Results 31 to 40 of about 9,099 (167)

Monitoring of cytogenetic effects in tick-borne encephalitis patients with type 2 diabetes mellitus, depending on polymorphism of glutathione-S-transferase genes

Сахарный диабет, 2019
BACKGROUND: Tick-borne encephalitis (TBE) is an acute viral disease with activation of oxidative stress and increasing in cytogenetic instability. Clinical symptoms of infectious diseases usually more severe in patients with type 2 diabetes mellitus (DM2)
Nikolay N. Ilyinskikh, Marina S. Kostromeeva, Ekaterina N. Ilyinskikh   +2 more
doaj   +1 more source

Association of Genetic Polymorphisms in GSTP1, GSTM1, and GSTT1 Genes with Vesicoureteral Reflux Susceptibility in the Children of Southeast Iran

Iranian Journal of Public Health, 2020
Background: Vesicoureteral reflux (VUR) disease is the most common type of urinary tract anomalies in children. Genetic risk factors may be associated with the etiology of VUR.  The role of the Glutathione S‑transferases (GSTs) as multifunctional enzymes
Sima SHAHROKHZADEH, Azam SOLEIMANI, Dor-Mohammad KORDI-TAMANDANI, Mohammad Hossein SANGTARASH, Omid NEJATI, Mohsen TAHERI   +5 more
doaj   +1 more source

Cumulative meta-analysis of the association between GSTT1/GSTM1-GSTT1 genetic polymorphisms and lung cancer susceptibility.

, 2014
(a) publication time cumulative meta-analysis of GSTT1 variants and lung cancer risk; (b) sample size cumulative meta-analysis of GSTT1 variants and lung cancer risk; (c) publication time cumulative meta-analysis of GSTM1-GSTT1 variants and lung cancer ...
Baobo Zou (380154), Jianmin Jiang (488872), Xia Yue (600754), Guochuan Mao (545531), Kui Liu (247249), Ting Ma (499742), Jian Chen (15340), Xialu Lin (380151), Huiqin Wang (600755), Jinshun Zhao (80435), Liyuan Han (600753), Guixiu Jin (600756), Lu Zhang (50563), Qi Zhou (7408)   +13 more
core   +1 more source

Cytogenetic effects of tick-borne encephalitis in residents of the north of Western Siberia with alimentary-constitutional obesity depending on the polymorphism of the genes of glutathione-S-transferase

Ожирение и метаболизм, 2017
Backgraund. Tick-borne encephalitis (TBE), one of the large-scale public health problems of the Siberian region, can cause significant cytogenetic damage in humans by stimulating oxidative stress. Active functioning of the detoxification system including
Ekaterina N. Ilyinskikh, Nicolai Nicolaevich Ilyinskikh   +1 more
doaj   +1 more source

Association between copy number of the GSTM1 and GSTT1 genes and risk of prostate cancer.

, 2014
aUnconditional logistic regression adjusted for age and education for GSTM1; for age and family history of prostate cancer for GSTT1; for age and PSA screening history for the sum of GSTM1 and GSTT1 alleles.bGSTM10 and GSTT10;cGSTM10 and GSTT11 or GSTM11
Luc Multigner (421573), Marc Romana (287952), Cédric Broquère (626905), Séverine Ferdinand (62784), Pascal Blanchet (421572), Laurent Brureau (626906), Elise Emeville (421568)   +6 more
core   +1 more source

Glutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related Molecular Markers for Type 2 Diabetes Mellitus

Diabetes, Metabolic Syndrome and Obesity, 2021
Amani MT Gusti,1,2 Safaa Y Qusti,1 Suhad M Bahijri,3,4 Eman A Toraih,5,6 Samia Bokhari,7 Sami M Attallah,8,9 Abdulwahab Alzahrani,10 Wafaa MA Alshehri,11 Hawazin Alotaibi,12 Manal S Fawzy13,14 1Department of Biochemistry, Faculty of Science, King ...
Gusti AMT, Qusti SY, Bahijri SM, Toraih EA, Bokhari S, Attallah SM, Alzahrani A, Alshehri WMA, Alotaibi H, Fawzy MS   +9 more
doaj  

Detection of glutathione S-transferases M1, T1 gene deletions among cancer patients in Mongolia

Proceedings of the Mongolian Academy of Sciences, 2020
Various types of toxic xenobiotic and electrophilic compounds, which were formed from the glutathione S-transferases cell metabolism and the oxidation stress, are the group enzymes with detoxification roles that are involved in the metabolism phase II ...
Temuujin Janchiv, Enkhgerel Dorj, Ochirkhuyag Baldorj, Khulan Janchiv   +3 more
doaj   +1 more source

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease (ESRD) in Colombian Patients

Environmental Toxicology, EarlyView.
ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez, Juliana Lago, Carlos Trillos, Marcela Varona, Leonardo Briceño, Ruth Marien Palma, Sonia M. Díaz, Gilma Hernández, Eliana M. Téllez, Juan Sebastián Aguilar, Daniela Castellanos, Xavier Martínez, Estefanía Zapata, Alix Rocio Barrios, Ignacio Villanueva, Michael R. Fonseca, Helena Groot   +16 more
wiley   +1 more source

GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

, 2015
The glutathione S-transferase (GST) family consists of phase II detoxification enzymes that catalyze the conjugation of toxic substances, such as chemotherapeutic agents, to glutathione.
Rodrigues, FFO, Aoki, T, Santos, RE, Oliveira, AL, Longui, CA, Rocha, MN, Melo, MB   +6 more
core   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

The FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson, Kai‐Christian Sonntag, Thao Do Vy Le, Kaitlin Shannon, Chao Wang, Fei Du, Xi Chen, Donna McPhie, Dost Ongur, Bruce Cohen, Virginie‐Anne Chouinard   +10 more
wiley   +1 more source