Results 51 to 60 of about 3,495 (182)

Tuning Membrane Binding and Lipid Phase Preference of DNA Nanostructures via Synergistic Multi‐Lipidation

open access: yesChemSystemsChem, Volume 8, Issue 5, September 2026.
DNA origami nanostructures functionalized with lipophilic anchors of distinct hydrophobicity reveal synergistic effects on membrane binding and phase‐specific localization. Weak anchors, although insufficient for binding alone, enhance membrane association and govern selective phase partitioning when combined with strong anchors, establishing multi ...
Subhasini Singh, Henri G. Franquelim
wiley   +1 more source

Rapid Multi-Well Evaluation of Assorted Materials for Hydrogel-Assisted Giant Unilamellar Vesicle Production: Empowering Bottom-Up Synthetic Biology

open access: yesGels
Giant unilamellar vesicles (GUVs) are versatile cell models in biomedical and environmental research. Of the various GUV production methods, hydrogel-assisted GUV production is most easily implemented in a typical biological laboratory. To date, agarose,
Cherng-Wen Darren Tan   +2 more
doaj   +1 more source

Environmental Impact of Synthetic Cell Technology: Review of Life Cycle Assessment Data for Feedstocks and Production Methods

open access: yesChemBioChem, Volume 27, Issue 15, 14 August 2026.
Synthetic cells are positioned as enablers of green technology. But what is known about the environmental impact of synthetic cell production? In this review, we examine drivers of greenhouse gas emissions, toxicity, and other environmental impact categories of synthetic cell components.
Christina Hopf   +2 more
wiley   +1 more source

Repurposing a Lipid Droplet‐Associated Algal Protein as a Biosensor for Phosphatidic Acid

open access: yesAdvanced Sensor Research, Volume 5, Issue 8, August 2026.
The DTH1 lipid binding domain (DTH1LBD) binds to lipid membranes containing phosphatidic acid (PA). Its N‐terminal amphipathic helices are sufficient for this association and, when labeled with solvatochromic fluorophores, can serve as in vitro PA biosensors.
Bilge Ercan   +5 more
wiley   +1 more source

Microfluidic Giant Polymer Vesicles Equipped with Biopores for High‐Throughput Screening of Bacteria

open access: yesAdvanced Science
Understanding the mechanisms of antibiotic resistance is critical for the development of new therapeutics. Traditional methods for testing bacteria are often limited in their efficiency and reusability.
Lukas Heuberger   +6 more
doaj   +1 more source

Microfluidic characterization of biomimetic membrane mechanics with an on-chip micropipette

open access: yesMicro and Nano Engineering, 2020
The mechanic properties of cell membranes control many biological processes. The complexity of natural membranes is often dealt with by building synthetic vesicles (Giant Unilamellar Vesicles, GUVs), which can be thought as micron-sized minimal cells ...
Marianne Elias   +9 more
doaj   +1 more source

GUV preparation and assay v1

open access: yes, 2021
LC3 lipidation on GUVs
openaire   +1 more source

Complex Phase Behavior of GUVs Containing Different Sphingomyelins [PDF]

open access: yesBiophysical Journal, 2019
Understanding the lateral organization of biological membranes plays a key role on the road to fully appreciate the physiological functions of this fundamental barrier between the inside and outside regions of a cell. Ternary lipid bilayers composed of a high and a low melting temperature lipid and cholesterol represent a model system that mimics some ...
Balleza D Mescola A MarínMedina N Ragazzini G Pieruccini M Facci P Alessandrini ABalleza D   +6 more
openaire   +3 more sources

Olikomycin A Disrupts Gram‐Positive Bacterial Membranes Through Calcium‐Dependent Binding to Phosphatidylglycerol

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
Olikomycin A, a calcium‐dependent lipopeptide antibiotic, targets Gram‐positive bacteria by binding to phosphatidylglycerol and rapidly disrupting membrane integrity. Unlike daptomycin, it induces extensive membrane remodeling, vesicle deformation, and fragmentation.
Luisa Munz   +4 more
wiley   +1 more source

Quantification of pulsed electric field for the rupture of giant vesicles with various surface charges, cholesterols and osmotic pressures.

open access: yesPLoS ONE, 2022
Electropermeabilization is a promising phenomenon that occurs when pulsed electric field with high frequency is applied to cells/vesicles. We quantify the required values of pulsed electric fields for the rupture of cell-sized giant unilamellar vesicles (
Md Kabir Ahamed   +2 more
doaj   +1 more source

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