Results 71 to 80 of about 2,350 (202)
Golgi maturation‐dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3
The EMBO Journal, 2021 Glycosphingolipids are important components of the plasma membrane where they modulate the activities of membrane proteins including signalling receptors. Glycosphingolipid synthesis relies on competing reactions catalysed by Golgi-resident enzymes during the passage of substrates through the Golgi cisternae.Rizzo, Riccardo, Russo, Domenico, Kurokawa, Kazuo, Sahu, Pranoy, Lombardi, Bernadette, Supino, Domenico, Zhukovsky, Mikhail, Vocat, Anthony, Pothukuchi, Prathyush, Kunnathully, Vidya, Capolupo, Laura, Boncompain, Gaelle, Vitagliano, Carlo, Zito Marino, Federica, Aquino, Gabriella, Montariello, Daniela, Henklein, Petra, Mandrich, Luigi, Botti, Gerardo, Clausen, Henrik, Mandel, Ulla, Yamaji, Toshiyuki, Hanada, Kentaro, Budillon, Alfredo, Perez, Franck, Parashuraman, Seetharaman, Hannun, Yusuf, Nakano, Akihiko, Corda, Daniela, D’angelo, Giovanni, Luini, Alberto +30 moreopenaire +6 more sourcesGenomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]
, 2018 This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing
molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...Abdel-Rahman, Mohamed H., Abeshouse, Adam, Adebamowo, Clement, Adebamowo, Sally N., Agnew, Kathy, Ahn, Keunsoo, Ajani, Jaffer A., Akbani, Rehan, Akbani, Rehan, Akeredolu, Teniola, Al-Ahmadie, Hikmat, Al-Ahmadie, Hikmat, Albert, Monique, Alexopoulou, Iakovina, Ally, Adrian, Alvaro, Domenico, Anderson, Matthew L., Andry, Chris, Antenucci, Anna, Anur, Pavana, Anur, Pavana, Appelbaum, Elizabeth L., Aredes, Natália D., Armenia, Joshua, Arnaout, Angel, Asa, Sylvia L., Auman, J. Todd, Aymerich, Marta, Aziz, Dina, Bailey, Matthew, Balasundaram, Miruna, Balu, Saianand, Barnett, Gene, Barnholtz-Sloan, Jill S., Barrett, Wendi, Bartlett, John, Bathe, Oliver, Baudin, Eric, Baylin, Stephen, Becker, Karl-Friedrich, Beer, David, Behera, Madhusmita, Behrens, Carmen, Bell, Debra, Bell, Sue, Bellair, Michelle, Bennett, Joseph, Benz, Christopher, Benz, Christopher, Berchuck, Andrew, Berger, Ashton C., Bergeron, Alain, Berkowitz, Ross, Bernard, Brady, Beroukhim, Rameen, Beuschlein, Felix, Bifulco, Carlo, Bigner, Darell, Birrer, Michael, Birsoy, Kivanc, Bocklage, Therese, Bodenheimer, Tom, Bondaruk, Jolanta, Bootwalla, Moiz S., Borad, Mitesh, Borgia, Jeffrey A., Bossler, Aaron, Botnariuc, Natalia, Boussioutas, Alex, Bowen, Jay, Bowlby, Reanne, Bowlby, Reanne, Bowman, Rayleen, Bradford, Carol, Bragazzi, Maria Consiglia, Brat, Daniel J., Breggia, Anne, Brennan, Kevin, Brewer, Cathy, Brimo, Fadi, Broaddus, Russell, Brooks, Denise, Broom, Bradley M., Broudy, Thomas, Bryce, Alan H., Bubley, Glenn, Bueno, Raphael, Bullman, Susan, Burnette, Andrew, Byers, Lauren Averett, Caesar-Johnson, Samantha J., Calatozzolo, Chiara, Campbell, Joshua D., Campo, Elias, Campos, Benito, Caraman, Irina, Cardinale, Vincenzo, Carey, Francis, Carey, Thomas, Carlotti, Carlos Gilberto, Carlsen, Rebecca, Carney, Michael, Carpino, Guido, Carroll, Peter R., Carter, Candace, Carvalho, Andre L., Castle, Erik, Castro, Patricia D., Catto, James, Cebulla, Colleen