Results 131 to 140 of about 46,713 (191)

Studying the Role of Myenteric Amyloidosis in Gastrointestinal Dysmotility and Enteric Neural Dysfunction Using APP/PS1 Mice—Is It an Adequate Animal Model?

Neurogastroenterology &Motility, EarlyView.
Amyloidosis in the central and enteric nervous system contributes to cognitive deficits and gastrointestinal dysmotility—the constipation in Alzheimer's disease (AD). APP/PS1 mice, a transgenic mouse model of amyloidosis, recapitulated the amyloidosis in the central nervous system; they were unsustainable in recapitulating the amyloidosis in the ...
Roxanne Fernandes, Marlene Masino, Emma Flood, Theresa A. Lansdell, Nikitha Srikrishna, Ryan Mui, Anne M. Dorrance, James J. Galligan, Hui Xu   +8 more
wiley   +1 more source

Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for G6PD deficiency

Tropical Medicine &International Health, Volume 30, Issue 5, Page 437-457, May 2025.
Abstract Accurate diagnosis of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is crucial for relapse malaria treatment using 8‐aminoquinolines (primaquine and tafenoquine), which can trigger haemolytic anaemia in G6PD‐deficient individuals. This is particularly important in regions where the prevalence of G6PD deficiency exceeds 3%–5%, including ...
Usa Boonyuen, Beatriz Aira C. Jacob, Kamonwan Chamchoy, Natnicha Pengsuk, Sirinyatorn Talukam, Chanya Petcharat, Emily R. Adams, Thomas Edwards, Kobporn Boonnak, Syazwani Itri Amran, Nurriza Ab Latif, Naveen Eugene Louis   +11 more
wiley   +1 more source

THE ACIDOSIS OF GUANIDINE INTOXICATION 1 [PDF]

Journal of Clinical Investigation, 1934
A. S. Minot, Katharine Dodd, J. M. Saunders   +2 more
openaire   +3 more sources

Chronic intermittent hypoxia‐mediated cognitive dysfunction in ovariectomized rats

Experimental Physiology, EarlyView.
Abstract Obstructive sleep apnoea (OSA) is a prevalent cardiorespiratory disorder associated with significant neurocognitive consequences. Despite the higher prevalence of OSA in men, there is a strong association between OSA and Alzheimer's disease (AD), which disproportionately affects women.
Emily C. Cheung, Joan B. Escobar, Bridget R. Alber, Caitlin Ribeiro, Ishan Abdullah, Grant Kowalik, Jeannette Rodriguez, Grey Harral, Makeda Melkie, Aman Gill, John T. Ketzenberger, John Bethea, Vsevolod Y Polotsky, Vivek Jain, Kathryn Schunke, Matthew W. Kay, David Mendelowitz   +16 more
wiley   +1 more source

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

The Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai, Xijin Xu, Xia Huo, Joost H. N. Schuitemaker, Marijke M. Faas   +4 more
wiley   +1 more source

A method for the isolation of guanidine [PDF]

Biochemical Journal, 1932
openaire   +3 more sources

LC‐IRMS Persulfate Oxidation: Case Study on Neonicotinoid‐Related Structures

Rapid Communications in Mass Spectrometry, Volume 39, Issue 16, 30 August 2025.
ABSTRACT Rationale Liquid chromatography‐isotope ratio mass spectrometry (LC‐IRMS) is used to analyze stable carbon isotope ratios of polar nonvolatile compounds. However, challenges with the persulfate‐based oxidation interface have been reported, particularly for molecules with recalcitrant structures like those found in neonicotinoids.
Felix Niemann, Annika Gruhlke, Maik A. Jochmann, Torsten C. Schmidt   +3 more
wiley   +1 more source

THE PREPARATION OF GUANIDINE [PDF]

Journal of Biological Chemistry, 1917
openaire   +1 more source

Uraemic syndrome following acute renal failure in horses

Equine Veterinary Education, Volume 37, Issue 5, Page 235-240, May 2025.
G. van Galen
wiley   +1 more source

Silylative Kinetic Resolution of Acyclic Secondary Benzylic Alcohols Catalyzed by Chiral Guanidine Having Axial Chirality Containing a Methoxy Group

Chinese Journal of Chemistry, Volume 43, Issue 13, Page 1553-1559, 1 July 2025.
An efficient silylative kinetic resolution of acyclic secondary benzylic alcohols was achieved using chlorosilanes and new axially chiral guanidine catalysts bearing a methoxy group. Comprehensive Summary New chiral guanidine catalysts having axial chirality containing a methoxy group were synthesized. Subsequently, their catalytic ability was examined
Yuki Homma, Takahisa Ikeue, Kenya Nakata
wiley   +1 more source