Results 251 to 260 of about 99,476 (367)

Mitochondrial Mutation Leads to Cardiomyocyte Hypertrophy by Disruption of Mitochondria‐Associated ER Membrane

Cell Proliferation, EarlyView.
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu, Min Song, Manna Zhang, Shuangshuang Chen, Baoqiang Ni, Xuechun Li, Wei Lei, Zhenya Shen, Yong Fan, Jianyi Zhang, Shijun Hu   +10 more
wiley   +1 more source

Regulation of opioid antagonist and mu, kappa or delta agonist binding by guanine nucleotide and sodium.

, 1984
Yoshihisa Ishizuka, Tetsuo Oka
openalex   +1 more source

Identification of a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale) responsible for Lesch-Nyhan syndrome. [PDF]

, 1989
Shin Fujimori, Beverly L. Davidson, William N. Kelley, T D Palella   +3 more
openalex   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Human hypoxanthine-guanine phosphoribosyltransferase: a single nucleotide substitution in cDNA clones isolated from a patient with Lesch-Nyhan syndrome (HPRTMidland) [PDF]

, 1988
Beverly L. Davidson, Thomas D. Palella, William N. Kelley   +2 more
openalex   +1 more source

Field-Effect Transistor Based on Nanocrystalline Graphite for DNA Immobilization. [PDF]

Biomolecules
Adiaconita B, Chiriac E, Burinaru T, Marculescu C, Pachiu C, Brincoveanu O, Simionescu O, Avram M.   +7 more
europepmc   +1 more source

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

Cell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li, Yunpeng Zou, Jiayao Niu, Ying Zhang, Aohua Yang, Wenyu Lin, Jie Guo, Shuya Wang, Ronghan Liu   +8 more
wiley   +1 more source

Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.

, 1987
Helen Irving, John H. Exton
openalex   +1 more source

The stimulatory guanine-nucleotide regulatory unit of adenylate cyclase from bovine cerebral cortex ADP-ribosylation and purification [PDF]

, 1987
Eva J. Neer, Luise Wolf, D. Michael Gill
openalex   +1 more source

Ionization of DNA Nucleotides in Explicit Solution. [PDF]

Molecules
Bai J, Zhang Y, Yin S, Che L, Yang S.
europepmc   +1 more source