M., Cernat, Mircea, Chabot, John, Chakravarty, Debyani, Chambwe, Nyasha, Chan, June M., Chan, Timothy A., Chandan, Vishal, Chang, Kyle, Chatila, Walid K., Chemencedji, Inga, Chen, Amy, Chen, Chu, Chen, Jianhong, Chen, Ting-Wen, Chen, Zhong, Cheng, Feixiong, Cheng, Hui, Cherniack, Andrew D., Cherniack, Andrew D., Chesla, David, Chevalier, Simone, Cheville, John, Chiu, Hua-Sheng, Cho, Juok, Chuah, Eric, Chudamani, Sudha, Chung, Ki, Cibulskis, Carrie, Clipca, Adrian, Coarfa, Cristian, Colman, Howard, Cope, Leslie, Copland, John A., Corcoran, Niall, Cordes, Matthew G., Costello, Tony, Cottingham, Sandra, Couce, Marta, Covington, Kyle, Crain, Daniel, Cramer, Daniel, Creaney, Jenette, Creighton, Chad J., Creighton, Chad J., Cuppini, Lucia, Curley, Erin, Cuzzubbo, Stefania, Czerniak, Bogdan, Danilova, Ludmila, Davis, Amy, de Bruijn, Ino, de Carvalho, Ana C., de Krijger, Ronald, De Rienzo, Assunta, De Rose, Agostino, Defreitas, Timothy, Delman, Keith, Demchok, John A., Desjardins, Laurence, Devine, Karen, Deyarmin, Brenda, Dhalla, Noreen, Dhanasekaran, Renumathy, Dhankani, Varsha, Dhir, Rajiv, Diao, Lixia, Dimeco, Francesco, Ding, Li, Dinh, Huyen, Dinkin, Mikhail, Dipersio, John, Disaia, Philip, Doddapaneni, Harshavardhan, Donehower, Larry, Donehower, Lawrence A., Doruc, Serghei, Dos Santos, Jose Sebastião, Dottino, Peter R., Drake, Bettina, Drill, Esther, Drummond, Jennifer, Drwiega, Paul, Dubina, Michael, Duell, Rebecca, Duffy, Elizabeth R., Eckman, John, Edenfield, W. Jeffrey, Eijckenboom, Wil, Elder, J. Bradley, Engel, Jay, Eschbacher, Jennifer, Esmaeli, Bita, Evason, Kimberley, Facciolo, Francesco, Fan, Cheng, Fan, Huihui, Fan, Huihui, Fantacone-Campbell, J. Leigh, Farnell, Michael, Farver, Carol, Fassnacht, Martin, Fehrenbach, Ashley, Felau, Ina, Feldman, Michael, Feltmate, Colleen, Ferguson, Martin L., Finocchiaro, Gaetano, Flores, Elsa R., Flotte, Thomas, Fong, Kwun M., Force, Seth, Forgie, Ian, Frazer, Scott, Fregnani, José H., Fronick, Catrina C., Fujimoto, Junya, Fulop, Jordonna, Fulton, Lucinda A., Fulton, Robert S., Gabra, Hani, Gabriel, Stacey B., Galbraith, Joseph, Gao, Galen F., Gao, Jianjiong, Gardner, Johanna, Gastier-Foster, Julie M., Gaudio, Eugenio, Gay, Carl M., Gehlenborg, Nils, Gerken, Mark, Gershenwald, Jeffrey, Getz, Gad, Gevaert, Olivier, Ghossein, Ronald, Giama, Nasra, Gibbs, Richard A., Gilbert, Sebastien, Gillis, Ad, Gimenez-Roqueplo, Anne-Paule, Giné, Eva, Giordano, Thomas, Girard, Nicolas, Giuliante, Felice, Glenn, Pat, Glenn, Robert, Godwin, Andrew K., Godwin, Eryn M., Gonzalez, Ana Maria Angulo, Goodman, Marc, Gopalan, Anuradha, Goparaju, Chandra, Gorincioi, Ghenadie, Govindan, Ramaswamy, Graefen, Markus, Grazi, Gianluca, Grizzle, William E., Gross, Benjamin E., Guillermo, Armando López, Gunaratne, Preethi, Guo, Charles, Ha, Gavin, Haddad, Andrea, Hagedorn, Curt H., Hale, Walker, Han, Yi, Hanh, Phan Thi, Hansen, Paul, Harr, Jodi, Hartmann, Arndt, Haydu, Lauren, Hayes, D. Neil, Hayes, D. Neil, Hayward, Nicholas, Heath, Sharon, Hegde, Apurva, Hegde, Apurva M., Heiman, David I., Heins, Zachary J., Henderson, Joel, Hermes, Beth, Hernandez, Brenda, Herold-Mende, Christel, Hersey, Peter, Hess, Julian, Hibshoosh, Hanina, Hilty, Joe, Hinoue, Toshinori, Ho, Thai, Hoadley, Katherine