Results 21 to 30 of about 15,901 (303)

New N-Benzenesulfonylguanidine Derivatives and Their Selective Growth Inhibition of Human Breast Cancer Cell Line MCF-7 and Colon Carcinoma HCT-116

Medical Sciences Forum, 2022
Our previous research proved that benzenesulfonylguanidine derivatives display significant cytotoxic activity against human cancer cells. Here, we describe new 1-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)guanidines with cytotoxic activity against HCT-
Aneta Pogorzelska, Jarosław Sławiński, Anna Kawiak   +2 more
doaj   +1 more source

Mechanochemical synthesis of thioureas, ureas and guanidines

Beilstein Journal of Organic Chemistry, 2017
In this review, the recent progress in the synthesis of ureas, thioureas and guanidines by solid-state mechanochemical ball milling is highlighted. While the literature is abundant on their preparation in conventional solution environment, it was not ...
Vjekoslav Štrukil
doaj   +1 more source

Synthesis and Activity of Biomimetic Biofilm Disruptors [PDF]

, 2013
Biofilms are often associated with human bacterial infections, and the natural tolerance of biofilms to antibiotics challenges treatment. Compounds with antibiofilm activity could become useful adjuncts to antibiotic therapy.
Böttcher, Thomas, Clardy, Jon C., Kolodkin-Gal, Ilana, Kolter, Roberto Guillermo, Losick, Richard M.   +4 more
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Interatomic Distances in Covalent Molecules and Resonance between Two or More Lewis Electronic Structures [PDF]

, 1932
In a paper to be published in the Zeitschrift für Kristallographie, Professor M. L. Huggins and I have formulated tables of radii for use in crystals containing electron-pair bonds. With the aid of these tables, we have also constructed a table of radii (
Pauling, Linus
core   +2 more sources

One-pot synthesis of dihydropyrimidines via eco-friendly phosphorus derivatives catalysis

Journal of Saudi Chemical Society, 2022
A straightforward, cost effective and eco-friendly protocol for the Biginelli reaction relying on the use of readily available hypophosphorous acid is presented.
Zakaria Moutaoukil, Cyril Ronco, Rachid Benhida   +2 more
doaj   +1 more source

Structural and mechanistic insights into s-block bimetallic catalysis : sodium magnesiate-catalyzed guanylation of amines [PDF]

, 2016
To advance the catalytic applications of s-block mixed-metal complexes, sodium magnesiate [NaMg(CH2SiMe3)3] (1) is reported as an efficient precatalyst for the guanylation of a variety of anilines and secondary amines with carbodiimides.
Alonso-Moreno, Alonso-Moreno, Andrikopoulos, Anker, Armstrong, Avila, Bailey, Baillie, Baillie, Baishya, Barker, Barr, Barrett, Berlinck, Blair, Boudet, Brinkmann, Buchdunger, Castagnolo, Clegg, Coles, Coles, Coles, Conway, Crimmin, Du, Dunne, Edelmann, Edelmann, Edelmann, Edelmann, Edelmann, Ekelund, Elorriaga, Elorriaga, Espenson, Fleming, Fleming, Forbes, Francos, Fu, Giesbrecht, Gribkov, Grirrane, Han, Harder, Harrison-Marchand, Hernán-Gómez, Hevia, Hevia, Hill, Intemann, Intemann, Ishikawa, Ishikawa, Ishikawa, Jones, Junk, Klatt, Klett, Kloetzing, Kondo, Krasovskiy, Lachs, Leow, Li, Liptrot, Liu, Liu, Loesberg, Martinez-Martinez, Martínez-Martínez, Mongin, Moxey, Mukherjee, Mulvey, Nash, Neufeld, Ong, Ong, Penafield, Piers, Romero-Fernández, Rowley, Ryu, Scheinfeld, Selig, Sheldrick, Shi, Srinivas, Taylor, Thomas, Thomasa, Tilly, Tin, Tin, Toth, Trifonov, Troncone, Vidal, von Itzstein, Weetman, Wunderlich, Xu, Xu, Zhang, Zhang, Zhang, Zhou, Zhu   +109 more
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Readily Available Chiral Benzimidazoles-Derived Guanidines as Organocatalysts in the Asymmetric α-Amination of 1,3-Dicarbonyl Compounds

Molecules, 2017
The synthesis and the evaluation as organocatalysts of new chiral guanidines derived from benzimidazoles in the enantioselective α-amination of 1,3-dicarbonyl compounds using di-t-butylazodicarboxylate as aminating agent is herein disclosed.
Llorenç Benavent, Francesco Puccetti, Alejandro Baeza, Melania Gómez-Martínez   +3 more
doaj   +1 more source

Norbornane-based antibacterial agents: Benzyl and benzoyl substituted guanidines

European Journal of Medicinal Chemistry Reports, 2022
There is a pressing need to develop new antibiotics to replace those rendered ineffective as a result of widespread antimicrobial resistance. Naturally occurring cationic antimicrobial peptides (CAMPs) exhibit broad-spectrum antibacterial activity and ...
Gareth E. Boer, Shane M. Hickey, Alysha G. Elliott, Frederick M. Pfeffer   +3 more
doaj   +1 more source

Organocatalytic Enantioselective Henry Reactions [PDF]

, 2011
This is an open access article distributed under the Creative Commons Attribution License.A large number of interesting organocatalytic enantioselective protocols have been explored and successfully applied in the last decade.
Herrera, Raquel P., Marqués-López, Eugenia, Álvarez-Casao, Yolanda   +2 more
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Identification of Bis-Cyclic Guanidines as Antiplasmodial Compounds from Positional Scanning Mixture-Based Libraries

Molecules, 2019
The screening of more than 30 million compounds derived from 81 small molecule libraries built on 81 distinct scaffolds identified pyrrolidine bis-cyclic guanidine library (TPI-1955) to be one of the most active and selective antiplasmodial libraries ...
David L. Perry, Bracken F. Roberts, Ginamarie Debevec, Heather A. Michaels, Debopam Chakrabarti, Adel Nefzi   +5 more
doaj   +1 more source