Results 41 to 50 of about 322,041 (407)
Protein & Cell, 2011 Small GTPases are key molecular switches that bind and hydrolyze GTP in diverse membrane- and cytoskeleton-related cellular processes. Recently, mounting evidences have highlighted the role of various small GTPases, including the members in Arf/Arl, Rab, and Ran subfamilies, in cilia formation and function.
Yujie Li, Jinghua Hu
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Plant Protection Science, 2002 Small G-proteins (RAC and RHO) are known to be involved in regulation of superoxide (O2*-) production and the assembly of actin fibres. These processes are known to be crucial for accessibility and inaccessibility of barley cells to the biotrophic fungus
H. Schultheiss +3 more
doaj +1 more source
Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch [PDF]
, 2017 [FeFe]-hydrogenases catalyse the reduction of protons to hydrogen at a complex 2Fe[4Fe4S] center called H-cluster. The assembly of this active site is a multistep process involving three proteins, HydE, HydF and HydG.
Acquasaliente, Laura +8 more
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Arf GTPase interplay with Rho GTPases in regulation of the actin cytoskeleton [PDF]
Small GTPases, 2017 The Arf and Rho subfamilies of small GTPases are nucleotide-dependent molecular switches that act as master regulators of vesicular trafficking and the actin cytoskeleton organization. Small GTPases control cell processes with high fidelity by acting through distinct repertoires of binding partners called effectors.
Singh, V. +4 more
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Small GTPases in platelet membrane trafficking
Platelets, 2019 Our understanding of fundamental biological processes within platelets is continually evolving. A critical feature of platelet biology relates to the intricate uptake, packaging and release of bioactive cargo from storage vesicles, essential in mediating
Tony G. Walsh +3 more
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DNM1 encephalopathy: A new disease of vesicle fission. [PDF]
, 2017 ObjectiveTo evaluate the phenotypic spectrum caused by mutations in dynamin 1 (DNM1), encoding the presynaptic protein DNM1, and to investigate possible genotype-phenotype correlations and predicted functional consequences based on structural modeling ...
Campbell, Colleen A +38 more
core +2 more sources
Rho GTPases and spermatogenesis
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2003 Rho GTPases, such as Rho, Rac and Cdc42, are known to regulate many cellular processes including cell movement and cell adhesion. While the cellular events of germ cell movement are crucial to spermatogenesis since developing germ cells must migrate progressively from the basal to the adluminal compartment but remain attached to the seminiferous ...
Lee, WM, Lui, WY, Cheng, CY
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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]
, 2013 Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts +79 more
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Multiple Roles of the Small GTPase Rab7
Cells, 2016 Rab7 is a small GTPase that belongs to the Rab family and controls transport to late endocytic compartments such as late endosomes and lysosomes. The mechanism of action of Rab7 in the late endocytic pathway has been extensively studied.
Flora Guerra, C. Bucci
semanticscholar +1 more source
Dynamin-catalyzed membrane fission requires coordinated GTP hydrolysis. [PDF]
PLoS ONE, 2013 Dynamin is the most-studied membrane fission machinery and has served as a paradigm for studies of other fission GTPases; however, several critical questions regarding its function remain unresolved.
Ya-Wen Liu +2 more
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