A., Hoadley, Katherine A., Holt, Robert, Hooke, Jeffrey A., Hoon, Dave, Horowitz, Neil, Houck, John, Hovens, Christopher, Hoyle, Alan P., Hu, Hai, Hu, Jianhong, Huland, Hartwig, Hung, Nguyen Phi, Huntsman, David, Hutter, Carolyn M., Iacocca, Mary, Ittmann, Michael, Jacobus, Laura, Jakrot, Valerie, Janssen, Klaus-Peter, Jefferys, Stuart R., Jimeno, Antonio, Jones, Corbin D., Jones, Steven J. M., Ju, Zhenlin, Juhl, Hartmut, Jungk, Christin, Junker, Kerstin, Kakavand, Hojabr, Kalkanis, Steven, Kanchi, Rupa S., Kanchi, Rupa S., Kandoth, Cyriac, Kang, Koo Jeong, Karlan, Beth Y., Kasaian, Katayoon, Kasapi, Melpomeni, Kastl, Alison, Kebebew, Electron, Kefford, Richard, Kelley, Robin K., Kemp, Rafael, Kendall, Sara, Kendler, Ady, Kendrick, Michael, Khuri, Fadlo, Kibel, Adam, Kim, Jaegil, Knijnenburg, Theo, Knudson, Michael, Knutson, Tina, Kocher, Jean-Pierre, Kohl, Bernard, Kopp, Karla, Korchina, Viktoriya, Korkut, Anil, Korpershoek, Esther, Korst, Robert, Kovatich, Albert J., Kramer, Roger, Kucherlapati, Melanie H., Kucherlapati, Raju S., Kumar, Bahavna, Kundra, Ritika, Kvecher, Leonid, Kycler, Witold, La, Konnor, Lacombe, Louis, Ladanyi, Marc, Lai, Phillip H., Laird, Peter W., Laird, Peter W., Landen, Charles N., Landrum, Lisa, Lang, James, Larson, Caroline, Latour, Mathieu, Lau, Kevin, Lawrence, Michael S., Lazar, Alexander J., Lazar, Alexander J., Le, Xuan, Lechan, Ronald, Lee, Darlene, Lee, Jung Il, Lee, Kenneth, Lee, Sandra, Lehman, Norman L., Leinonen, Kalle, Leraas, Kristen M., Levine, Douglas A., Lewis, Lora, Ley, Timothy, Li, Jun, Li, Wei, Liang, Han, Lichtenberg, Tara M., Lin, Pei, Linehan, W. Marston, Ling, Shiyun, Lipp, Eric, Liptay, Michael J., Liu, Jia, Liu, Wenbin, Liu, Xiuping, Liu, Yuexin, Liu, Yuexin, Logothetis, Christopher, Lohavanichbutr, Pawadee, Lolla, Laxmi, Long, Georgina, Longatto-Filho, Adhemar, Looijenga, Leendert, Lu, Yiling, Luketich, James, Luna, Augustin, Lyadov, Vladimir, Ma, Deqin, Ma, Wencai, Ma, Yussanne, Madan, Rashna, Maglinte, Dennis T., Magliocca, Kelly, Maithel, Shishir, Mallery, David, Malykh, Andrei, Mandt, Randy, Manikhas, George, Mann, Graham, Mannel, Robert, Mannelli, Massimo, Mardis, Elaine R., Mariamidze, Armaz, Mariani, Odette, Marino, Mirella, Marks, Jeffrey, Marra, Marco A., Martignetti, John A., Martin, Julie, Mattei, Luca, Mayo, Michael, Mccall, Shannon, Mcgraw, Mary, Mckercher, Ginette, Mclellan, Michael D., Mclendon, Roger, Mcpherson, Christopher, Meier, Sam, Melamed, Jonathan, Meng, Shaowu, Meric-Bernstam, Funda, Merola, Roberta, Mes-Masson, Anne-Marie, Metwalli, Adam R., Meyerson, Matthew, Mieczkowski, Piotr A., Mikkelsen, Tom, Milhem, Mohammed, Miller, Christopher A., Miller, Judy, Miller, Michael, Mills, Gordon B., Mirsaidi, Cyrus, Moiseenko, Fedor, Moncrieff, Marc, Moore, Kathleen, Moore, Richard A., Moran, Cesar, Morgan, Margaret, Morris, Scott, Morrison, Carl, Morton, Donna, Mose, Lisle E., Moser, Catherine, Moxley, Katherine, Moyer, Jeffey, Mungall, Andrew J., Mungall, Karen, Mungall, Karen L., Mura, Sergiu, Mural, Richard