Results 251 to 260 of about 5,738,873 (283)

Hair cell regeneration in senescent quail

Hearing Research, 1990
Hair cell regeneration was studied following exposure to an intense pure tone stimulus in young adult and senescent Coturnix quail. Three, 3-month old and four, 3-year old quail were continuously exposed to a 1500 Hz pure tone at 115 dB SPL for 12 h. Four quail were not noise exposed and were used as age-matched controls. Control and experimental birds
B M, Ryals, E W, Westbrook
openaire   +2 more sources

Regeneration of Hair Cells in the Mammalian Vestibular System

Frontiers of Medicine, 2016
Hair cells regenerate throughout the lifetime of non-mammalian vertebrates, allowing these animals to recover from hearing and balance deficits. Such regeneration does not occur efficiently in humans and other mammals. Thus, balance deficits become permanent and is a common sensory disorder all over the world.
Huawei Li, Wenyan Li, Yan Chen
exaly   +3 more sources

Hair Follicle Stem Cells for Tissue Regeneration

Tissue Engineering Part B: Reviews, 2022
With the positive outcomes of various cell therapies currently under preclinical and clinical studies, there is a significant interest in novel stem cell sources with unique therapeutic properties. Studies over the past two decades or so demonstrated the feasibility to isolate multipotent/pluripotent stem cells from hair follicles.
Alyssa, Peterson, Lakshmi S, Nair
openaire   +2 more sources

Biotechnology in the Treatment of Sensorineural Hearing Loss: Foundations and Future of Hair Cell Regeneration

Journal of Speech, Language, and Hearing Research, 2011
PurposeTo provide an overview of the methodologies involved in the field of hair cell regeneration. First, the author provides a tutorial on the biotechnological foundations of this field to assist the reader in the comprehension and interpretation of ...
Mark A Parker
exaly   +2 more sources

Hair Cell Regeneration in the Inner Ear: A Review

Clinical Otolaryngology, 2003
Hair cell regeneration has been shown to occur in the inner ear of mammals. Specifically, it has been demonstrated in the vestibular system and not the organ of Corti. Recent evidence suggests that the degree of the regenerative response may be augmented pharmacologically.
P, Walshe, M, Walsh, R, McConn Walsh
exaly   +3 more sources

Stimulating hair cell regeneration: On a wing and a prayer

Nature Medicine, 1996
Identifying the mechanisms that regulate hair cell regeneration may contribute to developing treatments for hearing loss in humans (pages 1136–1139).
E W, Rubel, J S, Stone
openaire   +2 more sources

Hair cell regeneration in the avian vestibular epithelium

Experimental Neurology, 1992
Research conducted in the past 4 years has shown that the avian vestibular system retains the capacity to generate hair cells postnatally. In the present paper we review information on postnatal proliferation and differentiation of hair cells in the avian vestibular system.
P, Weisleder, E W, Rubel
openaire   +2 more sources

LSD1 is Required for Hair Cell Regeneration in Zebrafish

Molecular Neurobiology, 2015
Lysine-specific demethylase 1 (LSD1/KDM1A) plays an important role in complex cellular processes such as differentiation, proliferation, apoptosis, and cell cycle progression. It has recently been demonstrated that during development, downregulation of LSD1 inhibits cell proliferation, modulates the expression of cell cycle regulators, and reduces hair
Yingzi, He, Dongmei, Tang, Chengfu, Cai, Renjie, Chai, Huawei, Li   +4 more
openaire   +2 more sources

The Role of Mesenchymal Stem Cells in Hair Regeneration and Hair Cycle

Stem Cells and Development
The health of hair is directly related to people's health and appearance. Hair has key physiological functions, including skin protection and temperature regulation. Hair follicle (HF) is a vital mini-organ that directly impacts hair growth. Besides, various signaling pathways and molecules regulate the growth cycle transition of HFs.
Cong Ma, Ming Cheng, Yan Wu, Xuegang Xu
openaire   +2 more sources

The Cell Cycle and the Development and Regeneration of Hair Cells

2003
Abstract The replication of cells occurs by a process known as the cell cycle, which is under multiple forms of regulation. Cell proliferation is an integral part of the development of the inner ear. Generation of the otic sensory epithelia involves coordinated periods of cell division. However, commitment of cells in the developing sensory epithelia
openaire   +2 more sources