Effect of GOLPH3 on cumulus granulosa cell apoptosis and ICSI pregnancy outcomes [PDF]
Scientific Reports, 2017 Previous studies have shown that GOLPH3 mediates cell growth, proliferation and differentiation and inhibits cell apoptosis; however, the role of GOLPH3 in cumulus granulosa cells and the value of GOLPH3 in predicting ICSI pregnancy outcomes remain ...
Dianliang Lin +7 more
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Identification of the client-binding site on the Golgi membrane protein adaptor Vps74/yGOLPH3 [PDF]
iScienceSummary: Vps74 and its mammalian counterpart GOLPH3 are COPI associated protein sorting adaptors that function to maintain the cisternal distributions of a diversity of Golgi integral membrane protein clients by binding to their short cytoplasmically ...
Agnieszka M. Lesniak +2 more
doaj +2 more sources
Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster [PDF]
Open Biology, 2017 Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is
Stefano Sechi +8 more
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GOLPH3 and GOLPH3L maintain Golgi localization of LYSET and a functional mannose 6-phosphate transport pathway. [PDF]
EMBO JBrauer BK +18 more
europepmc +2 more sources
Golgicide A induces pyroptosis of lung cancer stem cells by regulating dTGN formation via GOLPH3/MYO18A complex [PDF]
Stem Cell Research & TherapyBackground Lung cancer is a common malignant neoplasm, one of the leading causes of death worldwide. Cancer stem cells (CSCs) drive tumor recurrence, progression, and therapeutic resistance.
Feng Zhang +10 more
doaj +2 more sources
MiR-1/GOLPH3/Foxo1 Signaling Pathway Regulates Proliferation of Bladder Cancer [PDF]
Technology in Cancer Research & Treatment, 2019 Objective: To investigate role of microRNA-1/Golgi phosphoprotein 3/Foxo1 axis in bladder cancer. Methods: The expression of Golgi phosphoprotein 3 was determined in both bladder cancer tissues and cell lines using quantitative real-time polymerase chain reaction and Western blotting, respectively.
Mingkai Liu +6 more
openalex +3 more sources
Golgi phosphoprotein 3 (GOLPH3); mammalian target of rapamycin (mTOR; FRAP; RAFT1) [PDF]
Science-Business eXchange, 2009 openalex +2 more sources
GOLPH3 modulates expression and alternative splicing of transcription factors associated with endometrial decidualization in human endometrial stromal cells [PDF]
PeerJ, 2023 Endometrial decidualization is a decidual tissue formed by the proliferation and re-differentiation of endometrial stroma stimulated by decidualization inducing factors. It is very important for the proper maintenance of pregnancy.
Suqin Zhu +7 more
doaj +2 more sources
GOLPH3L antagonizes GOLPH3 to determine Golgi morphology
Molecular Biology of the Cell, 2013 GOLPH3 is a phosphatidylinositol-4-phosphate (PI4P) effector that plays an important role in maintaining Golgi architecture and anterograde trafficking. GOLPH3 does so through its ability to link trans-Golgi membranes to F-actin via its interaction with myosin 18A (MYO18A).
Michelle M. Ng +4 more
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Roles of GOLPH3, a PI(4)P binding protein, in the physiopathology of cancer [PDF]
International Journal of Molecular Sciences, 2020 Golgi phosphoprotein 3 (GOLPH3), a Phosphatidylinositol 4-Phosphate [PI(4)P] effector at the Golgi, is required for Golgi ribbon structure maintenance, vesicle trafficking and Golgi glycosylation. GOLPH3 has been validated as an oncoprotein through combining integrative genomics with clinopathological and functional analyses. It is frequently amplified
Maria Grazia Giansanti +4 more
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