Results 51 to 60 of about 19,033 (167)

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1487-1505, May 2026.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

GPR30, Mineralocorticoid Receptors, and the Rapid Vascular Effects of Aldosterone [PDF]

Hypertension, 2011
See related article, pp 442–451 It is now generally accepted that in common with other steroid hormones aldosterone has rapid nongenomic effects, in addition to those mediated via DNA-directed, RNA-mediated protein synthesis. The currently accepted physiology of aldosterone was primarily charted by nephrologists, who understandably focused on the ...
openaire   +2 more sources

Validation data of a rabbit antiserum and affinity purified polyclonal antibody against the N-terminus of human GPR30

Data in Brief, 2016
Rabbit antiserum was generated against the N-terminus of human GPR30 followed by peptide affinity purification. In this article, the methodology used and validation data are presented.
Mohan C. Manjegowda, Paridhi Singhal Gupta, Anil M. Limaye   +2 more
doaj   +1 more source

Prunetin in a GPR30-dependent manner mitigates renal ischemia/reperfusion injury in rats via interrupting indoxyl sulfate/TLR4/TRIF, RIPK1/RIPK3/MLKL, and RIPK3/PGAM5/DRP-1 crosstalk

Saudi Pharmaceutical Journal, 2023
The potential health benefits of phytochemicals in preventing and treating diseases have gained increasing attention. Here, we proved that the methylated isoflavone prunetin possesses a reno-therapeutic effect against renal ischemia/reperfusion (I/R ...
Ahmed B. Hamed, Hanan S. El-Abhar, Dalaal M. Abdallah, Kawkab A. Ahmed, Yasmin S. Abulfadl   +4 more
doaj   +1 more source

Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging

Food Safety and Health, Volume 4, Issue 2, Page 310-326, April 2026.
This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout, Priyadarsini Sahoo, Anuprita Ray, Shuvendu Shekhar Mohapatra   +3 more
wiley   +1 more source

Estrogen/GPR30 Signaling Contributes to the Malignant Potentials of ER-Negative Cervical Adenocarcinoma via Regulation of Claudin-1 Expression

Neoplasia: An International Journal for Oncology Research, 2018
Cervical adenocarcinomas are believed to lose estrogen response on the basis of no expression of a nuclear estrogen receptor such as ERα in clinical pathology.
Taishi Akimoto, Akira Takasawa, Kumi Takasawa, Tomoyuki Aoyama, Masaki Murata, Makoto Osanai, Tsuyoshi Saito, Norimasa Sawada   +7 more
doaj   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source

G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis

Journal of Orthopaedic Translation
Background: Osteoarthritis (OA) is the most common joint disease worldwide, but its cause remains unclear. Oestrogen protects against OA, but its clinical use is limited. G protein-coupled receptor 30 (GPR30) is a receptor that binds oestrogen, and GPR30
Zhen Zhao, Shun Niu, Jun Chen, Hongtao Zhang, Lizuo Liang, Kui Xu, Chuan Dong, Chang Su, Tao Yan, Yongqiang Zhang, Hua Long, Le Yang, Minggao Zhao   +12 more
doaj   +1 more source

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Is GPR30 the Membrane Aldosterone Receptor Postulated 20 Years Ago? [PDF]

Hypertension, 2011
To the Editor: Gros et al1 describe the involvement of GPR30 in rapid actions of aldosterone. The hypothesis that a structure other than the mineralocorticoid receptor (MR) may mediate rapid actions of aldosterone was postulated many years ago. Wehling et al2 showed in 1991 that the rapid effect of aldosterone on the sodium-proton exchanger in human ...
Alexandra, Wendler, Martin, Wehling
openaire   +2 more sources