Results 61 to 70 of about 189,801 (353)

Serum Granulocyte Colony-Stimulating Factor and Alzheimer’s Disease

Dementia and Geriatric Cognitive Disorders Extra, 2012
Background: Granulocyte colony-stimulating factor (G-CSF) promotes the survival and function of neutrophils. G-CSF is also a neurotrophic factor, increasing neuroplasticity and suppressing apoptosis. Methods: We analyzed G-CSF levels in 197 patients with
Robert C. Barber, Melissa I. Edwards, Guanghua Xiao, Ryan M. Huebinger, Ramon Diaz-Arrastia, Kirk C. Wilhelmsen, James R. Hall, Sid E. O’Bryant   +7 more
doaj   +1 more source

The effect of pegbovigrastim on circulating neutrophil count in dairy cattle : a randomized controlled trial [PDF]

, 2018
Previous research in various species has shown that granulocyte-colony stimulating factor stimulates the production and release of neutrophils from bone marrow.
Bogado Pascottini, Osvaldo Américo, Carrier, J, LeBlanc, SJ, Van Schyndel, SJ   +3 more
core   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

A nitrous oxide/oxygen fixed mixture to reduce pain induced by the hypodermic injection: study protocol for a randomized, controlled trial

Trials
Background Patients with hematological malignancies received multiple hypodermic injections of recombinant human granulocyte colony-stimulating factor.
Jun-Jun Zhang, Ping Yu, Hui Dang, Cheng-Shuang Feng, Xiu-Jiang Long, Wen-Fa Huang, Lei Wang, Jie-Ling Li, Guo-Liang Tian, Jia-Quan Wen, Jun-Hui Mei, Yu-Xiang Li   +11 more
doaj   +1 more source

Renal Cell Carcinoma Producing Granulocyte Colony-stimulating Factor

Journal of the Formosan Medical Association, 2006
Severe neutrophilia caused by renal cell carcinoma secreting granulocyte colony-stimulating factor (G-CSF) is a rare manifestation of renal cancer. A 70-year-old woman presented with a 2-year history of severe anemia, severe neutrophilia and elevated ...
Yen-Chieh Wang, Stone Yang
doaj   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Role of granulocyte colony stimulating factor (G-CSF) in dengue patients with severe thrombocytopenia

Journal of the Pakistan Medical Association
Objective: To determine the effects of granulocyte colony-stimulating factor in improving platelet count in patients with dengue fever. Method: The retrospective, cross-sectional study was conducted at Northwest General Hospital and Research Centre ...
Kamran Amir Khan, Sameed Ullah Qureshi
doaj   +1 more source

Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast–Dendritic Cell Crosstalk in Atopic Dermatitis

Advanced Science, EarlyView.
Single‐cell RNA sequencing revealed that MIF signaling drives inflammatory fibroblastmyeloid cell crosstalk in atopic dermatitis. Cinobufagin, a potent PDE4D inhibitor, suppresses MIF and reduces inflammation by restoring the cAMP/PKA/CREB pathway. Genetic knockout validates PDE4D as a key driver and promising therapeutic target for atopic dermatitis ...
Shicong Li, Dihui Xu, Chenyang Zhang, Chunxiu Xiao, Meng Yu, Jiaojiao Wang, Wenyuan Wu, Xiang Lv, Dongping Yuan, Liang Zhang, Min Hong, Jing Zhou, Yang Sun, Hongyue Ma, Yuyu Zhu   +14 more
wiley   +1 more source

A Case of Squamous Cell Carcinoma of the Lung That Produced Granulocyte Colony-Stimulating Factor and Interleukin-6

Case Reports in Medicine, 2013
A 77-year-old woman visited our institution complaining of general fatigue. Chest radiography revealed masses in the upper and middle lung fields. Pathological findings for an endoscopic biopsy specimen revealed squamous cell carcinoma.
Nobuhiro Takeuchi, Kento Yamamoto, Kazuyoshi Naba   +2 more
doaj   +1 more source

Granulocyte Colony‐Stimulating Factorin Amniotic Fluid

Infectious Diseases in Obstetrics and Gynecology, 1995
Objective: The purpose of this study was to determine if granulocyte colony‐stimulating factor (G‐CSF) is normally present in amniotic fluid and then to determine if amniotic‐fluid G‐CSF levels are affected by labor and intrauterine infection.Methods: Amniotic fluid was collected from 35 patients in 4 groups: no labor, early labor, late labor, and ...
Penny Clark, B. Denise Raynor, Patrick Duff   +2 more
openaire   +3 more sources