Results 41 to 50 of about 15,901 (303)
Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]
, 2006 Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille +3 more
core +4 more sources
Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species
Molecules, 2018 Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents ...
Aamer Saeed +5 more
doaj +1 more source
“ Thioureidopeptide”: Novel Synthon for the Synthesis of N, N′, N″-Trisubstituted Guanidinopeptide Mimics [PDF]
, 2016 The synthesis of N α-protected N,N′,N″-trisubstituted guanidinopeptide mimic molecules suitably decorated in peptide backbone has been delineated in one pot employing HgCl2 as a desulphurizing agent.
Girish Prabhu, . +4 more
core +1 more source
Antibiotics, 2022 Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers ...
Danzel Marie Ramirez +4 more
doaj +1 more source
Cyclic guanidines. VI. Synthesis of hypoglycemic tricyclic guanidines.
Chemical and Pharmaceutical Bulletin, 1979 Synthesis of linear and angular tricyclic guanidine derivatives, imidazo- or pyrimido-[2, 1-b]- or [1, 2-a] quinazoline derivatives, is described. Cyclization of 2-(ω-chloroalkyl)-4-phenyl-3, 4-dihydroquinazolines (9) gave two isomers and their isolation was troublesome.
A, Kosasayama, K, Higashi, F, Ishikawa
openaire +3 more sources
Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction
Advanced Functional Materials, EarlyView.Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch +13 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche +8 more
wiley +1 more source
Design and synthesis of a photoswitchable guanidine catalyst
Beilstein Journal of Organic Chemistry, 2012 A novel design as well as a straight-forward synthesis for a photoswitchable guanidine catalyst is reported. Intense studies of the photochromic properties demonstrated the reversible switchability of its photosensitive azobenzene moiety. Its activity in
Philipp Viehmann, Stefan Hecht
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2013 A wide variety of nanomaterials have demonstrated promise in medical applications such as drug delivery and imaging. In these applications, the surface chemistry of the materials is critical as it plays an important role in determining the toxicity and ...
Ali Nazemi, Elizabeth R. Gillies
doaj +1 more source
Advanced Materials, EarlyView.All‐perovskite tandem solar cells are evaluated under low‐intensity and low‐temperature (LILT) conditions relevant to space environments. Distinct loss regimes emerge, where weaker entropic mixing causes halide segragation below ≈240 K going along with a strong current imbalance, while poor electron transport in C60 dominates.
Sercan Ozen +10 more
wiley +1 more source