J., Murawa, Dawid, Muto, Michael, Muzny, Donna, Myers, Jerome, Nagorney, David, Nair, Praveen, Naresh, Rashi, Naska, Theresa, Nelson, Mark, Ng, Kwok-Shing, Nguyen, Phuong, Nissan, Moriah G., Noble, Michael S., Noss, Ardene, Noushmehr, Houtan, O'Brien, Daniel, O'Neill, Brian Patrick, Ochoa, Angelica, Ojesina, Akinyemi I., Olabode, Oluwole, Olson, Jeffrey J., Omberg, Larsson, Oosterhuis, Wolter, Ostrom, Quinn T., Owonikoko, Taofeek, Pacak, Karel, Paklina, Oxana, Parfitt, Jeremy, Park, Joong-Won, Parker, Joel S., Pass, Harvey, Patel, Tushar, Paulauskis, Joseph, Pedamallu, Chandra Sekhar, Pennell, Nathan A., Penny, Robert, Perin, Alessandro, Perou, Amy H., Perou, Charles M., Petersen, Gloria, Peterson, Lisa, Peto, Myron, Peto, Myron, Phillips, Joanna, Phillips, Sarah M., Phu, Bui Duc, Piché, Alain, Pickens, Alan, Pickering, Curtis R., Pihl, Todd, Pilarski, Robert, Pinero, Edna M. Mora, Pinto, Peter A., Pirtac, Maria, Pollo, Bianca, Pool, Mark, Porten, Sima, Postier, Russel, Potapova, Olga, Powers, James, Prados, Michael, Prince, Mark, Prunello, Marcos, Que, Florencia, Quinn, Michael, Quintero-Aguilo, Mario, Rabeno, Brenda, Rader, Janet S., Rai, Karan, Ramalingam, Suresh, Ramirez, Nilsa C., Ramondetta, Lois, Rao, Arvind, Rassl, Doris M., Rathmell, W. Kimryn, Raut, Chandrajit P., Raymond, Daniel, Reis, Rui M., Reuter, Victor, Reynolds, Sheila, Reznik, Ed, Rice, David, Richards, William G., Rintoul, Robert C., Rivera, Michael, Roach, Jeffrey, Roberts, Lewis, Robertson, A. Gordon, Robertson, A. Gordon, Robinson, Bruce, Roggin, Kevin, Roman-Roman, Sergio, Rosenthal, Howard G., Rozek, Laura, Rubin, Mark A., Rustgi, Anil K., Ryan, Michael, Saad, Fred, Sadeghi, Sara, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Sankarankuty, Ajith, Santibanez, Jireh, Sastre, Xavier, Sauter, Guido, Saw, Robyn, Scapulatempo-Neto, Cristovam, Scarpace, Lisa, Schadendorf, Dirk, Schein, Jacqueline E., Schiffman, Mark, Schilero, Cathy, Schlomm, Thorsten, Schmidt, Heather K., Schmidt, Laura S., Schoenfield, Lynn, Schultz, Andre, Schultz, Nikolaus, Schumacher, Steven E., Scolyer, Richard, Secord, Angeles, Seder, Christopher W., Sekhon, Harman, Senecal, Kelly, Sepulveda, Antonia, Setdikova, Galiya, Sexton, Katherine C., Shabunin, Alexey, Shannon, Kerwin, Sharp, Alexis, Shelley, Carl Simon, Shelton, Candace, Shelton, Troy, Shen, Hui, Shen, Hui, Shen, Ronglei, Sheridan, Robert, Sherman, Mark, Sheth, Margi, Shi, Yan, Shih, Juliann, Shih, Juliann, Shimmel, Kristen, Shin, Dong M., Shinbrot, Eve, Shipman, Cassaundra, Shmulevich, Ilya, Shriver, Craig D., Sica, Gabriel, Sifri, Suzanne, Sigmund, Rita, Signoretti, Sabina, Silveira, Henrique C. S., Simko, Jeffry, Simon, Ronald, Simons, Janae V., Singer, Samuel, Singh, Bhuvanesh, Singh, Rosy, Sipahimalani, Payal, Skelly, Tara, Sloan, Andrew E., Slotta-Huspenina, Julia, Smallridge, Robert, Smith, Jennifer, Smith-McCune, Karen, Smolenski, Kathy, Smyrk, Thomas, Sofia, Heidi J., Soloway, Matthew G., Somiari, Stella, Sood, Anil, Spellman, Paul, Spillane, Andrew, Stancul, Irina, Stanton, Melissa, Staugaitis, Susan M., Steele, Ruth, Stepa, Serghei, Stern, Marc-Henri, Stoehr, Christine, Stoehr, Robert, Stoop, Hans, Stretch, Onathan, Stuart, Joshua M., Stuart, Joshua