Results 41 to 50 of about 400,493 (285)

Learning the Biochemical Basis of Axonal Guidance: Using Caenorhabditis elegans as a Model

open access: yesBiomedicines, 2023
Aim: Experimental models are a powerful aid in visualizing molecular phenomena. This work reports how the worm Caenorhabditis elegans (C. elegans) can be effectively explored for students to learn how molecular cues dramatically condition axonal guidance
Andreia Teixeira-Castro   +7 more
doaj   +1 more source

The nonuniqueness of the tangent cones at infinity of Ricci-flat manifolds

open access: yes, 2016
It is shown by Colding and Minicozzi the uniqueness of the tangent cone at infinity of Ricci-flat manifolds with Euclidean volume growth which has at least one tangent cone at infinity with a smooth cross section.
Hattori, Kota
core   +1 more source

Growth cone-growth cone interactions in cultures of rat sympathetic neurons

open access: yesDevelopmental Biology, 1989
Growth cones of sympathetic neurons from the superior cervical ganglia of neonatal rats were studied using video-microscopy to determine events following contact between growth cones and other cell surfaces, including other growth cones and neurites. A variety of behaviors were observed to occur upon contact between growth cones.
J K, Ivins, R N, Pittman
openaire   +2 more sources

Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development

open access: yeseLife, 2015
Filopodial dynamics are thought to control growth cone guidance, but the types and roles of growth cone dynamics underlying neural circuit assembly in a living brain are largely unknown.
Mehmet Neset Özel   +3 more
doaj   +1 more source

Frataxin Deficit Leads to Reduced Dynamics of Growth Cones in Dorsal Root Ganglia Neurons of Friedreich’s Ataxia YG8sR Model: A Multilinear Algebra Approach

open access: yesFrontiers in Molecular Neuroscience, 2022
Computational techniques for analyzing biological images offer a great potential to enhance our knowledge of the biological processes underlying disorders of the nervous system. Friedreich’s Ataxia (FRDA) is a rare progressive neurodegenerative inherited
Diana C. Muñoz-Lasso   +19 more
doaj   +1 more source

Influence of umbrella pine (Pinus pinea L.) stand type and tree characteristics on cone production [PDF]

open access: yes, 2016
Most umbrella pine (Pinus pinea L.) stands are managed as agroforestry systems, whose main production is fruit, due to the edible and highly nutritious kernels, and are frequently associated to natural or seeded pastures and grazing.
Afonso, Anabela   +3 more
core   +1 more source

Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

open access: yeseLife, 2018
Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces.
Kentarou Baba   +9 more
doaj   +1 more source

Roles of dual specificity tyrosine-phosphorylation-regulated kinase 2 in nervous system development and disease

open access: yesFrontiers in Neuroscience, 2022
Dual specificity tyrosine-phosphorylation-regulated kinases (DYRKs) are a group of conserved eukaryotic kinases phosphorylating tyrosine, serine, and threonine residues. The human DYRK family comprises 5 members (DYRK1A, DYRK1B, DYRK2, DYRK3, and DYRK4).
Gabriel Nicolás Santos-Durán   +1 more
doaj   +1 more source

A conic manifold perspective of elliptic operators on graphs

open access: yes, 2007
We give a simple, explicit, sufficient condition for the existence of a sector of minimal growth for second order regular singular differential operators on graphs. We specifically consider operators with a singular potential of Coulomb type and base our
Birkhoff   +14 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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