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The Growth Hormone/Prolactin Receptor Family
1993Publisher Summary This chapter provides an overview of growth hormone (GH) and prolactin receptor (PRL) family. Sequence analysis has confirmed that GH and PRL have selected regions of strong homology and, along with placental lactogen (PL) or chorionic somatotropin (CS), form a family of polypeptide hormones that appear to have arisen by the ...
P.A. KELLY +10 more
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Growth Hormone Receptor and Binding Protein
1990Publisher Summary The purification and cloning of the growth hormone (GH) receptor and the binding protein have contributed to our understanding of hormonally controlled growth in mammals. This chapter discusses the purification and cloning of growth hormone receptor and binding protein.
Spencer, Steven A. +5 more
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Molecular biology of growth hormone receptors
Trends in Endocrinology & Metabolism, 1991Growth hormone (GH), synthesized in and secreted from the anterior pituitary lobe, has multiple effects at both the cellular and the organismal levels, including promotion of body growth, stimulation of intermediary metabolism, and transcriptional regulation of specific genes.
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Growth hormone receptor antagonists.
Minerva endocrinologica, 2003Growth hormone (GH) has profound effects on vertebrate growth and cellular differentiation in diverse tissue types. Sexually dimorphic levels of circulating GH vary during development and throughout the lifespan. The synthesis and secretion of GH by the pituitary gland are precisely controlled.
D T, Kohn, J-J, Kopchick
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Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
Growth Hormone/Prolactin Receptors
1995Abstract The mature human GH receptor cloned from liver comprises 620 amino acids (aa) and is expressed with a signal sequence of 18 aa (GenBank accession number X06562). A 246-aa extracellular domain containing seven cysteine residues is followed by a transmembrane domain of 24 residues and a 350-aa intracellular domain.
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
exaly
Growth hormone-receptor antagonist pegvisomant
DMW - Deutsche Medizinische Wochenschrift, 2004B L, Herrmann, C J, Strasburger
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