Results 181 to 190 of about 119,470 (327)
ABSTRACT Bats have evolved highly adapted auditory mechanisms associated with ecological specialisation. However, there is scattered knowledge about the neurophysiological and cellular basis underlying high‐frequency hearing in echolocating bats. Herein, the total cochlear cell atlas of Rhinolophus ferrumequinum (constant frequency (CF) bat) and Myotis
Xue Wang+14 more
wiley +1 more source
Xiaowei Lu, C. Sipe
semanticscholar +1 more source
The mechanisms of frequency tuning in gecko auditory hair cells
We developed an isolated auditory papilla of the crested gecko to record from the hair cells and explore the origins of frequency tuning. Low-frequency cells displayed electrical tuning, dependent on Ca2+-activated K+ channels; high-frequency cells, overlain with sallets, showed a variation in hair bundle stiffness which when combined with sallet mass ...
Robert, Fettiplace, Maryline, Beurg
openaire +2 more sources
DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy
In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding+8 more
wiley +1 more source
Attraction in every sense: How looks, voice, movement and scent draw us to future lovers and friends
Abstract What makes someone attractive has been examined for faces, in terms of common preferences, and for opposite‐sex interactions. We expanded on this by considering also other non‐verbal modalities, personal preferences and same‐sex interactions.
Annett Schirmer+6 more
wiley +1 more source
Re‐make, re‐model: evolution and development of vertebrate cranial lateral lines
ABSTRACT Lateral lines are placodally derived mechanosensory systems on the heads and trunks of many aquatic vertebrates. There is evidence of lateral lines in the earliest known vertebrate fossils, and they exist in organisms with widely different craniofacial morphologies – including the presence or absence of jaws, external or internal nostrils, and
Vishruth Venkataraman+3 more
wiley +1 more source
Our mouse model with a c.259G>A transition in PRPS1 showed a significant decrease in the number of hair cells and SGN counts at 48 weeks of age and a reduction in Prps1 enzymatic activity in the KI mouse. This model will serve as a valuable tool for developing therapeutic strategies.
Denise Yan+6 more
wiley +1 more source
Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai+9 more
wiley +1 more source
A. Brugeaud, M. Tong, Li-Da Luo, A. Edge
semanticscholar +1 more source
Have significant biodiversity values been protected from industrial logging across Australia?
Abstract Much of the planet's forest biodiversity is at risk from a range of threats. Threats include gaps in the protected area network and instances where these gaps are subject to intensive industrial logging. These gaps are referred to as optimal areas for protection and we sought to determine if certification schemes maintained the environmental ...
Chris Taylor+4 more
wiley +1 more source