Results 41 to 50 of about 50,821 (291)
Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear.
PLoS ONE, 2012 During embryonic development, hair cells and support cells in the sensory epithelia of the inner ear derive from progenitors that express Sox2, a member of the SoxB1 family of transcription factors.
Stephen D Freeman, Nicolas Daudet
doaj +1 more source
eLife, 2021 Acoustic overexposure and aging can damage auditory synapses in the inner ear by a process known as synaptopathy. These insults may also damage hair bundles and the sensory transduction apparatus in auditory hair cells.
John Lee +3 more
doaj +1 more source
C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient.
PLoS ONE, 2021 Hearing depends on the transduction of sounds into neural signals by the inner hair cells of the cochlea. Cochleae also have outer hair cells with unique electromotile properties that increase auditory sensitivity, but they are particularly susceptible ...
Joyshree Biswas +8 more
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Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss
Cells, 2022 Peroxisome Biogenesis Disorders (PBD) and Zellweger syndrome spectrum disorders (ZSD) are rare genetic multisystem disorders that include hearing impairment and are associated with defects in peroxisome assembly, function, or both.
Stephanie A. Mauriac +4 more
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Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]
, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
core +1 more source
A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells
Cell Discovery, 2019 Dear Editor, F-actin is expressed in almost all cells, and plays a variety of important roles. In the cuticular plate of hair cells, they are thought to be critical in mammalian hearing by holding the stereocilia rootlets in place and providing the ...
J. Qi +8 more
semanticscholar +1 more source
Zinc-finger protein A20 protects hair cells from damage made by high-power microwave
Journal of Bio-X Research, 2019 . Inner ear hair cells are important for maintaining hearing. Irreversible damage to hair cells is an important cause of sensorineural deafness. Electromagnetic radiation, especially high-power microwave, is an important threat to human health in modern ...
Feng Tang +5 more
doaj +1 more source
Protective effect of astaxanthin nanoemulsion on mammalian inner ear hair cells [PDF]
PeerJ, 2023 Background Aminoglycoside antibiotics are used for treating certain acute infections. However, these drugs cause ototoxicity by inducing inner ear hair cell death.
Yuki Kobayashi +6 more
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The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]
, 2009 Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen +2 more
core +1 more source
Journal of Neuroscience, 2019 Transmitter release at auditory inner hair cell (IHC) ribbon synapses involves exocytosis of glutamatergic vesicles during voltage activation of L-type Cav1.3 calcium channels. At these synapses, the fast and indefatigable release of synaptic vesicles by
Margot Tertrais +7 more
semanticscholar +1 more source