Results 41 to 50 of about 7,968 (196)

Temperature dependence of the hydrogen bond network in Trimethylamine N-oxide and guanidine hydrochloride - water solutions [PDF]

open access: yes, 2017
We present an X-ray Compton scattering study on aqueous Trimethylamine N-oxide (TMAO) and guanidine hydrochloride solutions (GdnHCl) as a function of temperature. Independent from the concentration of the solvent, Compton profiles almost resemble results for liquid water as a function of temperature.
arxiv   +1 more source

Enantioselective Michael addition of isobutyraldehyde to nitroalkenes organocatalyzed by chiral primary amine-guanidines [PDF]

open access: yes, 2014
Primary amine-guanidines derived from trans-cyclohexane-1,2-diamines are used as organocatalysts for the enantioselective conjugate addition of isobutyraldehyde to arylated and heteroarylated nitroalkenes.
Chinchilla, Rafael   +4 more
core   +2 more sources

Readily Available Chiral Benzimidazoles-Derived Guanidines as Organocatalysts in the Asymmetric α-Amination of 1,3-Dicarbonyl Compounds

open access: yesMolecules, 2017
The synthesis and the evaluation as organocatalysts of new chiral guanidines derived from benzimidazoles in the enantioselective α-amination of 1,3-dicarbonyl compounds using di-t-butylazodicarboxylate as aminating agent is herein disclosed.
Llorenç Benavent   +3 more
doaj   +1 more source

Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria

open access: yesAntibiotics, 2022
Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers ...
Danzel Marie Ramirez   +4 more
doaj   +1 more source

Chiral Guanidines

open access: yesJournal of Synthetic Organic Chemistry, Japan, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Tsutomu Ishikawa, Toshio Isobe
openaire   +2 more sources

Dendritic surface functionalization of nanomaterials: controlling properties and functions for biomedical applications

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
A wide variety of nanomaterials have demonstrated promise in medical applications such as drug delivery and imaging. In these applications, the surface chemistry of the materials is critical as it plays an important role in determining the toxicity and ...
Ali Nazemi, Elizabeth R. Gillies
doaj   +1 more source

Synthesis of Orthogonally N-Protected, C-4 Functionalized Cyclic Guanidines from L-Serine [PDF]

open access: yes, 2017
International audienceA straightforward and efficient preparation of 5-membered cyclic guanidines bearing an ester, a hydroxymethyl or a Weinreb amide functional group at C-4 is described from L-serine.
Cariou, Kevin   +5 more
core   +3 more sources

Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes [PDF]

open access: yes, 2016
Synthetic analogues of marine sponge guanidine alkaloids showed in vitro antiparasitic activity against Leishmania (L.) infantum and Trypanosoma cruzi. Guanidines 10 and 11 presented the highest selectivity index when tested against Leishmania.
Andrade, Carolina H   +26 more
core   +1 more source

PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz

open access: yeseLife, 2017
Dephosphorylation of translation initiation factor 2 (eIF2α) terminates signalling in the mammalian integrated stress response (ISR) and has emerged as a promising target for modifying the course of protein misfolding diseases.
Ana Crespillo-Casado   +4 more
doaj   +1 more source

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