M., Su, Tao, Sumazin, Pavel, Sumer, S. Onur, Sun, Qiang, Sun, Yichao, Swanson, Patricia, Swisher, Elizabeth, Synott, Maria, Tam, Angela, Tamakawa, Raina, Tamboli, Pheroze, Tan, Donghui, Tang, Yufang, Tarnuzzer, Roy, Taubert, Helge, Tavobilov, Mikhail, Taylor, Alison M., Taylor, Barry S., Tcaciuc, Diana, Tennstedt, Pierre, Thiessen, Nina, Thomas, George, Thompson, Eric, Thompson, John, Thompson, R. Houston, Thompson, Timothy, Thorp, Richard, Thorsson, Vesteinn, Tien, Nguyen Viet, Timmers, Henri, Tirapelli, Daniela, Tischler, Arthur, Torbenson, Michael, Troncoso, Patricia, Tsai, Kenneth Y., Tsao, Anne, Tse, Kane, Tucker, Kelinda, Têtu, Bernard, Unterberg, Andreas, Urba, Walter, Valdivieso, Federico, Van Bang, Nguyen, Van Den Berg, David J., van Kessel, Kim E., Van Meir, Erwin G., Van Tine, Brian, Van Waes, Carter, Vandenberg, Scott, Veluvolu, Umadevi, Vicha, Ales, Vidal, Daniel O., Vocke, Cathy D., Voet, Doug, von Deimling, Andreas, Voronina, Olga, Wach, Sven, Wakely, Paul, Waldmann, Jens, Walker, Joan, Walter, Vonn, Wan, Yunhu, Wang, Chen, Wang, Jing, Wang, Jing, Wang, Jioajiao, Wang, Linghua, Wang, Min, Wang, Timothy, Wang, Zhining, Warnick, Ronald, Weinstein, John N., Weinstein, John N., Weisenberger, Daniel J., Wentzensen, Nicolas, Westervelt, Peter, Wheeler, David A., Wilkerson, Matthew D., Williams, Felicia, Wilmott, James, Wilson, Richard K., Wise, Lisa, Wistuba, Ignacio, Wiznerowicz, Maciej, Wolf, Gregory, Wolinsky, Yingli, Wong, Christopher K., Wong, Christopher K., Wong, Tina, Worrell, Robert, Wu, Ye, Wullich, Bernd, Xi, Liu, Yang, Hannah, Yang, Ian, Yang, Ju Dong, Yang, Liming, Yau, Christina, Yau, Christina, Yena, Peggy, Zach, Leigh Anne, Zaren, Howard, Zelinka, Tomas, Zenklusen, Jean C., Zhang, Hailei, Zhang, Hongxin, Zhang, Hongzheng, Zhang, Jiashan (Julia), Zhang, Jiexin, Zhang, Lizhi, Zhang, Wei, Zhao, Fengmei, Zhou, Jane H., Zhou, Wanding, Zmuda, Erik, Zuna, Rosemary, Zuna, Rosemary, Zwarthoff, Ellen C. +784 morecore +2 more sourcesIndependent duplications of the Golgi phosphoprotein 3 oncogene in birds
Scientific Reports, 2021 Golgi phosphoprotein 3 (GOLPH3) was the first reported oncoprotein of the Golgi apparatus. It was identified as an evolutionarily conserved protein upon its discovery about 20 years ago, but its function remains puzzling in normal and cancer cells.Juan C. Opazo, Michael W. Vandewege, Javier Gutierrez, Kattina Zavala, Luis Vargas-Chacoff, Francisco J. Morera, Gonzalo A. Mardones +6 moredoaj +1 more sourceBridging the Gap between Glycosylation and Vesicle Traffic [PDF]
, 2016 Glycosylation is recognized as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus.Abdul Rahman, Axelsson, Baas, Baker, Banfield, Bentley, Carr, Cheung, Cottam, Cottam, Dejgaard, Demircioglu, Drin, Eckert, Faid, Foulquier, Fridmann-Sirkis, Fukuda, Gawlitzek, Gilchrist, Gillingham, Grasa, Ha, Hassinen, Hennet, Hong, Hutagalung, Huybrechts, Ioffe, Jarvela, Joshi, Kelly, Kingsley, Kodera, Koreishi, Kornak, Kornfeld, Kosodo, Kranz, Kudlyk, Laufman, Laufman, Laufman, Lees, Lobingier, Lübbehusen, Maeda, Malsam, McDonald, McNew, Miller, Miller, Miserey-Lenkei, Misura, Nairn, Oka, Ong, Orci, Paesold-Burda, Papanikou, Park, Patterson, Peanne, Peng, Petrosyan, Petrosyan, Pfeffer, Pokrovskaya, Puthenveedu, Rabouille, Reynders, Rivinoja, Rymen, Rymen, Sato, Schmitz, Schnorrer, Setty, Sharpe, Shestakova, Shi, Sinka, Smits, Sohda, Sohda, Stanley, Starr, Steet, Struwe, Suvorova, Togneri, Tu, Uemura, Ungar, van Galen, Willett, Willett, Witkos, Wong, Wu, Xiang, Xu, Yamaguchi, Yamane, Ye, Yu +105 morecore +2 more sourcesGolgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway
