Results 1 to 10 of about 14,513 (135)

Computational Screening of Selected Phytochemicals Against Levofloxacin and Metronidazole-Resistant Indonesian H. pylori Strains [PDF]

open access: yesMicroorganisms
The incidence of levofloxacin and metronidazole resistance in H. pylori Indonesian strains is increasing. Conventional approaches to antibacterial discovery are often a protracted process.
Musa Ghufron   +2 more
doaj   +2 more sources

Discovery and druggability evaluation of pyrrolamide-type GyrB/ParE inhibitor against drug-resistant bacterial infection

open access: yesActa Pharmaceutica Sinica B, 2023
The bacterial ATP-competitive GyrB/ParE subunits of type II topoisomerase are important anti-bacterial targets to treat super drug-resistant bacterial infections.
Fangfang Lai, Kangfan Lei
exaly   +3 more sources

Isolation and Characterization of Brenneria nigrifluens Causing Bacterial Shallow Bark Canker of Walnut Trees in Golestan Province, Iran [PDF]

open access: yesJournal of Genetic Resources, 2020
Shallow bark canker incited by Brenneria nigrifluens is considered one of the most dangerous diseases which can cause a significant reduction in walnut and timber production.
Mohammad Razinataj   +3 more
doaj   +1 more source

Ofloxacin resistance in Mycobacterium tuberculosis: An increasing concern

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2021
Multidrug resistance tuberculosis (MDR-TB) associated with the development of resistance to fluoroquinolones (FQs) especially ofloxacin is a matter of concern, as they had been earlier recommended drugs for usage in the MDR-TB treatment regimens, and ...
Ramesh S Kumar   +3 more
doaj   +1 more source

Molecular Characterization and Antibacterial Activities of Photorhabdus and Xenorhabdus from Mizoram, North-East India

open access: yesJournal of Pure and Applied Microbiology, 2023
Photorhabdus and Xenorhabdus are the bacterial symbionts of insect pathogenic nematodes, Heterorhabditis and Steinernema, respectively. This study aims to characterize the bacterial symbionts from Mizoram, North-east India and to evaluate their ...
Mary Lalramchuani   +4 more
doaj   +1 more source

Preparation and Application of Plasmid DNA Reference Material in the Detection of Cronobacter in Infant Formula [PDF]

open access: yesShipin Kexue, 2023
The housekeeping genes atpD, gyrB, infB, fusA and glnS in Cronobacter sakazakii were selected as target sequences to construct plasmid standards for rapidly detecting C. sakazakii.
MA Yueran, WANG Hui, FAN Huixia, ZHAO Hongyang, LU Xing’an, GAO Xiaofeng, KANG Wenyi
doaj   +1 more source

Selective DNA Gyrase Inhibitors: Multi-Target in Silico Profiling with 3D-Pharmacophores

open access: yesPharmaceuticals, 2021
DNA gyrase is an important target for the development of novel antibiotics. Although ATP-competitive DNA gyrase (GyrB) inhibitors are a well-studied class of antibacterial agents, there is currently no representative used in therapy, largely due to ...
Tihomir Tomašič   +8 more
doaj   +1 more source

Genetic polymorphism and phenotypic resistance of Mycobacterium tuberculosis to ofloxacin and moxifloxacin

open access: yesТуберкулез и болезни лёгких, 2020
The objective: to study the phenotypic sensitivity of Mycobacterium tuberculosis (MTB) to fluoroquinolones, ofloxacin and moxifloxacin and correlate it with MTB genome mutations associated with resistance to fluoroquinolones to determine the possibility ...
D. V. Vаkhrushevа   +5 more
doaj   +1 more source

Horizontal Gene Transfer of Fluoroquinolone Resistance-Conferring Genes From Commensal Neisseria to Neisseria gonorrhoeae: A Global Phylogenetic Analysis of 20,047 Isolates

open access: yesFrontiers in Microbiology, 2022
Antimicrobial resistance in Neisseria gonorrhoeae is an important global health concern. The genetically related commensal Neisseria act as a reservoir of resistance genes, and horizontal gene transfer (HGT) has been shown to play an important role in ...
Sheeba Santhini Manoharan-Basil   +4 more
doaj   +1 more source

Phylogenomic Analysis Substantiates the gyrB Gene as a Powerful Molecular Marker to Efficiently Differentiate the Most Closely Related Genera Myxococcus, Corallococcus, and Pyxidicoccus

open access: yesFrontiers in Microbiology, 2021
Rapid and accurate strain identification of the most closely related genera Myxococcus, Corallococcus, and Pyxidicoccus can enhance the efficiency of the mining of novel secondary metabolites through dereplication.
Yang Liu   +8 more
doaj   +1 more source

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