Results 41 to 50 of about 7,779 (200)

Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system. [PDF]

PLoS ONE, 2014
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research.
Zhiqiang Fan, Wei Li, Sang R Lee, Qinggang Meng, Bi Shi, Thomas D Bunch, Kenneth L White, Il-Keun Kong, Zhongde Wang   +8 more
doaj   +1 more source

Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters

Microbiology Spectrum, 2023
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible respiratory pathogen whose main transmission route is respiratory droplets and/or aerosols.
Philip J. Kuehl, Justin Dearing, Adam Werts, Jason Cox, Hammad Irshad, Edward G. Barrett, Sean N. Tucker, Stephanie N. Langel   +7 more
doaj   +1 more source

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]

, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
R. R. Shen, O'Donovan, MRO, P. L. Carmichael, Schechtman, LM, Aardema, MJ, M. J. Aardema, Tanaka, N, K. Pant, Sakai, A, Scott, AD, Shen, RR, S. Creton, A. Poth, Harvey, JS, Pant, K, M. R. O'Donovan, Creton, S, A. D. Scott, R. F. Newbold, J. S. Harvey, L. M. Schechtman, N. Tanaka, K. Sasaki, Newbold, RF, Yasaei, H, Poth, A, Sasaki, K, A. Sakai, Martin, FL, F. L. Martin, Carmichael, PL, H. Yasaei   +31 more
core   +1 more source

Use of hamster as a model to study diet-induced atherosclerosis

Nutrition & Metabolism, 2010
Golden-Syrian hamsters have been used as an animal model to assess diet-induced atherosclerosis since the early 1980s. Advantages appeared to include a low rate of endogenous cholesterol synthesis, receptor-mediated uptake of LDL cholesterol, cholesteryl
Lichtenstein Alice H, Matthan Nirupa R, Dillard Alice   +2 more
doaj   +1 more source

An immunosuppressed Syrian golden hamster model for SARS-CoV infection [PDF]

, 2008
Several small animal models have been developed for the study of severe acute respiratory syndrome coronavirus (SARS-CoV) replication and pathogenesis. Syrian golden hamsters are among the best small animal models, though little clinical illness and no ...
Oberle, Christina, Sagartz, John E., Jennifer Stabenow, R. Mark Buller, Pekosz, Andrew, Schriewer, Jill, Jill Schriewer, Scott R. Schaecher, Andrew Pekosz, John E. Sagartz, Stabenow, Jennifer, Schaecher, Scott R., Christina Oberle, Buller, R. Mark   +13 more
core   +1 more source

Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal

Frontiers in Behavioral Neuroscience, 2021
The endocannabinoid system modulates epileptic seizures by regulating neuronal excitability. It has become clear that agonist activation of central type I cannabinoid receptors (CB1R) reduces epileptogenesis in pre-clinical animal models of epilepsy. The
Alejando Fuerte-Hortigón, Alejando Fuerte-Hortigón, Jaime Gonçalves, Jaime Gonçalves, Jaime Gonçalves, Laura Zeballos, Laura Zeballos, Laura Zeballos, Rubén Masa, Ricardo Gómez-Nieto, Ricardo Gómez-Nieto, Ricardo Gómez-Nieto, Dolores E. López, Dolores E. López, Dolores E. López   +14 more
doaj   +1 more source

Bio F₁B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism

Nutrition & Metabolism, 2007
Background Bio F1B hamster is an inbred hybrid strain that is highly susceptible to diet-induced atherosclerosis. We previously reported that feeding a high fat fish oil diet to Bio F1B hamster caused severe hyperlipidaemia. In this study we compared the
Cornish Marion L, Cheema Sukhinder
doaj   +1 more source

Dibutylnitrosamine Carcinogenesis in Syrian Golden and Chinese Hamsters

Experimental Biology and Medicine, 1971
SummaryComparative studies with Syrian Golden and Chinese hamsters after intragastric and subcutaneous treatment with dibutylnitrosamine are reported. In both species morphologically similar tumors of the urinary bladder, forestomach, oral, and nasal cavities occurred.
J, Althoff, F W, Krüger, U, Mohr, D, Schmahl   +3 more
openaire   +2 more sources

Social context modulates food hoarding in Syrian hamsters

International Journal of Psychological Research, 2016
The effect of the presence of a con-specific in the temporal organization of food hoarding was studied in two varieties of Syrian hamster (Mesocricetus auratus): golden and long-haired. Four male hamsters of each variety were used.
Bibiana Montoya, Germán Gutiérrez
doaj   +3 more sources

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

Animal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong, Ning Liu, Weining Kong, Xiang Gao, Feifei Guan, Shan Gao, Yuanwu Ma   +6 more
wiley   +1 more source