Results 111 to 120 of about 15,901 (303)

In silico and in vitro approaches to develop Dimethylarginine dimethylaminohydrolase-1 inhibitors [PDF]

open access: yes, 2017
Introduction: Dimethylarginine dimethylaminohydrolases (DDAH) metabolise the endogenous nitric oxide synthase (NOS) inhibitors: asymmetric dimethylarginine (ADMA) and monomethylarginine1.
Rossiter, S.   +5 more
core  

Bio‐Inspired, Zwitterionic Copolymers with Amphiphilic Character

open access: yesMacromolecular Rapid Communications, EarlyView.
Zwitterionic copolymers based on arginine‐derived monomers are produced by xanthate‐supported photo‐iniferter reversible‐addition‐fragmentation chain‐transfer polymerization. Experiments in relevant conditions show that the designed (co)polymers hardly interact with biologically relevant proteins and enzymes such as bovine serum albumine (BSA), fetal ...
Theresa M. Lutz   +4 more
wiley   +1 more source

Bioinspired, Guanidinium, and Indole Modified Poly(glycidyl ether)s as Highly Efficient Vectors for Polyplex‐Mediated Gene Delivery

open access: yesMacromolecular Rapid Communications, EarlyView.
Guanidinium‐ and indole‐functionalized poly(glycidyl ether)s were developed as non‐viral gene delivery vectors with tunable hydrophilic–hydrophobic balance. All polymers formed stable DNA polyplexes, while moderate indole content yielded the highest transfection efficiency at low N/P ratios.
Markus Kötzsche   +8 more
wiley   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

open access: yesPest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus   +13 more
wiley   +1 more source

Design and Analysis of POM‐Guanidine Compounds: Achieving Ultra‐High Single‐Crystal Proton Conduction [PDF]

open access: bronze, 2023
Meng‐Meng Wang   +9 more
openalex   +1 more source

Interfacial Dipole Engineering With Taurine‐Modified SnO2 Electron Transport Layer for Efficient and Stable Perovskite Solar Cells

open access: yesRare Metals, EarlyView.
ABSTRACT Organic‐inorganic metal halide perovskite solar cells (PSCs) are promising for photovoltaics due to their excellent optoelectronic properties. However, achieving high efficiency and stability remains challenging, mainly due to defects and energy losses at the electron transport layer (ETL)/perovskite interface.
Jiahui Jin   +8 more
wiley   +1 more source

An Ultrasmall Strontium‐Loaded Polydopamine Nanoformulation for Near‐Infrared‐Enhanced Periodontitis Therapy via Photodynamic Gas‐Promoted Antibacterial and Bone Repair

open access: yesRare Metals, EarlyView.
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang   +14 more
wiley   +1 more source

2-Benzyl-6-carboxy-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidin-1-ium 2,2,2-trifluoroacetate

open access: yesMolbank
Cyclic guanidines are valuable scaffolds for the design of compounds acting on GABAergic neurotransmission, owing to their ability to mimic the amino functionality of GABA as bioisosteres.
Francesco Bavo   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy