase III ...
Zhenye Niu   +13 more
doaj   +1 more source

Validation of Stable Housekeeping Genes for Quantitative Real Time PCR in Golden Syrian Hamster

open access: yes, 2020
Background: Golden Syrian hamster (GSH) have many advantages as animal models in preclinical research, but their application is currently limited by the lack of standardized techniques for analyzing gene expression.
Peng, Ying   +17 more
core   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

open access: yesAdvanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun   +13 more
wiley   +1 more source

The ventral striatum of the Syrian hamster

open access: yes, 1999
The Syrian hamster, Mesocricetus auratus, was first used in laboratory experiments some fifty years ago in the Middle East, from animals captured in the wild.
LUKE R. JOHNSON   +3 more
core   +1 more source

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