Results 51 to 60 of about 852,730 (306)

Regulation of Enteroendocrine Cell Networks by the Major Human Gut Symbiont Bacteroides thetaiotaomicron

Frontiers in Microbiology, 2020
Gut microbes have critical roles in maintaining host physiology, but their effects on epithelial chemosensory enteroendocrine cells (EEC) remain unclear.
Amisha Modasia, Aimee Parker, Emily Jones, Regis Stentz, Arlaine Brion, Andrew Goldson, Marianne Defernez, Tom Wileman, Tom Wileman, L. Ashley Blackshaw, Simon R. Carding, Simon R. Carding   +11 more
doaj   +1 more source

Taxonomic Features and Comparison of the Gut Microbiome from Two Edible Fungus-Farming Termites (Macrotermes falciger, M. natalensis) Harvested in the Vhembe District of Limpopo, South Africa [PDF]

, 2019
Background Termites are an important food resource for many human populations around the world, and are a good supply of nutrients. The fungus-farming ‘higher’ termite members of Macrotermitinae are also consumed by modern great apes and are implicated ...
Duncan, Frances D., Hofman, Courney A., Honap, Tanvi P., Lesnik, Julie, Lewis, Cecil M., Netschifhefhe, Shandukani R., Schnorr, Stephanie L.   +6 more
core   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain

Gut Microbes, 2022
Ruminococcus gnavus is a prevalent member of the human gut microbiota, which is over-represented in inflammatory bowel disease and neurological disorders. We previously showed that the ability of R.
Erika Coletto, Dimitrios Latousakis, Matthew G. Pontifex, Emmanuelle H. Crost, Laura Vaux, Estella Perez Santamarina, Andrew Goldson, Arlaine Brion, Mohammad K. Hajihosseini, David Vauzour, George M Savva, Nathalie Juge   +11 more
doaj   +1 more source

Emerging trends in 'smart probiotics' : functional consideration for the development of novel health and industrial applications [PDF]

, 2017
The link between gut microbiota and human health is well-recognized and described. This ultimate impact on the host has contributed to explain the mutual dependence between humans and their gut bacteria.
El Hage, Racha, Hernandez Sanabria, Emma, Van de Wiele, Tom   +2 more
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Use of genetically modified bacteria for drug delivery in humans: Revisiting the safety aspect

Scientific Reports, 2017
The use of live, genetically modified bacteria as delivery vehicles for biologics is of considerable interest scientifically and has attracted significant commercial investment.
Udo Wegmann, Ana Lucia Carvalho, Martin Stocks, Simon R. Carding   +3 more
doaj   +1 more source

The Uptake, Trafficking, and Biodistribution of Bacteroides thetaiotaomicron Generated Outer Membrane Vesicles

Frontiers in Microbiology, 2020
Gram-negative bacteria ubiquitously produce and release nano-size, non-replicative outer membrane vesicles (OMVs). In the gastrointestinal (GI-) tract, OMVs generated by members of the intestinal microbiota are believed to contribute to maintaining the ...
Emily J. Jones, Catherine Booth, Sonia Fonseca, Aimee Parker, Kathryn Cross, Ariadna Miquel-Clopés, Isabelle Hautefort, Ulrike Mayer, Tom Wileman, Tom Wileman, Régis Stentz, Simon R. Carding, Simon R. Carding   +12 more
doaj   +1 more source

Chocolate, gut microbiota, and human health [PDF]

Frontiers in Pharmacology, 2013
With the advances in molecular biology techniques, the association between changes in the gut microbiota and human diseases or disorders is becoming more evident. These health issues include aging (Rehman, 2012), oxidative stress (Qiao et al., 2012), blood pressure and atherosclerosis (Queipo-Ortuno, 2012), diabetes (Wen et al., 2008; Larsen et al ...
openaire   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source