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Can there be growth without growth cones?
Seminars in Neuroscience, 1996Abstract In-vivo imaging of the development of complex retinotectal axon arbors indicates that arbors branches can form and extend in the absence of growth cones. A variety of imaging protocols were used to observe arbor elaboration over a range of time intervals and total observation periods.
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Pathfinding by the Growth Cone
1996The growth cone is a specialization of developing and regenerating neurons which samples the environment and is attracted or repelled by the cues it detects. Different growth cones express different surface receptors or exhibit different second messenger responses to a given cue.
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The Synapse and the Growth Cone
1991Abstract Although anatomists by the r 8gos could agree that nerve cells are separate units and interact by contacts, it left many unanswered questions. Two questions in particular aroused great interest. One was the nature of the contacts between neurons made by axons and dendrites.
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2000
'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
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'I had the good fortune to behold for the first time that fantastic ending of the growing axon. In my sections of the spinal cord of the three day chick embryo, this ending appeared as a concentration of protoplasm of conical form, endowed with amoeboid movements.
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Neuronal growth cones: An extended view
Neuroscience, 1990This commentary reviews some experiments in NG108-15 cells and their implications for the study of neurite outgrowth in primary ...
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Calcium signalling in growth cone migration
Cell Calcium, 2005Growth cones, the motile structures at the tips of advancing axons and dendrites, respond to a wide range of cues by either turning towards or away from the cue. Cytosolic calcium signals appear to mediate a large fraction of both types of response.
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