Results 41 to 50 of about 372,166 (319)
Frontiers in Neuroscience, 2022 Dual specificity tyrosine-phosphorylation-regulated kinases (DYRKs) are a group of conserved eukaryotic kinases phosphorylating tyrosine, serine, and threonine residues. The human DYRK family comprises 5 members (DYRK1A, DYRK1B, DYRK2, DYRK3, and DYRK4).
Gabriel Nicolás Santos-Durán +1 more
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Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development
eLife, 2015 Filopodial dynamics are thought to control growth cone guidance, but the types and roles of growth cone dynamics underlying neural circuit assembly in a living brain are largely unknown.
Mehmet Neset Özel +3 more
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Frontiers in Molecular Neuroscience, 2022 Computational techniques for analyzing biological images offer a great potential to enhance our knowledge of the biological processes underlying disorders of the nervous system. Friedreich’s Ataxia (FRDA) is a rare progressive neurodegenerative inherited
Diana C. Muñoz-Lasso +19 more
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The nonuniqueness of the tangent cones at infinity of Ricci-flat manifolds
, 2016 It is shown by Colding and Minicozzi the uniqueness of the tangent cone at infinity of Ricci-flat manifolds with Euclidean volume growth which has at least one tangent cone at infinity with a smooth cross section.
Hattori, Kota
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Substrate Deformation Predicts Neuronal Growth Cone Advance [PDF]
, 1977 Although pulling forces have been observed in axonal growth for several decades, their underlying mechanisms, absolute magnitudes, and exact roles are not well understood.
Athamneh, Ahmad I.M. +3 more
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Revisiting Netrin-1: One Who Guides (Axons)
Frontiers in Cellular Neuroscience, 2018 Proper patterning of the nervous system requires that developing axons find appropriate postsynaptic partners; this entails microns to meters of extension through an extracellular milieu exhibiting a wide range of mechanical and chemical properties. Thus,
Nicholas P. Boyer +2 more
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Much More Than a Scaffold: Cytoskeletal Proteins in Neurological Disorders
Cells, 2020 Recent observations related to the structure of the cytoskeleton in neurons and novel cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases are changing our view on the function of the cytoskeletal proteins in the ...
Diana C. Muñoz-Lasso +3 more
doaj +1 more source
Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and Semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons [PDF]
, 2013 Growth cone motility and morphology, which are critical for axon guidance, are controlled through intracellular events such as actin cytoskeletal reorganization and vesicular trafficking.
Goshima Yoshio +4 more
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Mechanochemical regulation of growth cone motility [PDF]
Frontiers in Cellular Neuroscience, 2015 Neuronal growth cones are exquisite sensory-motor machines capable of transducing features contacted in their local extracellular environment into guided process extension during development. Extensive research has shown that chemical ligands activate cell surface receptors on growth cones leading to intracellular signals that direct cytoskeletal ...
Patrick C Kerstein +5 more
openaire +4 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source