Results 201 to 210 of about 81,307 (285)

Functions of J‐domain proteins in mitochondrial protein biogenesis

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Mitochondrial biogenesis and functions depend on the import and assembly of more than 1000 proteins that are made as precursors on cytosolic ribosomes. The majority of these precursor proteins are transported from the ribosome to the translocase of the outer membrane (TOM complex), which constitutes the main entry site for mitochondrial ...
Vitasta Tiku, Georg Bossenz, Janine Kirstein, Thomas Becker   +3 more
wiley   +1 more source

Targeting KRAS G12D: Advances in Inhibitor Design. [PDF]

Thorac Cancer
Shi K, Li A.
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Roles of cytoskeleton in metastasis: from its mechanism to therapeutic strategies. [PDF]

Exp Mol Med
Lim S, Woo S, Lee KW, Kim KD.
europepmc   +1 more source

Dapansutrile preserves pancreatic beta‐cell function by regulating insulin vesicle membrane fusion and mitochondrial homeostasis

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3054-3069, April 2026.
Abstract Aims/Hypothesis Pancreatic beta‐cell dysfunction is pivotal in diabetes pathogenesis, with the NOD‐like receptor protein 3 (NLRP3) inflammasome playing a crucial role. Dapansutrile (DAPA), a novel NLRP3 inhibitor, demonstrates promise in diabetes management.
Ying Wu, Hongxing Fu, Min Zhu, Yuanfa Yao, Luhong Jin, Xihua Lin, Jiaqiang Zhou   +6 more
wiley   +1 more source

ARAP1 fine-tunes F-actin polymerization level in lymphocytes through RhoA inhibition. [PDF]

Front Immunol
Ueda Y, Kondo N, Kamioka Y, Kinashi T.
europepmc   +1 more source

Fruit respiration: putting alternative pathways into perspective

New Phytologist, Volume 250, Issue 1, Page 54-73, April 2026.
Summary Over the past century, research has significantly advanced our understanding of fruit respiration, from (eco)physiological processes to molecular mechanisms. This review focuses on the functional relevance and regulatory roles of mitochondrial alternative respiratory pathways (ARPs) during fruit growth and ripening.
Ariadna Iglesias‐Sanchez, Sergio García‐Carbonell, Alisdair R. Fernie, Marta Pujol, Igor Florez‐Sarasa   +4 more
wiley   +1 more source

Case Report: A novel CIITA mutation causing MHC class II deficiency: first reported case in Morocco. [PDF]

Front Immunol
Kattra AB, Ailal F, Benhsaien I, Fahi M, Drissi Bourhanbour A, Elamine A, Aadam Z, Errami A, Bousfiha AA, El Bakkouri J.   +9 more
europepmc   +1 more source