Results 21 to 30 of about 34,844 (152)
Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. [PDF]
The Journal of cell biology, 1993 Glycosyl-phosphatidylinositol (GPI)-linked proteins are transported to the apical surface of epithelial cells where they undergo cholesterol-dependent clustering in membrane micro-invaginations, termed caveolae or plasmalemmal vesicles. However, the sorting machinery responsible for this caveolar-clustering mechanism remains unknown.
M P, Lisanti, Z L, Tang, M, Sargiacomo
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Neurobiology of Disease, 2020 Many aggregation-prone proteins linked to neurodegenerative disease are post-translationally modified during their biogenesis. In vivo pathogenesis studies have suggested that the presence of post-translational modifications can shift the aggregate ...
Julia A. Callender +9 more
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Nanoscale effects of ethanol and naltrexone on protein organization in the plasma membrane studied by photoactivated localization microscopy (PALM). [PDF]
PLoS ONE, 2014 BACKGROUND: Ethanol affects the signaling of several important neurotransmitter and neuromodulator systems in the CNS. It has been recently proposed that ethanol alters the dynamic lateral organization of proteins and lipids in the plasma membrane ...
Steven J Tobin +5 more
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The cation‐independent mannose‐6‐phosphate receptor binds to soluble GPI‐linked proteins via mannose‐6‐phosphate [PDF]
FEBS Letters, 1995 The cation‐independent mannose‐6‐phosphate/insulin‐like growth factor II receptor has been observed to bind to soluble forms of glycosyl‐phosphatidylinositol‐linked molecules, one of mammalian origin (rat Thy‐1) and two of protozoan origins. Of the two phosphate groups found on the soluble forms of the protozoan glycosyl‐phosphatidylinositol‐linked ...
Green, Paula J. +3 more
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mBio, 2012 Cell wall proteins (CWPs) mediate important cellular processes in fungi, including adhesion, invasion, biofilm formation, and flocculation. The current model of fungal cell wall organization includes a major class of CWPs covalently bound to β-1,6-glucan
Nicole M. Gilbert +3 more
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Growth factor‐induced release of a glycosyl‐phosphatidylinositol (GPI)‐linked protein from the HEp‐2 human carcinoma cell line [PDF]
FEBS Letters, 1990 The release of a GPI‐linked oncofetal protein (PLAP) from HEp‐2 cells has been studied as an indicator of endogenous PI‐specific PLC activation. A non‐hydrolysable GTP analogue, EGF and insulin all produced a dose‐dependent release of PLAP from these cells.
Roberts, Julia M. +2 more
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PredGPI: a GPI-anchor predictor
BMC Bioinformatics, 2008 Background Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-terminal residue after a proteolytic cleavage occurring at the so called ω ...
Casadio Rita +2 more
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Genome-wide prediction of the polymorphic Ser gene family in Tetrahymena thermophila based on motif analysis. [PDF]
PLoS ONE, 2014 Even though antigenic variation is employed among parasitic protozoa for host immune evasion, Tetrahymena thermophila, a free-living ciliate, can also change its surface protein antigens.
Patrath Ponsuwanna +2 more
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F1000Research, 2016 Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare disease that has been investigated for over one century and has revealed unique aspects of the pathogenesis and pathophysiology of a hemolytic anemia.
Lucio Luzzatto
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Epididymosomes: transfer of fertility-modulating proteins to the sperm surface
Asian Journal of Andrology, 2015 A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation.
Patricia A Martin-DeLeon
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