Contribution of growth hormone secretagogue receptor (GHSR) signaling in the ventral tegmental area (VTA) to the regulation of social motivation in male mice. [PDF]
Transl Psychiatry, 2021 Park SB +6 more
europepmc +3 more sources
Growth hormone secretagogue receptor is important in the development of experimental colitis. [PDF]
Cell Biosci, 2015 Liu ZZ +9 more
europepmc +3 more sources
Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and promoting the phosphorylation of protein kinase B. [PDF]
Int J Mol Med, 2018 Liu Y, Liu Y, Li G, Chen Z, Gu G.
europepmc +3 more sources
Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
, 2013 The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +3 more
core +10 more sources
Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition. [PDF]
Psychopharmacology (Berl), 2015 Engel JA +4 more
europepmc +3 more sources
Diversification and coevolution of the ghrelin/growth hormone secretagogue receptor system in vertebrates. [PDF]
Ecol Evol, 2016 Tine M +4 more
europepmc +3 more sources
The ups and downs of growth hormone secretagogue receptor signaling [PDF]
The FEBS Journal, 2021 The growth hormone secretagogue receptor (GHSR) has emerged as one of the most fascinating molecules from the perspective of neuroendocrine control. GHSR is mainly expressed in the pituitary and the brain, and plays key roles regulating not only growth hormone secretion but also food intake, adiposity, body weight, glucose homeostasis and other complex
María P. Cornejo +5 more
openaire +3 more sources
Growth hormone secretagogues: history, mechanism of action, and clinical development
JCSM Rapid Communications, 2020 Growth hormone secretagogues (GHSs) are a generic term to describe compounds that increase growth hormone (GH) release. GHSs include agonists of the growth hormone secretagogue receptor (GHS‐R), whose natural ligand is ghrelin, and agonists of the growth
Junichi Ishida +5 more
doaj +1 more source
Biological, Physiological, and Pharmacological Aspects of Ghrelin
Journal of Pharmacological Sciences, 2006 .: Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor, functions as a somatotrophic and orexigenic signal from the stomach.
Hiroshi Hosoda +2 more
doaj +1 more source
The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond
IBRO Neuroscience Reports, 2022 Ghrelin is a stomach-derived peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) and displays a plethora of neuroendocrine, metabolic, autonomic and behavioral actions.
Mario Perelló +5 more
doaj +1 more source