Results 201 to 210 of about 29,098 (325)

Homocysteine induces ferroptosis in cardiomyocytes by disrupting β-catenin/GPX4 pathway. [PDF]

PLoS One
Lei Y, Liu R, Xu L, Zhao Y.
europepmc   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinoma. [PDF]

Oncol Res
Zhang YU, Wang Q, Han Y, Piao J, Jin X.
europepmc   +1 more source

Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis

, 2023
Shan Liu, Hai‐Liang Zhang, Jing Li, Zhipeng Ye, Tian Du, Lichao Li, Yi-Qing Guo, Dong Yang, Zhiling Li, Jiang-Hua Cao, Bingxin Hu, Yuhong Chen, Gong‐Kan Feng, Zhiming Li, Rong Deng, Jiajia Huang, Xiaofeng Zhu   +16 more
openalex   +1 more source

Remolding Waste Liquid From the Zeolite Synthesis Process Into Wrinkled Dressings for Diabetic Wound Therapeutics With Immunomodulation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Waste liquid from natural clay‐to‐zeolite synthesis is remolded into a metal‐wrinkled dressing showing outstanding hemostatic, antibacterial, and wound‐healing effects. Chronic wounds resulting from diabetes are among the most common complications in diabetic patients.
Hanlin Yao, Xinyu You, Songqi Wu, Yunhao Wang, Di Hu, Yongsheng Ma, Jun Luo, Jie Qiu, Lihua Zhou   +8 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells. [PDF]

Eur J Med Res
Lei M, Liu B, Wan B, Feng Y, Teng Y, Xi D, Zeng G, Zong S.   +7 more
europepmc   +1 more source

Radio-Adaptive Responses of Mouse Myocardiocytes [PDF]

One of the most significant occupational hazards to an astronaut is the frequent exposure to radiation. Commonly associated with increased risk for cancer related morbidity and mortality, radiation is also known to increase the risk for cardiovascular ...
Seawright, John W., Westby, Christian M.
core   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Emerging Therapeutic Strategies Targeting GPX4-Mediated Ferroptosis in Head and Neck Cancer. [PDF]

Int J Mol Sci
Lee J, Seo Y, Roh JL.
europepmc   +1 more source