Results 81 to 90 of about 37,698 (205)

Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]

, 2011
Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin, Plath, Martin, Schulz-Mirbach, Tanja   +2 more
core   +1 more source

Correct Timing of Proliferation and Differentiation is Necessary for Normal Inner Ear Development and Auditory Hair Cell Viability [PDF]

Developmental Dynamics, 2013
Background: Hearing restoration through hair cell regeneration will require revealing the dynamic interactions between proliferation and differentiation during development to avoid the limited viability of regenerated hair cells. Pax2‐Cre N‐Myc conditional knockout (CKO) mice highlighted the need of N‐Myc for proper neurosensory development and ...
Benjamin J, Kopecky, Israt, Jahan, Bernd, Fritzsch   +2 more
openaire   +2 more sources

The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse [PDF]

, 2018
The ribbon is the structural hallmark of cochlear inner hair cell (IHC) afferent synapses, yet its role in information transfer to spiral ganglion neurons (SGNs) remains unclear.
Becker, Lars, Kachar, Bechara, Maxeiner, Stephan, Niwa, Mamiko, Ricci, Anthony J, Rutherford, Mark A, Schnee, Michael E, Sun, Willy, Talaei, Sara   +8 more
core   +2 more sources

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce, D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, DE VIRGILIO, ARMANDO, DI STADIO, Arianna, GRECO, Antonio, LONGO, Lucia, RALLI, MASSIMO   +7 more
core   +1 more source

Concurrent Maturation of Inner Hair Cell Synaptic Ca2+ Influx and Auditory Nerve Spontaneous Activity around Hearing Onset in Mice [PDF]

Journal of Neuroscience, 2013
Hearing over a wide range of sound intensities is thought to require complementary coding by functionally diverse spiral ganglion neurons (SGNs), each changing activity only over a subrange. The foundations of SGN diversity are not well understood but likely include differences among their inputs: the presynaptic active zones (AZs) of inner hair cells (
Wong, Aaron B, Jing, Zhizi, Rutherford, Mark A, Frank, Thomas, Strenzke, Nicola, Moser, Tobias   +5 more
openaire   +5 more sources

Viral-mediated Ntf3 overexpression disrupts innervation and hearing in nondeafened guinea pig cochleae

Molecular Therapy: Methods & Clinical Development, 2016
Synaptopathy in the cochlea occurs when the connection between inner hair cells and the auditory nerve is disrupted, leading to impaired hearing and nerve degeneration. Experiments using transgenic mice have shown that overexpression of NT3 by supporting
Min Young Lee, Takaomi Kurioka, Megan M Nelson, Diane M Prieskorn, Donald L Swiderski, Yohei Takada, Lisa A Beyer, Yehoash Raphael   +7 more
doaj   +1 more source

Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice

Neural Plasticity, 2018
The auditory function develops and matures after birth in many mammalian species. After hearing onset, environmental sounds exert profound and long-term effects on auditory functions.
Aoshuang Chang, Peng Chen, Shasha Guo, Nana Xu, Wenlu Pan, Hongzheng Zhang, Cuixian Li, Jie Tang   +7 more
doaj   +1 more source

Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results

Brazilian Journal of Medical and Biological Research, 2016
In mammals, damage to sensory receptor cells (hair cells) of the inner ear results in permanent sensorineural hearing loss. Here, we investigated whether postnatal mouse inner ear progenitor/stem cells (mIESCs) are viable after transplantation into the ...
L.C.M. Barboza Jr., K. Lezirovitz, D.B. Zanatta, B.E. Strauss, R.C. Mingroni-Netto, J. Oiticica, L.A. Haddad, R.F. Bento   +7 more
doaj   +1 more source

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]

, 2015
Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E, Biscaro, A, Cama, Elona, Caporali, L, Carelli, V., La Morgia, C, Liguori, R, Magnavita, V, Monteleone, A, Rossi, R, Santarelli, Rosamaria, Scimemi, Pietro, Valentino, Ml   +12 more
core   +3 more sources

Age-related changes in olivocochlear efferent innervation in gerbils

Frontiers in Synaptic Neuroscience
IntroductionAge-related hearing difficulties have a complex etiology that includes degenerative processes in the sensory cochlea. The cochlea comprises the start of the afferent, ascending auditory pathway, but also receives efferent feedback innervation
Friederike Steenken, Friederike Steenken, Asli Pektaş, Christine Köppl, Christine Köppl, Christine Köppl   +5 more
doaj   +1 more source