Results 241 to 250 of about 5,738,873 (283)

Morphological and Morphometric Characterisation of Selected Camarodont Sea Urchin (Echinoidea: Camarodonta) Pedicellariae (Paracentrotus lividus, Psammechinus miliaris and Echinus esculentus)

Acta Zoologica, EarlyView.
ABSTRACT Pedicellariae are small appendages on the surface of the echinoid test, involved in defence, cleaning, and locomotion. Pedicellariae in three species of camarodont sea urchins common in UK waters (Paracentrotus lividus [Lamarck, 1816], Psammechinus miliaris [P.L.S Müller, 1771] and Echinus esculentus [Linnaeus, 1758]) are the focus of this ...
H. C. Reinardy, R. Marton, C. Allen, E. Mitchell, L. Brunner, A. D. Hughes, R. A. Jenner   +6 more
wiley   +1 more source

The Moral (Un)Desirability of New Biomedical Technologies as Potential Techno‐Fixes

Bioethics, EarlyView.
ABSTRACT The techno‐fix argument, used to argue against technological interventions that address the consequences of social problems instead of their underlying causes, is increasingly invoked in biomedical discussions. However, especially in biomedicine, the techno‐fix argument remains conceptually underdeveloped.
Lieke van Kempen, Martine C. de Vries, Nienke de Graeff   +2 more
wiley   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Quinoxaline in Auditory Hair Cell Regeneration

American Journal of Pharmaceutical Education
E. Jeffrey North, Lily Calisto, Brock Barthol, Kenneth Nguyen, Sonia Rocha-Sanchez   +4 more
openaire   +1 more source

Live Imaging of Stem Cell and Progeny Behaviour in Physiological Hair-Follicle Regeneration [PDF]

Nature, 2012
Tissue development and regeneration depend on cell-cell interactions and signals that target stem cells and their immediate progeny. However, the cellular behaviours that lead to a properly regenerated tissue are not well understood.
Ann M Haberman, Panteleimon Rompolas, David G Gonzalez   +2 more
exaly   +2 more sources

The Challenge of Hair Cell Regeneration [PDF]

Experimental Biology and Medicine, 2010
Sensory hair cells of the inner ear are responsible for translating auditory or vestibular stimuli into electrical energy that can be perceived by the nervous system. Although hair cells are exquisitely mechanically sensitive, they can be easily damaged by excessive stimulation by ototoxic drugs and by the effects of aging.
Andrew K. Groves
exaly   +3 more sources

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Hair Cell Regeneration

Advances in Experimental Medicine and Biology, 2019
Cochlear hair cells are mechanoreceptors of the auditory system and cannot spontaneously regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In contrast, hair cells in nonmammalian vertebrates such as birds and in the zebrafish lateral line have the ability to regenerate after hair cell loss.
Huawei Li, Renjie Chai, Shasha Zhang
exaly   +3 more sources

Losing the license to regenerate hair cells

Developmental Cell, 2021
Regenerative repair decreases in many organs as tissue matures. In this issue of Developmental Cell, Tao et al. (2021) identify epigenetic mechanisms that coincide with temporal loss of regenerative potential in the mammalian inner ear.
Marielle O, Beaulieu, David W, Raible
openaire   +2 more sources

Hair Cell Regeneration in the Inner Ear

Otolaryngology–Head and Neck Surgery, 1994
Hearing and balance disorders caused by the loss of inner ear hair cells Is a common problem encountered in otolaryngology‐head and neck surgery. The postembryonic production of hair cells in cold‐blooded vertebrates has been known for several decades, and recent studies in the avian inner ear after ototoxic drug and noise damage have demonstrated a ...
T T, Tsue, E C, Oesterle, E W, Rubel
openaire   +2 more sources

Current Concepts in Hair Cell Regeneration

Otolaryngologic Clinics of North America, 1993
Hair cell regeneration following various mechanical or chemical insults to the inner ear has become the subject of intense scientific research. This article details current concepts relating to this topic, including descriptions of the hair cell precursor population, the ultrastructural properties of the newly regenerated hair cells, and regeneration ...
L G, Duckert, E W, Rubel
openaire   +2 more sources