Results 91 to 100 of about 24,574 (211)

Genotypic and phenotypic characterization of Mycobacterium tuberculosis resistance against fluoroquinolones in the northeast of Iran

open access: yesBMC Infectious Diseases, 2020
Background Fluoroquinolones are broad-spectrum antibiotics that are recommended, and increasingly important, for the treatment of multidrug-resistant tuberculosis (MDR-TB). Resistance to fluoroquinolones is caused by mutations in the Quinolone Resistance
Mahdieh Sayadi   +7 more
doaj   +1 more source

Targeting homologous recombination repair to potentiate fluoroquinolone efficacy in Mycobacterium abscessus

open access: yes
mLife, EarlyView.
Shuai Wang   +20 more
wiley   +1 more source

Current Helicobacter pylori Diagnostics: Established Methods, Resistance Testing, and Emerging Approaches

open access: yesJGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Aims Accurate diagnosis of Helicobacter pylori infection is required to detect active infection, confirm eradication, assess gastric pathology when indicated, and obtain antimicrobial resistance information that may guide treatment. This review evaluates the clinical roles, limitations, and implementation maturity of established, molecular ...
Tianhua Tang   +9 more
wiley   +1 more source

Study of Mutations in the DNA gyrase gyrA Gene of Escherichia coli.

open access: yesIranian journal of pharmaceutical research : IJPR, 2010
Quinolones are a large and widely consumed class of synthetic drugs. Expanded-spectrum quinolones, like ciprofloxacin are highly effective against Gram-negative bacteria, especially Escherichia coli. In E. coli the major target for quinolones is DNA gyrase.
Pourahmad Jaktaji, R, Mohiti, E
openaire   +2 more sources

Characterisation of Haemolytic Uropathogenic Escherichia coli Isolated From Dogs and Cats

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The present study characterises 51 canine and feline haemolytic E. coli isolates from urinary tract infections by a polyphasic approach, including susceptibility testing, CH‐clonotyping, and DNA microarrays. The majority of isolates belonged to phylogenetic group B2 and were classified as extraintestinal pathogenic E.
Sarah Büttner   +12 more
wiley   +1 more source

Deteksi Mutasi Regio gen gyrA Mycobacterium tuberculosis Resisten Terhadap Fluoroquinolon [PDF]

open access: yes, 2011
Background: Fluoroquinolones are an important class of antibiotics used in the management of bacterial diseases and drug resitance tuberculosis (TB).This study aimed to determined the mechanism of fluoroquinolon resitance in Mycobacterium tuberculosis
Deby Kusumaningrum, NIM010942004
core  

gyrAMutations in Fluoroquinolone-resistantClostridium difficilePCR-027

open access: yesEmerging Infectious Diseases, 2007
To the Editor: Clostridium difficile is the most common cause of bacterial diarrhea in hospitalized patients (1). Antimicrobial drug therapy is the most important risk factor associated with the acquistion of C. difficile, and several antimicrobial agents including clindamycin, amoxicillin, and cephalosporins have been particularly associated with C ...
Drudy, Denise   +3 more
openaire   +5 more sources

Mutations of gyrA gene and parC gene in Streptococcus pneumoniae

open access: yesJournal of the Japanese Association for Infectious Diseases, 2003
Fifty-six levofloxacin-susceptible strains of Streptococcus pneumoniae were isolated from various clinical material in July, 2002 from June, 2001, examined antimicrobial susceptibility testing of levofloxacin and sparfloxacin, and performed analysis of gyrA gene and parC gene. 56 strains were not sparfloxacin-resistance. There was not found to mutation
MIYAMOTO, Hitoshi, MURASE, Mitsuharu
openaire   +3 more sources

Genetic diversity and characteristics of gyrA gene in Neisseria spp [PDF]

open access: yes, 2019
Abstract Background Neisseria meningitidis bacteria characterized by clonal complex (CC4821) showed a high resistance rate to quinolones. The aim of this study was to assess whether the DNA gyrase A gene from N.meningitidis CC4821 strains collected in China featured any specific characteristics compared to other Neisseria species.
Pan Zhao   +4 more
openaire   +1 more source

Detection of gyrA Mutation Among Clinical Isolates of Campylobacter jejuni Isolated in Egypt by MAMA-PCR

open access: yesJournal of Infection in Developing Countries, 2010
Introduction: Campylobacter spp are the major cause of enteritis in humans and more than 90% of reported infections are caused by Campylobacter jejuni. Fluoroquinolones such as ciprofloxacin are the antibiotics of choice for treatment.
Mayar Maged Said   +8 more
doaj   +1 more source

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