Results 71 to 80 of about 37,698 (205)
Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance
Scientific Reports, 2017 The mammalian sense of hearing relies on two types of sensory cells: inner hair cells transmit the auditory stimulus to the brain, while outer hair cells mechanically modulate the stimulus through active feedback.
Nikola Ciganović +2 more
doaj +1 more source
, 2020 Anatomical middle and inner ear parameters are often used to predict hearing sensitivities of mammalian species. Given that ear morphology is substantially affected both by phylogeny and body size, it is interesting to consider whether the relatively ...
Burda, H., Malkemper, E., Mason, M.
core +1 more source
Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid [PDF]
, 2016 With their essential role in inner-ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by crosslinkers of the plastin, fascin, and espin families.
Avenarius +59 more
core +2 more sources
Hearing Research, 2020 In different animal models, auditory nerve fibers display variation in spontaneous activity and response threshold. Functional and structural differences among inner hair cell ribbon synapses are believed to contribute to this variation. The relative volumes of synaptic proteins at individual synapses might be one such difference. This idea is based on
Reijntjes, Daniël O. J. +2 more
openaire +3 more sources
NAVIS: Neuromorphic Auditory VISualizer Tool [PDF]
, 2017 This software presents diverse utilities to perform the first post-processing layer taking the neuromorphic auditory sensors (NAS) information. The used NAS implements in FPGA a cascade filters architecture, imitating the behavior of the basilar membrane
Domínguez Morales, Juan Pedro +3 more
core
Transmitter release from cochlear hair cells is phase locked to cyclic stimuli of different intensities and frequencies [PDF]
, 2012 The auditory system processes time and intensity through separate brainstem pathways to derive spatial location as well as other salient features of sound.
Goutman, Juan Diego
core +1 more source
Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing
Cell Reports, 2019 Summary: Single-cell RNA sequencing is a powerful tool by which to characterize the transcriptional profile of low-abundance cell types, but its application to the inner ear has been hampered by the bony labyrinth, tissue sparsity, and difficulty ...
Paul T. Ranum +7 more
doaj +1 more source
Expression and Localization of CaBP Ca2+ Binding Proteins in the Mouse Cochlea. [PDF]
PLoS ONE, 2016 CaBPs are a family of EF-hand Ca2+ binding proteins that are structurally similar to calmodulin. CaBPs can interact with, and yet differentially modulate, effectors that are regulated by calmodulin, such as Cav1 voltage-gated Ca2+ channels ...
Tian Yang +5 more
doaj +1 more source
Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]
, 2019 Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J. +6 more
core +2 more sources
Tsukushi is essential for the development of the inner ear
Molecular Brain, 2020 Tsukushi (TSK)—a small, secreted, leucine-rich-repeat proteoglycan—interacts with and regulates essential cellular signaling cascades. However, its functions in the mouse inner ear are unknown.
Toru Miwa +8 more
doaj +1 more source