Results 211 to 220 of about 80,664 (305)

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Rho-GTPases subfamily: cellular defectors orchestrating viral infection. [PDF]

Cell Mol Biol Lett
Zhang B, Li S, Ding J, Guo J, Ma Z, Duan H.   +5 more
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

The role of small GTPases in Alzheimer's disease tau pathologies. [PDF]

Front Cell Neurosci
Hoegy P, Chen YH, Lu Q.
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Divergent Functions of Rap1A and Rap1B in Endothelial Biology and Disease. [PDF]

Int J Mol Sci
Kosuru R, Chrzanowska M.
europepmc   +1 more source

The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance

Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.
Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis, Vishwanath V. Prabhu, Bruce D. Carter   +2 more
wiley   +1 more source

A Pleiotropic and Functionally Divergent <i>RAC3</i> Variant Disrupts Neurodevelopment and Impacts Organogenesis. [PDF]

Cells
Sugawara R, Scala M, Cabet S, Abel C, Januel L, Lesca G, Guibaud L, Le Breton F, Ueda H, Tabata H, Ito H, Nagata KI.   +11 more
europepmc   +1 more source

Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14. [PDF]

J Biol Chem
Agogo-Mawuli PS, Sadiya I, Abramyan TM, Bosch DE, Emmitte KA, Colón-Pérez LM, Kosloff M, Siderovski DP.   +7 more
europepmc   +1 more source

Mixed Messages: Dynamic and Compositional Heterogeneity of Nuclear Messenger Ribonucleoprotein (mRNP) Complexes

WIREs RNA, Volume 16, Issue 6, November/December 2025.
RNA‐protein (RNP) complexes formed by a network of RNA–RNA, RNA–protein, and protein–protein interactions are central to gene expression. mRNP compositional heterogeneity underlies precise regulation (e.g., export, storage, translation, and decay), enabling cells to adapt to changing conditions, with changes in composition further linked to stress ...
Theresa Wechsler, Ryuta Asada, Ben Montpetit   +2 more
wiley   +1 more source