Results 61 to 70 of about 30,288 (231)

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

(p)ppGpp Metabolism and Antimicrobial Resistance in Bacterial Pathogens

Frontiers in Microbiology, 2020
Single cell microorganisms including pathogens relentlessly face myriads of physicochemical stresses in their living environment. In order to survive and multiply under such unfavorable conditions, microbes have evolved with complex genetic networks ...
Bhabatosh Das, Rupak K. Bhadra
doaj   +1 more source

Advances in the study of core fucosylation in mammals

浙江大学学报. 农业与生命科学版, 2021
Glycosylation is a major posttranslational modification, which involves in the regulation of important physiological functions. Among them, core fucosylation is an α1, 6-linked fucose to N-glycans, which catalyzes by only one glycosyltransferase.
TIAN Yinping, YI Wen
doaj   +1 more source

The synthesis of guanosine 5'-diphosphate D-glucose by enzyme extracts of mung beans (Phaseolus aureus) and other higher plants

, 1985
In response to a statement in the recent literature that the enzyme responsible for the synthesis of guanosine 5'-diphosphate D-glucose had been found only in pea seeds, enzyme extracts were prepared from a variety of higher plants.
G.A. Barber, Barber, G.A.
core   +1 more source

Transcriptomics combined with metabolomics unveiled the key genes and metabolites of mycelium growth in Morchella importuna

Frontiers in Microbiology, 2023
Morels (Morchella) are one of the most popular edible fungi in the world, especially known for their rich nutrition and delicious taste. Earlier research indicates that the production of fruiting bodies can be affected by the growth of mycelium.
Tingting Fan, Rui Ren, Shaojun Tang, Yiyun Zhou, Meng Cai, Wenwen Zhao, Yuelin He, Jun Xu   +7 more
doaj   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Mtb Pck Amino acid (AA) residues forming hydrogen bonds and close contacts (˂ 3.7Å) with guanosine-5'-diphosphate (GDP) in Mtb Pck-GDP-Mn²⁺ complex.

, 2015
Mtb Pck Amino acid (AA) residues forming hydrogen bonds and close contacts (˂ 3.7Å) with guanosine-5'-diphosphate (GDP) in Mtb Pck-GDP-Mn2+ complex.
Iva Machová (709377), Ondřej Vaněk (709383), Jindřich Fanfrlík (709381), Mahavir Singh (70735), Ján Tarábek (709382), Jan Snášel (709378), Lucie Bednárová (709384), Jiří Dostál (709379), Jiří Brynda (709380), Iva Pichová (24761)   +9 more
core   +1 more source

Conserved Golgi nucleoside diphosphatases drive protein glycosylation and virulence in Fusarium graminearum

Phytopathology Research
The Golgi apparatus orchestrates post-translational modification and vesicular trafficking, with guanosine diphosphatases (GDPases) facilitating nucleotide-sugar transport by hydrolyzing guanosine diphosphate (GDP) to guanosine monophosphate (GMP ...
Soobin Shin, Yejin Choi, Thuy Thi Thanh Phan, Seonwoo Song, Nahyun Lee, Jiyeun Park, Sieun Kim, Hosung Jeon, Jung-Eun Kim, Kyunghun Min, Hun Kim, Gyung Ja Choi, Hyun Ah Kang, Dae-Geun Song, Hokyoung Son   +14 more
doaj   +1 more source

Post-Translational Modification and Subcellular Distribution of Rac1: An Update

Cells, 2018
Rac1 is a small GTPase that belongs to the Rho family. The Rho family of small GTPases is a subfamily of the Ras superfamily. The Rho family of GTPases mediate a plethora of cellular effects, including regulation of cytoarchitecture, cell size, cell ...
Abdalla Abdrabou, Zhixiang Wang
doaj   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source