Application of EGFR-TKIs in brain tumors, a breakthrough in future? [PDF]
Feng S, Liu H, Yun C, Zhu W, Pan Y.
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GOLPH3 inhibits erastin‐induced ferroptosis in colorectal cancer cells
Cell Biology InternationalFerroptosis is a novel form of programmed cell death and is considered to be a druggable target for colorectal cancer (CRC) therapy. However, the role of ferroptosis in CRC and its underlying mechanism are not fully understood.
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Molecular and Cellular EndocrinologyOvarian cancer stands as a formidable clinical challenge, with limited therapeutic options. This investigation delves into the intricate molecular mechanisms governing ovarian cancer progression and uncovers Centromere Protein K (CENPK) as a central ...
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GOLPH3 Promotes Vascular Mimicry via the Epithelial Mesenchymal Transition in Glioblastoma Cells.
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Molecular Regulation and Physiological Role of GOLPH3-mediated Golgi retention
AbstractThe Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long been debated. Recent studies have identified a molecular machinery that sorts resident proteins into retrograde-directed COPI vesicles during ...
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Journal of Molecular Neuroscience, 2020We aimed to examine whether golgi protein GOLPH3 could affect the secretion of glioma cell-derived exosomes. The exosomes were extracted by ultra-centrifugation from the supernatant of U251 and U87 cell cultures and identified by transmission electron microscopy (TEM), Malvern analyzer, and western blot.
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