BMC Cancer, 2018 Background Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related deaths worldwide. Despite new technologies in diagnosis and treatment, the incidence and mortality of HCC continue rising.Hongying Liu, Xieqi Wang, Bing Feng, Lipeng Tang, Weiping Li, Xirun Zheng, Ying Liu, Yan Peng, Guangjuan Zheng, Qinglian He +9 moredoaj +1 more sourceGOLPH3 Promotes Cancer Growth by Interacting With STIP1 and Regulating Telomerase Activity in Pancreatic Ductal Adenocarcinoma
Frontiers in Oncology, 2020 Overexpression of Golgi phosphoprotein 3 (GOLPH3) predicts poor prognosis and is a potential therapeutic target in pancreatic ductal adenocarcinoma (PDAC).Kebing Wang, Shuai Jiang, Anpei Huang, Ying Gao, Baogang Peng, Zhi Li, Wenbin Ma, Zhou Songyang, Shihong Zhang, Meifang He, Wen Li +10 moredoaj +1 more sourceMetformin alleviates nickel-refining fumes-induced aerobic glycolysis via AMPK/GOLPH3 pathway in vitro and in vivo
Ecotoxicology and Environmental Safety, 2022 Nickel (Ni) compounds is recognized industrial carcinogen, which could increase the risk of lung cancer in Ni refineries workers. However, the underlying carcinogenic mechanism still remains to elucidate.Tong Zhang, Yue Wang, Yangyang Chen, Ying Gao, Dan Zhang, Shuo Jin, Wenxue Yao, Lina Li, Shikuan Yang, Yonghui Wu +9 moredoaj +1 more sourceImpaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica [PDF]
, 2018 Gerodermia osteodysplastica (GO) is characterized by skin laxity and early-onset osteoporosis. GORAB, the responsible disease gene, encodes a small Golgi protein of poorly characterized function.Abo Khayal, Layal, Armling, Michael, Busse, Björn, Chan, Danny, Chan, Wing Lee, Egerer, Johannes, Hausser, Ingrid, Knaus, Petra, Kolanczyk, Mateusz, Kornak, Uwe, Lowe, Martin, Mizumoto, Shuji, Mundlos, Stefan, Ott, Claus-Eric, Paganini, Chiara, Pestke, Jan M., Rossi, Antonio, Schinke, Thorsten, Steiner, Magdalena, Sugahara, Kazuyuki, Willie, Bettina, Witkos, Tomasz, Zhang, Haikuo +22 morecore +4 more sourcesGOLPH3 Regulates EGFR in T98G Glioblastoma Cells by Modulating Its Glycosylation and Ubiquitylation [PDF]
International Journal of Molecular Sciences, 2020 Protein trafficking is altered when normal cells acquire a tumor phenotype. A key subcellular compartment in regulating protein trafficking is the Golgi apparatus, but its role in carcinogenesis is still not well defined. Golgi phosphoprotein 3 (GOLPH3), a peripheral membrane protein mostly localized at the trans-Golgi network, is overexpressed in ...Arriagada, Cecilia, Cavieres, Viviana A., Luchsinger, Charlotte, Gonzalez, Alexis E., Munoz, Vanessa C., Cancino, Jorge, Burgos, Patricia, V, Mardones, Gonzalo A. +7 moreopenaire +3 more sources
