Results 211 to 220 of about 153,070 (268)

Overexpression of developmentally regulated GTP-binding protein-2 increases bone loss

American Journal of Physiology-Endocrinology and Metabolism, 2013
The developmentally regulated GTP-binding protein-2 (DRG2) is a novel subclass of GTP-binding proteins. Many functional characteristics of osteoclasts (OC) are associated with small GTPases. We hypothesized that DRG2 affects bone mass via modulating OC activity. Using DRG2 transgenic mice, we investigated the role of DRG2 in bone remodeling.
Ke, Ke, Ok-Joo, Sul, Woon-Ki, Kim, Mi-Hyun, Lee, Myung-Seok, Ko, Jae-Hee, Suh, Hyun-Ju, Kim, Shin-Yoon, Kim, Jeong-Woo, Park, Hye-Seon, Choi   +9 more
openaire   +2 more sources

The Regulation of GTP-Binding Proteins during Fertilization and Zygote Differentiation in Dictyostelium discoideum

Experimental Cell Research, 1993
The development changes in GTP-binding proteins and the regulation of their appearance by calcium ions were investigated during early sexual development in Dictyostelium discoideum. GTP gamma S strongly inhibited gamete cell fusion, while GDP beta S slightly augmented it, suggesting that G-proteins have a critical role in cell fusion.
D D, Browning, M B, Poludnikiewicz, G A, Proteau, D H, O'Day   +3 more
openaire   +2 more sources

Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins

Biochemistry and Cell Biology, 2004
The function of G protein-coupled receptors is regulated by a broad variety of membrane-bound and intracellular proteins. These act in concert to activate signaling pathways that will lead to the desensitization of activated receptors and, for most receptor types, their trafficking to intracellular compartments.
openaire   +2 more sources

Rab3 Small GTP—Binding Proteins: Regulation by Calcium/Calmodulin

2003
Rab proteins, forming a subfamily of 52 predominantly membrane-bound, low molecular weight GTP-binding proteins (G-proteins) of the Ras superfamily, are involved in vesicle traffic between intracellular organelles, endocytosis and exocytosis, and may be regulated by calcium (Ca2 +) and/or calmodulin (CaM).
Ranjinder S. Sidhu, Richard R. Clough, Rajinder P. Bhullar   +2 more
openaire   +1 more source

Rab32 regulates Golgi structure and cell migration through Protein Kinase A–mediated phosphorylation of Optineurin

Proceedings of the National Academy of Sciences of the United States of America
Significance Golgi assembly and dynamics during cell migration are tightly controlled by signaling and cytoskeletal regulators, resulting in polarized Golgi distribution that supports directional migration.
Katherine M. Johnson, Maxwell G Marley, Kristina Drizyte-Miller, Jing Chen, H. Cao, Nourhan Mostafa, Micah B. Schott, M. McNiven, G. Razidlo   +8 more
semanticscholar   +1 more source

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis

Nature, 1991
G. F. V. Mollard, T. Südhof, R. Jahn
semanticscholar   +1 more source

Isolation and characterization of Ras-related GTP-binding protein (Ran) from Lepidium latifolium L. reveals its potential role in regulating abiotic stress tolerance

Acta Physiologiae Plantarum, 2014
V. B. Sinha, A. Grover, M. Aslam, V. Pande, Z. Ahmed   +4 more
semanticscholar   +1 more source

Study of Rab6, a Ras‐like GTP‐binding Protein Associated with the Golgi Complex

Annals of the New York Academy of Sciences, 1994
B. Goud, Chunzhi Yang, M. Roa, Olivier Martinez, V. Slepnev   +4 more
semanticscholar   +2 more sources

Activation of a small GTP-binding protein by nucleoside diphosphate kinase.

Science, 1991
P. Randazzo, J. Northup, R. A. Kahn
semanticscholar   +1 more source

The GTP-binding protein, Go, regulates neuronal calcium channels.

Nature, 1987
In neuronal cells, opioid peptides and opiates inhibit neurotransmitter release, which is a calcium-dependent process. They also inhibit adenylyl cyclase, presumably via the membrane signal-transducing component, Gi, a guanine nucleotide-binding protein (G-protein). No causal relationship between these two events has yet been demonstrated.
J, Hescheler, W, Rosenthal, W, Trautwein, G, Schultz   +3 more
openaire   +1 more source