Results 31 to 40 of about 56,362 (206)

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda, Aimanianda, Al-Fattani, Albrecht, Albuquerque, Alvarez, Arroyo, Babady, Baker, Beauvais, Beauvais, Beauvais, Becker, Bonhomme, Bowen, Brown, Bruno, Bulmer, Butler, Cabib, Cabib, Cabib, Cabib, Casadevall, Casadevall, Cassone, Cassone, Castillo, Chaffin, Cheetham, Cho, Coronado, Couto, Crowe, Cushion, Cutler, Cutler, Da Silva, Dadachova, Dadachova, Dague, Dan, De Las Peñas, Del Poeta, DeMarini, Dennehy, Doering, Domer, Douglas, Douglas, Duro, Eisenhaber, Eisenman, Ene, Erwig, Fairlamb, Fernandes, Firon, Fleet, Fontaine, Frieman, Fu, Gagnon-Arsenault, García, García, Gilbert, Glasgow, Gravelat, Gresnigt, Groot, Groot, Groot, Groot, Hall, Hancock, Henry, Herrero, Hiller, Hilpert, Hohl, Hoyer, Hurtado-Guerrero, Ibrahim, Iorio, Irazoqui, Ito, Johnson, Kanetsuna, Karababa, Kaur, Kim, Klis, Klis, Klutts, Kozubowski, Kozubowski, Lamaris, Langfelder, Larsen, Latge, Latgé, Lee, Lee, Lee, Lenardon, Lenardon, Lesage, Levin, Li, Li, Li, Lipschutz, Lombard, Ma, Ma, MacCallum, Machesky, Macho, Martinez, Marty, Martín-Cuadrado, McFadden, Mentlak, Money, Money, Morelle, Morozov, Mouyna, Mouyna, Moyrand, Munro, Munro, Munro, Müller, Netea, Nett, Nobile, Norice, Nosanchuk, Nosanchuk, Odds, Oliveira-Garcia, Oliveira-Garcia, Ostrosky-Zeichner, Paolo, Paris, Park, Perlin, Piotrowski, Pitarch, Popolo, Pérez, Rachini, Rajendran, Rappleye, Rappleye, Rauceo, Reese, Reese, Reese, Reid, Reinoso-Martín, Rispail, Román, Roncero, Rowbottom, Sandini, Schorr, Schuster, Seidl, Selvaggini, Sendid, Shahinian, Sheppard, Sohn, Sorgo, Spellberg, Staab, Steinbach, Steinbach, Steinberg, Steinberg, Stynen, Sudbery, Sundstrom, Sánchez-Vallet, Thompson, Torosantucci, Treitschke, Tsai, Urban, Valdivia, Vargas-Muñiz, Veerdonk, Virag, Wagener, Walker, Walker, Walker, Walton, Weber, Wessels, Wessels, Wheeler, Wheeler, Wiederhold, Wozniak, Wösten, Xin, xSchuster, Yin, Yoneda, Zaragoza, Zarnowski, Zipfel, Zupancic   +215 more
core   +1 more source

Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]

, 1994
. Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard, Dearey, Elisabeth Ann, Korndörfer, Andrea, Müller, Günter   +3 more
core   +3 more sources

A Glycosylphosphatidylinositol Anchor Is Required for Membrane Localization but Dispensable for Cell Wall Association of Chitin Deacetylase 2 in Cryptococcus neoformans

mBio, 2012
Cell wall proteins (CWPs) mediate important cellular processes in fungi, including adhesion, invasion, biofilm formation, and flocculation. The current model of fungal cell wall organization includes a major class of CWPs covalently bound to β-1,6-glucan
Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, Jennifer K. Lodge   +3 more
doaj   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies, De Vlieger, Dorien, Rossey, Iebe, Saelens, Xavier, Schepens, Bert   +4 more
core   +2 more sources

Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria [version 1; referees: 2 approved]

F1000Research, 2016
Paroxysmal nocturnal hemoglobinuria (PNH) is a very rare disease that has been investigated for over one century and has revealed unique aspects of the pathogenesis and pathophysiology of a hemolytic anemia.
Lucio Luzzatto
doaj   +1 more source

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill, Ansari AA, Atvinder K. Rullay, Bertozzi CR, Blanch EW, Borchelt D, Caughey B, Caughey B, Caughey B, Caughey BW, Critchley P, David H. Crout, Eberl H, Ferris A, Georges C, Gill AC, Govaerts C, Haire LF, Harris DA, Hornemann S, Ian D. Sylvester, Imanpreet K. Bath, Kazlauskaite J, Kazlauskaite J, Kenyon GL, King SA, Kirby L, Klein TR, Kocienski PJ, Legname G, Matthew R. Hicks, Mui B, Nosjean O, Pan KM, Poss AJ, Safar J, Seddon AM, Shyng SL, Stahl N, Stahl N, Teresa J. T. Pinheiro, Whitesell JK, Wuthrich K, Zahn R, Zhang ZY   +44 more
core   +1 more source

Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. [PDF]

The Journal of cell biology, 1993
Glycosyl-phosphatidylinositol (GPI)-linked proteins are transported to the apical surface of epithelial cells where they undergo cholesterol-dependent clustering in membrane micro-invaginations, termed caveolae or plasmalemmal vesicles. However, the sorting machinery responsible for this caveolar-clustering mechanism remains unknown.
M P, Lisanti, Z L, Tang, M, Sargiacomo
openaire   +2 more sources

Lactoferrin efficiently counteracts the inflammation-induced changes of the iron homeostasis system in macrophages [PDF]

, 2017
Human lactoferrin (hLf), an 80-kDa multifunctional iron-binding cationic glycoprotein, is constitutively secreted by exocrine glands and by neutrophils during inflammation. hLf is recognized as a key element in the host immune defense system.
Aisen, Andrews, Baker, Barber, Cairo, Corna, Cutone, De Domenico, Donovan, Frazer, Frioni, Ganz, Ganz, Genin, Legrand, Mackenzie, Mazumder, Miller, Musci, Paesano, Paesano, Paesano, Paesano, Park, Puddu, Puddu, Recalcati, Ross, Scorneaux, Theil, Valenti, Ward   +31 more
core   +2 more sources

Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]

, 2016
In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Angiolella, Letizia, Castagnola, Massimo, Iavarone, Federica, Leone, Claudia, Marzano, Valeria, Vavala, Elisabetta, Vitali, Alberto   +6 more
core   +5 more sources

PredGPI: a GPI-anchor predictor

BMC Bioinformatics, 2008
Background Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-terminal residue after a proteolytic cleavage occurring at the so called ω ...
Casadio Rita, Martelli Pier, Pierleoni Andrea   +2 more
doaj   +1 more source