Results 31 to 40 of about 158,534 (314)
Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives [PDF]
Significance Guanine-rich nucleic acids fold into a four-stranded structure named G-quadruplex that has implications in essential cellular processes, pharmaceutical applications, and nanodevices. We found a unique type of G-quadruplex that contains a G-vacancy and is stabilized by guanine derivatives such as te physiological concentration of ...
Xin-min Li+7 more
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A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (
Di Li+6 more
doaj +1 more source
Calculating Hyperfine Couplings in Large Ionic Crystals Containing Hundreds of QM Atoms: Subsystem DFT is the Key [PDF]
We present an application of the linear scaling Frozen Density Embedding (FDE) formulation of subsystem DFT to the calculation of isotropic hyperfine coupling constants (hfccs) of atoms belonging to a guanine radical cation embedded in a guanine hydrochloride monohydrate crystal.
arxiv +1 more source
Probing the microscopic structure and flexibility of oxidized DNA by molecular simulations [PDF]
The oxidative damage of DNA is a compelling issue in molecular biophysics as it plays a vital role in the epigenetic control of gene expression and is believed to be associated with mutagenesis, carcinogenesis, and ageing. To understand the microscopic structural changes in physical properties of DNA and the resulting influence on its function due to ...
arxiv +1 more source
Reductionsproducte aus Guanin [PDF]
n ...
Tafel, Julius, Ach, Benno
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G-quartet biomolecular nanowires [PDF]
We present a first-principle investigation of quadruple helix nanowires, consisting of stacked planar hydrogen-bonded guanine tetramers. Our results show that long wires form and are stable in potassium-rich conditions. We present their electronic bandstructure and discuss the interpretation in terms of effective wide-bandgap semiconductors.
arxiv +1 more source
Flipping Back of Extrahelical Guanine after Methyl Repair
Methylation at O6 atom of guanine is a type of DNA damage which can cause a cancer. This damage at O6 atom of guanine in a DNA can be transferred to SG atom of cysteine in O6-alkylguanine-DNA alkyltransferase (AGT).
Rajendra Prasad Koirala+1 more
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The electrochemical behavior of the interaction of amodiaquine with DNA on a carbon paste electrode was studied using voltametric techniques. In an acid medium, an electroactive adduct is formed when amodiaquine interacts with DNA.
Maria Lara P. M. Arguelho+5 more
doaj +1 more source
Vertically ordered mesoporous silica film (VMSF) with uniform mesoporous channels perpendicular to electrode substrate has a wide range of applications in direct electroanalysis of complex samples.
Luoxing Yang+4 more
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Crystal structure of the nucleoside 2′-deoxyguanosine dimethyl sulfoxide disolvate
The title compound, C10H13N5O4·2C2H6OS, which is of interest with respect to its biological activity, at 183 K has orthorhombic (P212121) crystal symmetry. The structure displays a network of intermolecular N—H...N, N—H...O and O—H...O hydrogen bonds. 2′-
Bernhard Spingler
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